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Sulfacetamide (sodium salt)
Sulfacetamide (sodium salt)

Item number: Cay20377-50

Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC50 = 9.6 µM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid (Cay-18659), which is required for the synthesis of...
Keywords: N-acetyl Sulfanilamide, N-[(4-aminophenyl)sulfonyl]-acetamide, monosodium salt
Application: Antibacterial, Folic acid biosynthesis inhibitor
CAS 127-56-0
MW: 236.2 D
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Sulfanilamide
Sulfanilamide

Item number: Cay23723-5

Sulfanilamide is a sulfonamide antibiotic. It is bacteriostatic against Streptococcus when used at a concentration of 20 µg/ml and inhibits the growth of 106 clinical isolates of Gonococcus at 0.01% v/v. Sulfanilamide reduces plasma levels of Streptococcus in infected rabbits. It is an inhibitor of carbonic...
Keywords: p-Aminobenzenesulfonamide, 4-Aminobenzenesulfonamide, NSC 7618, Ro 1-3354, 4-amino-benzenesulfonamide
Application: Antibacterial, folic acid biosynthesis inhibitor
CAS 63-74-1
MW: 172.2 D
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Sulfamerazine (sodium salt)
Sulfamerazine (sodium salt)

Item number: Cay23380-10

Sulfamerazine is a sulfonamide antibiotic. It inhibits dihydropteroate synthase (DHPS, IC50 = 11.26 ng/ml for the S. pneumoniae enzyme) and bacterial carbonic anhydrase by ~20% when used at a concentration of 500 µM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated...
Keywords: 4-amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide, monosodium salt
Application: Antibacterial, folic acid biosynthesis inhibitor, dihydropteroate synthase inhibitor
CAS 127-58-2
MW: 286.3 D
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Sulfadiazine
Sulfadiazine

Item number: Cay23719-25

Sulfadiazine is a sulfonamide antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (DHPS), which converts a pteridine and 4-aminobenzoic acid (PABA, Cay-18659) to dihydropteroate, an intermediate in folate biosynthesis. Sulfadiazine inhibits...
Keywords: NSC 35600, 4-amino-N-2-pyrimidinyl-benzenesulfonamide
Application: Sulfonamide antibiotic
CAS 68-35-9
MW: 250.3 D
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Mafenide
Mafenide

Item number: Cay23995-100

Mafenide is a sulfonamide antibiotic that inhibits growth of bacteria. It inhibits growth of clinical isolates of S. pyogenes, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. aureus (MRSA), Enterococcus, Enterobacteriaceae, and Gram-negative bacilli from burn patients in an agar well diffusion...
Keywords: NSC 34632, 4-(aminomethyl)-benzenesulfonamide
Application: Sulfonamide antibiotic, Folic acid biosynthesis inhibitor
CAS 138-39-6
MW: 186.2 D
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N-acetyl Sulfamethoxazole
N-acetyl Sulfamethoxazole

Item number: Cay17247-10

N-acetyl Sulfamethoxazole is a metabolite of sulfamethoxazole, an antibiotic with antiviral activity, that can be detected in urine.Formal Name: N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-acetamide. CAS Number: 21312-10-7. Synonyms: STX 606. Molecular Formula: C12H13N3O4S. Formula Weight: 295.3. Purity:...
Keywords: STX 606, N-[4-[[(5-methyl-3-isoxazolyl)amino]sulfonyl]phenyl]-acetamide
Application: Sulfamethoxazole metabolite, Antiviral
CAS 21312-10-7
MW: 295.3 D
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Sulfamethazine
Sulfamethazine

