64 products were found matching "K22182"!

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-497aa. Protein Length: Partial of Isoform 5. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MNGPEDLPKS YDYDLIIIGG GSGGLAAAKE AAQYGKKVMV LDFVTPTPLG TRWGLGGTCV NVGCIPKKLM HQAALLGQAL QDSRNYGWKV EETVKHDWDR MIEAVQNHIG SLNWGYRVAL REKKVVYENA...

Organism: Drosophila melanogaster (Fruit fly). Source: E.coli. Expression Region: 111-588aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GSYDYDLIVI GGGSAGLACA KEAVLNGARV ACLDFVKPTP TLGTKWGVGG TCVNVGCIPK KLMHQASLLG EAVHEAAAYG WNVDEKIKPD WHKLVQSVQN HIKSVNWVTR VDLRDKKVEY...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 37-524aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: QRDYDLLVVG GGSGGLACAK EAAQLGRKVA VVDYVEPSPQ GTRWGLGGTC VNVGCIPKKL MHQAALLGGL IQDAPNYGWE VAQPVPHDWR KMAEAVQNHV KSLNWGHRVQ...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TrxR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TrxR1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TrxR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TrxR1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TrxR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TrxR2. Next,...

Thioredoxin reductase 1 inhibitor 1 (TRi-1) is an irreversible inhibitor of thioredoxin reductase 1 (TrxR1, IC50 = 0.012 µM). It inhibits TrxR1-induced reduction of Trx1 in a cell-free assay (IC50 = 4.3 µM). TRi-1 (10 µM) reduces the mitochondrial oxygen consumption rate in HCT116 colorectal cancer cells. It...

Thioredoxin reductase 2 (TrxR2) is an oxidoreductase encoded by the TXNRD2 gene in humans and a member of the antioxidant thioredoxin system. It exists as a homodimer and contains a dimer interface domain, FAD- and NADPH-binding domains, an N-terminal redox catalytic site, and a C-terminal selenocysteine residue,...

Thioredoxin reductase 1 (TrxR1) is an oxidoreductase encoded by the TXNRD1 gene in humans and a member of the antioxidant thioredoxin system, which is involved in the maintenance of cellular thiol redox homeostasis. It exists as a homodimer and contains a dimer interface domain, FAD- and NADPH-binding domains, an...

Protein function: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. [The UniProt Consortium]

Protein function: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the...