Protein function: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. [The UniProt Consortium]

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Furin is a member of the proprotein convertase (PC) family, which belongs to the subtilisin superfamily of serine proteases. As a cellular protease, Furin processes a variety of proproteins in secretory pathway compartments by cleaving after ArgXaaLys/ArgArglike motifs, which usually reside at the end of the pro...

Source:, Recombinant Mouse from E. coli, Purity: >95%, Endotoxin: 1.0EU per 1ug (determined by the LAL method), Accession No: P23188, Fragment: Arg418~Thr573 (Accession No: P23188), Sequence: MGHHHHHHSGSEF-RKVSHSYGYG LLDAGAMVAL AQNWTTVAPQ RKCIVEILVE PKDIGKRLEV RKAVTACLGE PNHITRLEHV QARLTLSYNR RGDLAIHLIS PMGTRSTLLA...