Item number: Cay20976-25

Sulfamethazine is a sulfonamide antibiotic. It inhibits dihydropteroate synthase (DHPS, IC50 = 5.7 µM for the T. gondii enzyme). Sulfamethazine is active against A. pleuropneumoniae (MIC = 32 µg/ml) and enhances the antibacterial activity of trimethoprim (Cay-16473) against E. coli. It has been detected in...
Keywords: NSC 67457, NSC 683529, Sulfadimethyldiazine, Sulfadimidine, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-benzenesulfonamide
Application: Antibacterial sulfonamide, Dihydropteroate synthase inhibitor
CAS 57-68-1
MW: 278.3 D
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Sulfamethoxazole
Sulfamethoxazole

Item number: Cay23613-25

Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 µg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 25-50 µg/ml). Sulfamethoxazole, in combination with trimethoprim (Cay-16473) at a ratio of 20:1, inhibits growth of MRSA in vivo in mice (MIC = 0.8...
Keywords: NSC 147832, Ro 4-2130, 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide
Application: Antibacterial, Folic acid biosynthesis inhibitor
CAS 723-46-6
MW: 253.3 D
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Sulfamethizole
Sulfamethizole

Item number: Cay23355-250

Sulfamethizole is a broad spectrum sulfonamide antibiotic (MIC90s = 1.25-5,000 µg/ml against clinical isolates of E. coli and K. pneumoniae). It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract...
Keywords: N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)-benzenesulfonamide
Application: Antibiotic, Dihydropteroate synthase inhibitor
CAS 144-82-1
MW: 270.3 D
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Sulfamethoxypyridazine
Sulfamethoxypyridazine

Item number: Cay21875-5

Sulfamethoxypyridazine is a sulfonamide antibiotic that inhibits the growth of Gram-negative bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 17 nM) and folate biosynthesis in P. carinii by 75% when used at a concentration of 50 nM. Sulfamethoxypyridazine...
Keywords: 4-amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide
Application: Antibacterial sulfonamide antibiotic, Folic acid biosynthesis inhibitor
CAS 80-35-3
MW: 280.3 D
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Sulfamethizole-d4
Sulfamethizole-d4

Item number: Cay26789-1

Sulfamethizole-d4 is intended for use as an internal standard for the quantification of sulfamethizole (Cay-23355) by GC- or LC-MS. Sulfamethizole is a broad-spectrum sulfonamide antibiotic (MIC90s = 1.25-5,000 µg/ml against clinical isolates of E. coli and K. pneumoniae). It inhibits dihydropteroate synthase, an...
Keywords: N1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide-d4, 4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-d4-sulfonamide
Application: GC-MS, LC-MS, Quantification, Internal standard, Antibiotic, Dihydropteroate synthase inhibitor
CAS 2470130-12-0
MW: 274.3 D
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Sulfisoxazole
Sulfisoxazole

Item number: Cay25980-1

Sulfisoxazole is a sulfonamide antibiotic and nonpeptide endothelin (ET) receptor antagonist (IC50s = 0.6 and 22 µM for the ETA and ETB receptors, respectively). It inhibits the growth of Gram-positive and Gram-negative bacteria in vitro, including S. pneumoniae, B. subtilis, S. epidermidis, E. coli, and K....
Keywords: NSC 13120, NSC 33807, NSC 38588, NSC 683536, Sulfafurazole, 4-amino-N-(3,4-dimethyl-5-isoxazolyl)-benzenesulfonamide
Application: Sulfonamide antibacterial, Folic acid biosynthesis inhibitor
CAS 127-69-5
MW: 267.3 D
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Sulfameter
Sulfameter

Item number: Cay27630-5

Sulfameter is a long-acting sulfonamide antibiotic. In vitro, it is active against the bacteria D. pneumoniae, K. pneumoniae, E. coli, N. meningitidis, P. vulgaris, S. aureus, S. haemolyticus, and S. typhimurium in a disc assay. Sulfameter is efficacious against lethal K. pneumoniae, E. coli, P. vulgaris, D....
Keywords: Bayrena, NSC 683528, Sulfamethoxydiazine, 4-amino-N-(5-methoxy-2-pyrimidinyl)-benzenesulfonamide
Application: Antibacterial, Sulfonamide antibiotic
CAS 651-06-9
MW: 280.3 D
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Sulfamoxole
Sulfamoxole

