30 products were found matching "K14158"!

Description: Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglycemic activity. Target: SGLT. Smiles: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](SC)[C@@H](O)[C@H](O)[C@H]2O)cc1. References: Zambrowicz B, et al. Clin...

Description: Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . Target: ATPase, SGLT. Smiles: C(CCC1=CC=C(O)C=C1)(=O)C2=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C(O)C=C2O. References: Taton J, et al. Endokrynol Pol, 2010, 61(3), 303-310.

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: SLC5A1. Antigen Species: Human

Sodium-glucose cotransporter 1 (SGLT1) is a high affinity, low capacity transporter abundant in the small intestine, with some expression in the kidney as well. SGLT2 is a low affinity, high capacity transporter in the kidney that accounts for approximately 90% of glucose reabsorption into the blood stream....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sodium/glucose cotransporter 1, also known as NAGT or SGLT1 is a protein that in humans is encoded by the SLC5A1 gene. This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary...

Sotagliflozin is an inhibitor of sodium-glucose cotransporters (SGLTs, IC50s = 36 and 1.8 nM for human SGLT1 and SGLT2, respectively). It increases plasma glucagon-like peptide 1 (GLP-1) and peptide YY (PYY) levels, as well as glucose levels in the small intestine, cecum, and colon, in mice when administered at a...

Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Solute carrier family 5 (sodium/glucose cotransporter), member 1 Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1....

Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...

Protein function: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in...

Licogliflozin (mixed isomers) is a mixture of isomers of the sodium-glucose cotransporter 1 (SGLT1) and SGLT2 inhibitor licogliflozin.Formal Name: (2S,3S,4S,5R,6R)-2-(3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-ethylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS Number: 2730989-98-5. Synonyms:...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SGLT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SGLT1. Next,...