112 products were found matching "K11988"!
No results were found for the filter!
Sonic HedgeHog, human recombinant (rHuSHH)
Item number: 97290.25
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
| Keywords: | SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5 |
| Application: | Cell culture |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 19683 D |
From 100.00€
*
Jervine
Item number: TGM-T3363-100mg
Description: The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated...
| Keywords: | 11-Ketocyclopamine, Iervin, Jerwiny |
| Application: | Sonic hedgehog pathway inhibitor, birth defect inducer |
| CAS | 469-59-0 |
| MW: | 425.6 D |
From 63.00€
*
HhAntag
Item number: TGM-T3460-100mg
Description: HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway with the anti-tumor activity. Target: Smo, Hedgehog/Smoothened. Smiles: COc1cc(OC)cc(c1)C(=O)Nc1ccc(Cl)c(c1)-c1nc2cc(ccc2[nH]1)N(C)C. References: Actis, Marcelo, Connelly,...
| Application: | Sonic Hedgehog (Shh) pathway inhibitor |
| CAS | 496794-70-8 |
| MW: | 450.92 D |
From 62.00€
*
SHH Protein, Human, Recombinant
Item number: TGM-TMPJ-01127-10ug
Description: SHH Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19 KDa and the accession number is Q15465.
| Keywords: | SHH, HHG-1, Sonic Hedgehog Protein |
| MW: | 19 kD |
From 128.00€
*
SHH Protein, Human, Recombinant (C24II)
Item number: TGM-TMPJ-01128-10ug
Description: SHH Protein, Human, Recombinant (C24II) is expressed in E. coli expression system. The predicted molecular weight is 20 KDa and the accession number is Q15465.
| Keywords: | HHG-1, Sonic Hedgehog Protein, SHH |
| MW: | 20 kD |
From 142.00€
*
SHH Protein, Mouse, Recombinant
Item number: TGM-TMPJ-01170-10ug
Description: SHH Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20 KDa and the accession number is Q62226.
| Keywords: | SHH, HHG-1, Sonic Hedgehog Protein |
| MW: | 20 kD |
From 128.00€
*
SHH Protein, Mouse, Recombinant (C25II)
Item number: TGM-TMPJ-01171-10ug
Description: SHH Protein, Mouse, Recombinant (C25II) is expressed in E. coli expression system. The predicted molecular weight is 18-20 KDa and the accession number is Q62226.
| Keywords: | Sonic Hedgehog Protein, HHG-1, SHH |
| MW: | 20 kD |
From 128.00€
*
SHH Protein, Human, Recombinant (aa 198-462, His)
Item number: TGM-TMPY-02832-100ug
Description: SHH Protein, Human, Recombinant (aa 198-462, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29 kDa and the accession number is Q15465.
| Keywords: | TPTPS, HHG1, HLP3, SMMCI, MCOPCB5, HPE3, TPT, Sonic hedgehog |
| MW: | 29 kD |
538.00€
*
SHH Protein, Human, Recombinant (aa 1-197, His)
Item number: TGM-TMPY-02905-100ug
Description: SHH Protein, Human, Recombinant (aa 1-197, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q15465.
| Keywords: | HHG1, SMMCI, MCOPCB5, HPE3, TPT, HLP3, Sonic hedgehog, TPTPS |
| MW: | 21 kD |
From 212.00€
*
SHH Protein, Mouse, Recombinant (His)
Item number: TGM-TMPY-03345-100ug
Description: Sonic Hedgehog Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is Q62226.
| Keywords: | sonic hedgehog, M100081, 9530036O11Rik, Dsh, Hxl3, Hhg1, Hx |
| MW: | 21 kD |
From 345.00€
*
Robotnikinin
Item number: TGM-T26110-100mg
Description: Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2. Target: Others. Smiles: O=C1O[C@@H](CNC(=O)[C@H](CC(NCC2=CC=C(Cl)C=C2)=O)C\C=C\CC1)C3=CC=CC=C3. References: Hitzenberger M, Schuster D, Hofer TS. The...
| Application: | Shh inhibitor |
| CAS | 1132653-79-2 |
| MW: | 454.95 D |
From 1,820.00€
*
SHH Protein (Trx Tag) (recombinant mouse)
Item number: E-PDEM100126.100
Sequence: Cys25-Gly198. Fusion tag: N-Trx Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 39 kDa. Protein function: Protein function: [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol...
| Keywords: | Hhg1, Recombinant Mouse SHH Protein(Trx Tag) |
| Expressed in: | E.coli |
| Origin: | mouse |
From 304.00€
*