41 products were found matching "K21289"!
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Eganelisib
Item number: TGM-T5432-100mg
Description: Eganelisib (IPI-549) is an inhibitor of PI3Kgamma (IC50 = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). Target: PI3K. Smiles: C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cnn(C)c3)c2c(=O)n1-c1ccccc1. References: De Vera AA1, Gupta P.et...
| Keywords: | IPI-549 |
| Application: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG) |
| CAS | 1693758-51-8 |
| MW: | 528.56 D |
From 42.00€
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TASP0415914
Item number: TGM-T7879-100mg
Description: TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase gamma (PI3Kgamma). T. Target: Akt, PI3K. Smiles: CC(=O)Nc1nc(C)c(s1)-c1nc(no1)N1CCCC(O)C1. References: Oka Y , Yabuuchi T , Oi T , et al. Discovery of...
| Application: | PI3Kgamma inhibitor |
| CAS | 1292300-75-4 |
| MW: | 323.37 D |
From 49.00€
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PIK3CG Protein, Human, Recombinant (His & Myc)
Item number: TGM-TMPH-01857-100ug
Description: PIK3CG Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.4 kDa and the accession number is P48736.
| Keywords: | p120-PI3K, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphatidylinositol... |
| MW: | 35.4 kD |
From 281.00€
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Anti-PIK3CG
Item number: CSB-PA13309A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: PIK3CG. Antigen Species: Human
| Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-p110gamma, Anti-PI3K-gamma, EC=2.7.11.1, Anti-PI3-kinase subunit gamma,... |
| Application: | ELISA, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Anti-PIK3CG
Item number: CSB-PA827787.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIK3CG. Antigen Species: Human
| Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-p110gamma, Anti-PI3K-gamma, EC=2.7.11.1, Anti-PI3-kinase subunit gamma,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Anti-PIK3CG
Item number: CSB-PA877253.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIK3CG. Antigen Species: Human
| Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p120-PI3K, Anti-p110gamma, Anti-PI3K-gamma, EC=2.7.11.1, Anti-PI3-kinase subunit gamma,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic...
Item number: CSB-EP018001HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 828-1073aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: IGIIFKHGDD LRQDMLILQI LRIMESIWET ESLDLCLLPY GCISTGDKIG MIEIVKDATT IAKIQQSTVG NTGAFKDEVL NHWLKEKSPT EEKFQAAVER FVYSCAGYCV...
| Keywords: | PIK3CG, p110gamma, PI3Kgamma, p120-PI3K, PI3K-gamma, EC=2.7.11.1, PI3-kinase subunit gamma, PtdIns-3-kinase subunit gamma,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 35.4 kD |
From 292.00€
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TASP0415914
Item number: Cay41145-1
TASP0415914 is a PI3Kgamma inhibitor (IC50 = 29 nM). It is selective for PI3Kgamma over Akt (IC50 = 294 nM). In vivo, TASP0415914 (30 and 100 mg/kg) reduces ankle redness and swelling in a mouse model of collagen-induced arthritis.Formal Name:...
| Keywords: | N-[5-[3-(3-hydroxy-1-piperidinyl)-1,2,4-oxadiazol-5-yl]-4-methyl-2-thiazolyl]-acetamide |
| Application: | PI3Kgamma inhibitor |
| CAS | 1292300-75-4 |
| MW: | 323.4 D |
From 81.00€
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IPI-549
Item number: Cay26416-1
IPI-549 is an inhibitor of PI3Kgamma (IC50s = 16, 3,200, 3,500, and >8,400 nM for PI3Kgamma, PI3Kalpha, PI3Kbeta, and PI3Kdelta, respectively). It is greater than 100-fold selective for PI3Kgamma over a panel of 468 mutant and nonmutant protein and lipid kinases, including Class II PI3K isoforms, and a panel of 80 G...
| Keywords: | 2-amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]-pyrazolo[1,5-... |
| Application: | PI3Kgamma inhibitor |
| CAS | 1693758-51-8 |
| MW: | 528.6 D |
From 49.00€
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PI3 kinase (p120g), active human recombinant protein
Item number: BPS-40625
Active human p120gamma ( GenBank Accession No. AF327656), full length with N-terminal His tag, MW=131 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Keywords: | PIK3CG, p110gamma, p120-PI3K, PI3Kgamma, PI3K-gamma, PI3-kinase subunit gamma, PtdIns-3-kinase subunit gamma,... |
| Application: | Enzyme kinetics, inhibitor screening |
| MW: | 131 kD |
655.00€
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Anti-PIK3CG
Item number: E-AB-13516.120
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell...
| Keywords: | Anti-PIK3CG, Anti-PI3Kgamma, Anti-p110gamma, Anti-p120-PI3K, Anti-PI3K-gamma, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 89.00€
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CH5132799
Item number: Cay26410-50
CH5132799 is an inhibitor of class I PI3K isoforms (IC50s = 14, 120, 500, and 36 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively). It is selective for these PI3K isoforms over PI3KC2alpha and PI3KC2beta, which are class II PI3Ks, Vps34, a class III PI3K, and mTOR (IC50s = 5,300, >10,000, >10,000,...
| Keywords: | 5-[6,7-dihydro-7-(methylsulfonyl)-2-(4-morpholinyl)-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-pyrimidinamine |
| Application: | PI3K alpha / beta / delta / gamma inhibitor |
| CAS | 1007207-67-1 |
| MW: | 377.4 D |
From 271.00€
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