60 products were found matching "K14382"!
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Sodium/glucose cotransporter 2 (SLC5A2)-VLPs, recombinant...
Item number: CSB-MP021679HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-672aa. Protein Length: Full Length. Tag Info: C-terminal Flag-tagged. Target Protein Sequence: MEEHTEAGSA PEMGAQKALI DNPADILVIA AYFLLVIGVG LWSMCRTNRG TVGGYFLAGR SMVWWPVGAS LFASNIGSGH FVGLAGTGAA SGLAVAGFEW NALFVVLLLG WLFAPVYLTA GVITMPQYLR...
| Keywords: | SLC5A2, Na(+)/glucose cotransporter 2, Sodium/glucose cotransporter 2, Solute carrier family 5 member 2, Low affinity... |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 73.9 kD |
From 579.00€
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Empagliflozin
Item number: AG-CR1-3619-M010
White solid. Soluble in DMSO. Slightly soluble in water or ethanol. Antidiabetic agent, Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >,300-fold selectivity over SGLT-1, 4, 5 and 6, SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition...
| Keywords: | Jardiance, BI-10773 |
| Application: | Antidiabetic agent, SGLT2 inhibitor |
| CAS | 864070-44-0 |
| MW: | 450,9 D |
From 77.00€
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Sergliflozin A
Item number: Cay14342-1
Sergliflozin A is an inhibitor of sodium-glucose cotransporter 2 (SGLT2, Ki = 2.39 nM for the human transporter) and an active metabolite of sergliflozin etabonate. It is formed from sergliflozin etabonate by esterases and selectively inhibits SGLT2 over SGLT1 (Ki = 708 nM for the human transporter). Co-infusion of...
| Keywords: | 2[(4methoxyphenyl)methyl]phenyl, beta-D-glucopyranoside |
| Application: | SGLT2 (SLC5A2, sodium/glucose cotransporter) inhibitor, active sergliflozin etabonate metabolite |
| CAS | 360775-96-8 |
| MW: | 376.4 D |
From 67.00€
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Empagliflozin
Item number: TGM-T1766-5mg
Description: Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes. Target: SGLT. Smiles:...
| Keywords: | BI 10773 |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 864070-44-0 |
| MW: | 450.91 D |
From 40.00€
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Remogliflozin
Item number: TGM-T24708-10mg
Description: Remogliflozin is an effective sodium-glucose transporter 2 inhibitor (Kis = 12.4 and 26 nM for human and rat SGLT2, respectively). Target: Others. Smiles: C(C=1C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)=NN(C(C)C)C1C)C3=CC=C(OC(C)C)C=C3. References: Sadurní A, Kehr G, Ahlqvist M, Wernevik J, Sjögren...
| Keywords: | GSK189074, Remogliflozin A, GSK-189074, GSK 189074 |
| Application: | Antidiabetic, SGLT-2 inhibitor |
| CAS | 329045-45-6 |
| MW: | 450.53 D |
From 117.00€
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Sergliflozin etabonate
Item number: TGM-T28757-100mg
Description: Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity. Target: SGLT. Smiles: O(C1=C(CC2=CC=C(OC)C=C2)C=CC=C1)[C@@H]3O[C@H](COC(OCC)=O)[C@@H](O)[C@H](O)[C@H]3O. References: Hussey EK, et al. Multiple-dose pharmacokinetics and...
| Keywords: | GW-869682, GW-869682X, KGT-1251, GW869682X, GW869682, KGT1251 |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 408504-26-7 |
| MW: | 448.46 D |
From 194.00€
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Dapagliflozin-3-O-beta-D-Glucuronide
Item number: TGM-T35619-1mg
Description: Dapagliflozin-3-O-beta-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A9 to...
| Application: | SGLT2 inhibitor |
| CAS | 1351438-75-9 |
| MW: | 585 D |
From 352.00€
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Ertugliflozin
Item number: TGM-T4999-100mg
Description: PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). Target: SGLT. Smiles: CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1. References: Mascitti V, et al. Discovery of a clinical candidate from the...
| Keywords: | PF-04971729, MK-8835 |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 1210344-57-2 |
| MW: | 436.88 D |
From 45.00€
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Tofogliflozin (hydrate)
Item number: TGM-T5016-100mg
Description: Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively. Target: ROS, Reactive Oxygen Species, SGLT. Smiles:...
| Keywords: | Tofogliflozin hydrate, CSG-452 hydrate |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 1201913-82-7 |
| MW: | 404.45 D |
From 40.00€
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5-Methylcytidine
Item number: TGM-T5912-100mg
Description: 5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms. Target: Endogenous Metabolite. Smiles: Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)nc1N. References: Transcriptome-wide mapping of 5-methylcytidine RNA...
| Application: | DNA methylation studies |
| CAS | 2140-61-6 |
| MW: | 257.24 D |
From 48.00€
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Bexagliflozin
Item number: TGM-T7217-100mg
Description: Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2 and 5.6 µM for human SGLT1. Target: SGLT. Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCOC3CC3)cc2)c1. References: Zhang W , Welihinda A ,...
| Keywords: | EGT0001442, THR-1442, EGT1442 |
| Application: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 1118567-05-7 |
| MW: | 464.94 D |
From 65.00€
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T-1095
Item number: TGM-T9590-100mg
Description: T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2). Target: transporter, SGLT. Smiles: COC(=O)OC[C@H]1O[C@@H](Oc2cc(C)cc(O)c2C(=O)CCc2ccc3occc3c2)[C@H](O)[C@@H](O)[C@@H]1O. References: Adachi T, et...
| Application: | SGLT1 / SGLT2 inhibitor |
| CAS | 209746-59-8 |
| MW: | 516.49 D |
From 48.00€
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