- Search results for K13762
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95 products were found matching "K13762"!
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Item number: ABS-KC-207.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide- generated cGMP (PubMed:15489334). [The UniProt...
Keywords: | Anti-cGMP-specific 3', Anti-5'-cyclic phosphodiesterase, Anti-cGMP-binding cGMP-specific phosphodiesterase, Anti-CGB-PDE,... |
Host: | Mouse |
Species reactivity: | human |
From 232.00€
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Item number: ABS-KC-208.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide- generated cGMP (PubMed:15489334). [The UniProt...
Keywords: | PDE5A Antibody |
Host: | Mouse |
Species reactivity: | human |
From 232.00€
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Item number: ABS-KC-219.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide- generated cGMP (PubMed:15489334). [The UniProt...
Keywords: | Anti-cGMP-specific 3', Anti-5'-cyclic phosphodiesterase, Anti-cGMP-binding cGMP-specific phosphodiesterase, Anti-CGB-PDE,... |
Application: | IP |
Host: | Mouse |
Species reactivity: | human |
From 206.00€
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Item number: ABS-KC-220.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide- generated cGMP (PubMed:15489334). [The UniProt...
Keywords: | Anti-cGMP-specific 3', Anti-5'-cyclic phosphodiesterase, Anti-cGMP-binding cGMP-specific phosphodiesterase, Anti-CGB-PDE,... |
Host: | Mouse |
Species reactivity: | human |
From 232.00€
*
Item number: ABS-KC-615.100
Protein function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide- generated cGMP (PubMed:15489334). [The UniProt...
Keywords: | Anti-cGMP-specific 3', Anti-5'-cyclic phosphodiesterase, Anti-cGMP-binding cGMP-specific phosphodiesterase, Anti-CGB-PDE,... |
Host: | Mouse |
Species reactivity: | human |
From 232.00€
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Item number: TGM-T1398-10mg
Description: Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby...
Keywords: | Cialis, IC-351 |
Application: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
CAS | 171596-29-5 |
MW: | 389.4 D |
From 33.00€
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Item number: TGM-T15381-100mg
Description: Gisadenafil (UK-369003), a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM, prevents the degradation of cGMP. Target: PDE. Smiles: C(C)C1=C2C(=NN1CCOC)C(=O)N=C(N2)C3=C(OCC)N=CC(S(=O)(=O)N4CCN(CC)CC4)=C3. References: Rawson DJ, et al. The discovery of UK-369003, a novel PDE5...
Keywords: | UK-369003 |
Application: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
CAS | 334826-98-1 |
MW: | 519.62 D |
From 194.00€
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Item number: TGM-T36444-1g
Description: Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1It is also a potential impurity found in commercial preparations of sildenafil. Target: Others. Smiles: CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(Cl)(=O)=O. References:...
Application: | Sildenafil synthesis intermediate |
CAS | 139756-22-2 |
MW: | 410.88 D |
From 93.00€
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Item number: TGM-T28360-10mg
Description: PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy. Target: PDE. Smiles: C(NS(C)(=O)=O)(=O)C=1C=2C(=C(NC3=CC(C)=CC=N3)N=C(N(CC)C)N2)N(CCOCC)N1. References: Scheele W, Diamond S, Gale J, Clerin V, Tamimi N, Le V, Walley R, Grover-Páez...
Keywords: | PF4634817, PF 00489791, PF-4634817, PF 4634817, PF00489791 |
Application: | PDE5A inhibitor |
CAS | 853003-48-2 |
MW: | 476.55 D |
From 103.00€
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Item number: TGM-T2855-100mg
Description: Icariin (Ieariline) belongs to the flavonol glycoside group of natural products, can inhibit PDE5 and PDE4 activity (IC50=432/73.50 µM), is also a PPARalpha activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism. Target:...
Keywords: | Ieariline |
Application: | PDE5 inhibitor, Metabolic studies |
CAS | 489-32-7 |
MW: | 676.66 D |
From 34.00€
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Item number: TGM-T4097-100mg
Description: Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. Target: PDE. Smiles: O.O.O.Cl.CCCc1nc(C)c2n1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(CC)CC1. References: Saenz de Tejada I, et al. Int J Impot Res, 2001, 13(5), 282-290.
Keywords: | Vardenafil HCl Trihydrate, BAY38-9456 |
Application: | PDE5 inhibitor |
CAS | 330808-88-3 |
MW: | 579.11 D |
From 40.00€
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Item number: TGM-T41108-1mg
Description: Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor. Target: Others. Smiles: CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)C(=O)CN1CCN(C)CC1. References: Samuel R Gratz, et al. Accurate Mass Measurement Using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry...
Application: | Sildenafil derivative |
CAS | 949091-38-7 |
MW: | 452.55 D |
From 295.00€
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