138 products were found matching "K13241"!
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L-NIL (hydrochloride)
Item number: Cay80310-10
L-NIL is a relatively selective inhibitor of iNOS. It exhibits IC50 values of 0.4-3.3 µM for iNOS as opposed to 8-38 and 17-92 µM for eNOS and nNOS, respectively. L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection...
| Keywords: | N6-(1-iminoethyl)-L-lysine, dihydrochloride |
| Application: | iNOS inhibitor |
| CAS | 159190-45-1 |
| MW: | 260.2 D |
From 54.00€
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iNOS inhibitor-10
Item number: TGM-T72638-100mg
Description: iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1]. Target: NO Synthase. Smiles: CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC(=CC=C2)CN=C(C3=CC=CC=C3)N
| Application: | iNOS inhibitor |
| CAS | 2918773-63-2 |
| MW: | 393.5 D |
From 1,491.00€
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2-Iminobiotin
Item number: TGM-T7206-100mg
Description: 2-Iminobiotin (Guanidinobiotin) is a cyclic guanidino analog of biotin and serves as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS), with Ki values of 21.8 µM for mouse iNOS and 37.5 µM for rat nNOS. Target: NO Synthase, NOS. Smiles:...
| Keywords: | 2-IMINOBIOTIN HYDROBROMIDE, Guanidinobiotin |
| Application: | iNOS / nNOS inhibitor |
| CAS | 13395-35-2 |
| MW: | 243.33 D |
From 77.00€
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2-Iminobiotin hydrobromide
Item number: TGM-T7206L-10mg
Description: 2-Iminobiotin hydrobromide (Guanidinobiotin) is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS, Ki of 21.8 and 37.5 µM for mouse iNOS and rat nNOS, respectively). Target: NO Synthase, NOS. Smiles:...
| Keywords: | Guanidinobiotin |
| Application: | Guanidine-modified biotin derivative, iNOS and nNOS inhibitor |
| CAS | 76985-52-9 |
| MW: | 324.24 D |
From 30.00€
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Diphenyleneiodonium chloride
Item number: TGM-T7191-100mg
Description: Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 µM, respectively),and displays broad-spectrum bactericidal activity. Target: TRP/TRPV Channel, NADPH, Reactive Oxygen Species, NOS. Smiles: [Cl-].[I+]1c2ccccc2-c2ccccc12. References:...
| Keywords: | DPI |
| Application: | iNOS inhibitor, eNOS inhibitor |
| CAS | 4673-26-1 |
| MW: | 314.55 D |
From 38.00€
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Cynarin
Item number: TGM-T6S1529-10mg
Description: Cynarin (1,5-Dicaffeoylquinic acid) has neuroprotective, and antioxidant effects, it can inhibition of GSK3beta as well as the modulation of Bcl-2/Bax. Target: Antioxidant, Antiviral, Influenza Virus, Reactive Oxygen Species. Smiles:...
| Keywords: | Cynarine, Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-,... |
| Application: | Bioactive polyphenol |
| CAS | 30964-13-7 |
| MW: | 516.45 D |
From 39.00€
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S-(2-aminoethyl) Isothiourea (dihydrobromide)
Item number: TGM-T7543-1mL
Description: S-(2-aminoethyl) Isothiourea (dihydrobromide) is a non-selective inhibitor of all NOS isoforms. For human nNOS, eNOS, and iNOS, the Ki values are 1.8, 2.1, and 0.59 µM, respectively. Target: NOS. Smiles: Br.Br.NCCSC(N)=N. References: Garvey E P , Oplinger J A , Tanoury G J , et al. Potent and selective...
| Application: | NOS inhibitor |
| CAS | 56-10-0 |
| MW: | 281.02 D |
From 38.00€
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6-Biopterin
Item number: TGM-T7597-100mg
Description: 6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. Target: Endogenous Metabolite, NO Synthase, NOD. Smiles: C[C@H](O)[C@H](O)c1cnc2nc(N)nc(O)c2n1. References: Schallreuter K U , Buttner G , Pittelkow M R , et al. Cytotoxicity of 6-Biopterin to Human Melanocytes[J]. Biochemical &...
| Keywords: | L-Biopterin |
| Application: | Metabolic studies |
| CAS | 22150-76-1 |
| MW: | 237.22 D |
From 31.00€
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L-NIL dihydrochloride
Item number: TGM-T25749-100mg
Description: L-NIL HCl is a relatively selective iNOS inhibitor (IC50s: 0.4-3.3, 8-38, and 17-92 µM for iNOS, eNOS, and nNOS). L-NIL effectively inhibits iNOS both in vitro and in vivo. L-NIL has been used to demonstrate a critical role for iNOS in the immune response to infection by the protozoan L. major. Target:...
| Keywords: | L-NIL HCl, N-Iminoethyl-L-lysine dihydrochloride |
| Application: | iNOS inhibitor |
| CAS | 159190-45-1 |
| MW: | 260.16 D |
From 96.00€
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NOS-IN-1
Item number: TGM-T21700-1mg
Description: NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 µM, 0.2 µM, and 1.1µM for human iNOS (hiNOS), hnNOS and heNOS, respectively. Target: NOS. Smiles: CC(CCN1)CC1=N.CC(O)=O. References: R K Webber, et al....
| Keywords: | 2-Imino-4-methylpiperidine (acetate) |
| Application: | NOS inhibitor |
| CAS | 165383-72-2 |
| MW: | 172.22 D |
From 58.00€
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Cindunistat HCl maleate
Item number: TGM-T30939-25mg
Description: Cindunistat( PHA-728669F, PF-00572986, PHA-84250, SD-6010, and SC-084250) is a potent and oral selective iNOS inhibitor which is expected to be used in patients with symptomatic osteoarthritis of the knee. Target: Others. Smiles:...
| Keywords: | SD 6010, PHA 728669F, SD6010 PF-00572986, PHA-728669F, SD-6010, PHA728669F |
| Application: | Targets nitric-oxide synthase, inducible [EC:1.14.13.39] (NOS2) |
| CAS | 753491-31-5 |
| MW: | 591.14 D |
1,491.00€
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1400W dihydrochloride
Item number: TGM-T3491-100mg
Description: 1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS). Target: NO Synthase, NOS. Smiles: Cl.Cl.CC(=N)NCc1cccc(CN)c1. References: Garvey EP, et al. J Biol Chem. 199, 272(8):4959-63.
| Keywords: | 1400W 2HCl, N-(3-(Aminomethyl)benzyl)acetamidine |
| Application: | iNOS inhibitor |
| CAS | 214358-33-5 |
| MW: | 250.17 D |
From 43.00€
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