21 products were found matching "P04187"!

Description: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible...

ELISA Type: Sandwich. Detection Range: 1.563-100µg/mL. Sensitivity: 0.938µg/mL. Sample Types: Serum, Plasma. Protein function: Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They...

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of GzmB in serum, plasma and other biological fluids. Detection Range: 15.63--1000pg/mL. Sensitivity: 9.38pg/mL. Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp....

Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active...

ELISA Type: Sandwich. Sensitivity: 9.375pg/mL. Range: 15.625--1000pg/mL. Protein function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis...

Protein function: Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Asp. Once delivered into the target cell, acts by catalyzing cleavage of gasdermin-E...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GZMB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GZMB. Next,...

Sample Types: serum, plasma, tissue homogenates Detection Range: 12.5 pg/mL-800 pg/mL Sensitivity: 3.12 pg/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Abundant protease in the cytosolic granules of cytotoxic T- cells and...

Matched antibody pair. Protein function: Abundant protease in the cytosolic granules of cytotoxic T- cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse (PubMed:35705808). It cleaves after Asp (PubMed:35705808). Once delivered into...

Granzyme B (GZMB) BioAssay(TM) ELISA Kit (Mouse) is a sandwich enzyme immunoassay for in vitro quantitative measurement of GZMB in mouse serum, plasma, tissue homogenates and other biological fluids. Detection Range: 15.6-1,000pg/ml, Sensitivity: 6.2pg/ml, Storage and Stability: Desiccation recommended. The...

Source:, Recombinant Mouse from E. coli, Purity: >95%, Endotoxin: 1.0EU per 1ug (determined by the LAL method), Accession No: P04187, Fragment: Thr16~Met244 (Accession No: P04187), Sequence: MRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH...