30 products were found matching "K16194"!

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EIF2alpha activator 2
EIF2alpha activator 2

Item number: TGM-T62637-2mg

Description: EIF2alpha activator 2 (Compound 1) is a phosphorylated activator of eukaryotic initiation factor 2alpha (eIF2alpha), exhibiting anti-proliferative effects in K562 cells (IC50: 4.79 µM) and PBMC cells (IC50: 10.52 µM). Target: Others. Smiles:...
Application: EIF2AK1/HRI activator
CAS 1501618-04-7
MW: 446.39 D
91.00€ *
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eIF2alpha Activator 2
eIF2alpha Activator 2

Item number: Cay40130-1

eIF2alpha activator 2 is an activator of eukaryotic translation initiation factor 2alpha kinase 1 (EIF2AK1), also known as heme-regulated inhibitor kinase (HRI). It activates HRI and induces eIF2alpha phosphorylation in a surrogate cell-based reporter assay. eIF2alpha activator 2 selectively inhibits the...
Keywords: Eukaryotic Translation Initiation Factor 2 Subunit 1 Activator 2,...
Application: EIF2AK1/HRI activator
CAS 1501618-04-7
MW: 446.4 D
From 67.00€ *
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Anti-EIF2AK1
Anti-EIF2AK1

Item number: CSB-PA002969.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Keywords: Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive...
Application: ELISA, WB, IHC
Host: Rabbit
Species reactivity: human, mouse, monkey
From 126.00€ *
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Hemin chloride
Hemin chloride

Item number: Cay16487-1

Hemin chloride is an oxidized form of heme that inhibits eukaryotic translation initiation factor 2alpha kinase 1 (eIF2alphaK1), a repressor of eIF-2alpha. This alters the initiation of mRNA translation, evoking a wide array of cellular effects. Hemin chloride is used experimentally to induce the expression of heme...
Keywords: (SP-5-13)-chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,8-dipropanoato(4-)-kappaN21, kappaN22, kappaN23,...
Application: EIF2AK1 inhibitor
CAS 16009-13-5
MW: 652 D
From 67.00€ *
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Anti-EIF2AK1
Anti-EIF2AK1

Item number: A302-685A

Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
Keywords: Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 178.00€ *
Review
Anti-EIF2AK1
Anti-EIF2AK1

Item number: A302-686A

Protein function: Inhibits protein synthesis at the translation initiation level, in response to various stress conditions, including oxidative stress, heme deficiency, osmotic shock and heat shock. Exerts its function through the phosphorylation of EIF2S1 at 'Ser- 48' and 'Ser-51', thus preventing its recycling....
Keywords: Anti-HCR, Anti-HRI, Anti-PRO1362, Anti-EIF2AK1, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 178.00€ *
Review
Anti-EIF2AK1
Anti-EIF2AK1

Item number: E-AB-18852.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
Keywords: Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 89.00€ *
Review
Anti-EIF2AK1
Anti-EIF2AK1

Item number: E-AB-52765.120

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Inhibits protein...
Keywords: Anti-HCR, Anti-HRI, Anti-EIF2AK1, Anti-PRO1362, EC=2.7.11.1, Anti-Heme-regulated inhibitor, Anti-Heme-controlled...
Application: WB, ELISA
Host: Rabbit
Species reactivity: human, mouse, rat
From 89.00€ *
Review
Anti-EIF2AK1
Anti-EIF2AK1

Item number: ATA-HPA016496.100

Protein function: Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to various stress conditions (PubMed:32132706, PubMed:32132707). Key activator of the integrated stress response (ISR) required for adaptation...
Keywords: Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive...
Application: ICC, IHC, WB
Host: Rabbit
Species reactivity: human
From 320.00€ *
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NEW
Anti-hri2
Anti-hri2

Item number: CSB-PA007511XA01SXV.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Keywords: Anti-hri2, Anti-SPAC222.07c, EC=2.7.11.1, Anti-Heme-regulated inhibitor 2, Anti-Eukaryotic translation initiation factor...
Application: ELISA, WB
Host: Rabbit
Species reactivity: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
From 1,529.00€ *
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NEW
Anti-hri1
Anti-hri1

Item number: CSB-PA007510XA01SXV.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Keywords: Anti-hri1, EC=2.7.11.1, Anti-SPAC20G4.03c, Anti-Heme-regulated inhibitor 1, Anti-Eukaryotic translation initiation factor...
Application: ELISA, WB
Host: Rabbit
Species reactivity: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
From 1,529.00€ *
Review
Anti-EIF2AK1
Anti-EIF2AK1

Item number: CSB-PA007510LA01HU.100

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: EIF2AK1. Antigen Species: Human
Keywords: Anti-HCR, Anti-hHRI, Anti-PRO1362, Anti-Heme-regulated inhibitor, Anti-Heme-controlled repressor, Anti-Hemin-sensitive...
Application: ELISA, WB, IHC, IF
Host: Rabbit
Species reactivity: human, rat
From 167.00€ *
Review
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