41 products were found matching "P52333"!

JAK3 is a non-receptor tyrosine kinase that has roles in cytokine signaling and immune cell function.1,2 It is composed of N-terminal FERM and SH2 domains, a regulatory JH2 pseudokinase domain, and a C-terminal kinase domain.2,3 JAK3 is constitutively expressed in natural killer (NK) cells and thymocytes and...

JAK3 is a non-receptor tyrosine kinase that has roles in cytokine signaling and immune cell function.1,2 It is composed of N-terminal FERM and SH2 domains, an autoinhibitory JH2 pseudokinase domain, and a C-terminal kinase domain.3,2,4 JAK3 is constitutively expressed in natural killer (NK) cells and thymocytes and...

JAK3 is a non-receptor tyrosine kinase that has roles in cytokine signaling and immune cell function.1,2 It is composed of N-terminal FERM and SH2 domains, an autoinhibitory JH2 pseudokinase domain, and a C-terminal kinase domain.2,3 JAK3 is constitutively expressed in natural killer (NK) cells and thymocytes and...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...

Protein function: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in...

Active human Jak3 (GenBank Accession No. NM_000215), (a.a. 781-end) with N-terminal 10x His-tag, MW= 37 kDa, expressed in Baculovirus expression system.

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin...

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin...

Protein function: Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in...