Item number: Cay19537-25

Sulfamoxole is a sulfonamide antibiotic. It is inactive or weakly active against bacteria when used alone but acts synergistically with trimethoprim (Cay-16473) against a variety of bacteria in vitro, including strains of S. pyogenes, E. coli, and P. vulgaris when used at concentrations of 1.95-7.8, 0.12-1.95, and...
Keywords: NSC 683535, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-benzenesulfonamide
Application: Sulfonamide antibiotic, Antibacterial, Folic acid biosynthesis inhibitor
CAS 729-99-7
MW: 267.3 D
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Sulfapyridine
Sulfapyridine

Item number: Cay28619-5

Sulfapyridine is a sulfonamide antibiotic with antibacterial and anti-inflammatory activities. It is also a metabolite of sulfasalazine (Cay-15025) formed through bacterial conversion in the colon. It is active against strains of Y. enterocolitica and Salmonella (MICs = 3.1-25 and 25-100 µg/ml, respectively), as...
Keywords: NSC 41791, NSC 4753, Sulphapyridine, 4-amino-N-2-pyridinyl-benzenesulfonamide
Application: Sulfonamide antibiotic, antibacterial, folic acid biosynthesis inhibitor
CAS 144-83-2
MW: 249.3 D
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Sulfadimethoxine
Sulfadimethoxine

Item number: Cay28827-5

Sulfadimethoxine is a sulfonamide antibiotic that is active against Gram-negative and Gram-positive bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 25 nM), an enzyme required for folate biosynthesis, in a cell-free assay. Sulfadimethoxine is active against...
Keywords: Sulphadimethoxine, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamide
Application: Sulfonamide antibiotic, antibacterial, folic acid biosynthesis inhibitor
CAS 122-11-2
MW: 310.3 D
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Cotrimoxazole
Cotrimoxazole

Item number: Cay30781-250

Cotrimoxazole is a mixture of the antibiotics sulfamethoxazole (Cay-23613) and trimethoprim (Cay-16473). It is bactericidal against 12 patient-derived community-acquired methicillin-resistant S. aureus (MRSA) strains when used at a concentration of 0.05 mg/L. Cotrimoxazole (240 mg/kg) prevents lung and spleen...
Keywords: TMP-SMX, Trimethoprim-Sulfamethoxazole, 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine mixture with...
Application: Antibiotics mixture
CAS 8064-90-2
MW: 543.6 D
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Sulfaclozine (sodium salt)
Sulfaclozine (sodium salt)

Item number: Cay31223-100

Sulfaclozine is a sulfonamide antibiotic with antiprotozoal activity. Dietary administration of sulfaclozine reduces cecal lesion score and oocyst production in a chick model of E. tenella infection in a dose-dependent manner. It increases average survival time in a mouse model of T. gondii infection when...
Keywords: Sulfachloropyrazine, Sulphachloropyrazine, 4-amino-N-(6-chloro-2-pyrazinyl)-benzenesulfonamide, monosodium salt
Application: Sulfonamide antibiotic, antiprotozoal agent, coccidiostat
CAS 23307-72-4
MW: 306.7 D
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Sulfadiazine-d4
Sulfadiazine-d4

Item number: Cay33605-1

Sulfadiazine-d4 is intended for use as an internal standard for the quantification of sulfadiazine (Cay-23719) by GC- or LC-MS. Sulfadiazine is a sulfonamide antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (DHPS), which converts a pteridine and...
Keywords: 4-amino-N-2-pyrimidinyl-benzene-2,3,5,6-d4-sulfonamide
Application: GC-MS, LC-MS internal standard, quantification, sulfonamide antibiotic
CAS 1020719-78-1
MW: 254.3 D
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