30 products were found matching "K17718"!

Description: N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent and the major biologically active amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively. Target: Parasite. Smiles: Cl.Cl.CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O. References: Sasi P, et al. In...

Description: N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone , a potent and selective PPARgamma ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl rosiglitazone. Target: Others....

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 27-490aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RKLPPGPTPL PIIGNMLQID VKDICKSFTN FSKVYGPVFT VYFGMNPIVV FHGYEAVKEA LIDNGEEFSG RGNSPISQRI TKGLGIISSN...

An internal standard for the quantification of 6alpha-hydroxy paclitaxel 6alpha-hydroxy Paclitaxel-d5 is intended for use as an internal standard for the quantification of 6alpha-hydroxy paclitaxel (Cay-10009027) by GC- or LC-MS. 6alpha-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent...

N-desethyl Amodiaquine is a primary metabolite of the antimalarial compound aminodiaquine (Cay-15954), produced by the action of cytochrome P450 isoform 2C8. N-desethyl Amodiaquine is highly active against P. falciparum and can synergize with amodiaquine.Formal Name:...

Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide has anticonvulsant activity...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cytochrome P450 2C8 Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway....

N-desmethyl Rosiglitazone is a major metabolite of rosiglitazone (Cay-71740, Cay-71742, Cay-11884), a potent and selective PPARgamma ligand present in formulations that have been used to treat type 2 diabetes. Rosiglitazone is metabolized by the cytochrome P450 (CYP) isoform CYP2C8 to form N-desmethyl...

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to...