34 products were found matching "K12344"!

Description: Finasteride-d9 is a deuterated compound of Finasteride. Finasteride has a CAS number of 98319-26-7. Finasteride is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM. Smiles:...

Description: Elaiophylin (Salbomycin) shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 µM and 0.45 µM, respectively. Target: Autophagy, Others. Smiles:...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-71aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-KSI-tagged. Target Protein Sequence: KPSGYGKHTE SLKPAATRLP ARAAWFLQEL PSFAVPAGIL ARQ. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a....

Finasteride is a 4-azasteroid competitive inhibitor of 5alpha-reductase type II (IC50 = 4.2 nM) and a derivative of testosterone. It is 100-fold selective for 5alpha-reductase type II over type I. Finasteride (10 µM) does not affect the growth of androgen-refractory PC3 prostate cancer cells but increases the...

Antibiotic, Active against Gram-positive bacteria, protozoa and tumors, Testosterone 5alpha-reductase inhibitor, Nitric oxide synthase (NOS) inhibitor, Immunosuppressive, Enhances the antifungal activity of rapamycin. Isolated from Streptomyces sp. MT-1.

White to off-white solid. Soluble in DMSO, DMF, ethanol or methanol. Sparingly soluble in water. Potent, specific and competitive inhibitor of type II 5alpha-reductase (enzyme which converts testosterone to the more potent 5alpha-dihydrotestosterone), Anticancer compound, Apoptosis modulator, Enhances the action of...

Pantoprazole-d6 is intended for use as an internal standard for the quantification of pantoprazole (Cay-21345) by GC- or LC-MS. Pantoprazole is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles with an IC50 value of 6.8 µM. It reduces basal gastric acid secretion in...

Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. [The UniProt Consortium]

Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. [The UniProt Consortium]

5-alpha-Reductase inhibitor.

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steroid 5 alpha-reductase 2 Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids....

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steroid-5-alpha-reductase, alpha polypeptide 2 Protein function: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding...