118 products were found matching "K11722"!

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...

A1874 is a proteolysis-targeting chimera (PROTAC) that contains (+)-JQ1 (Cay-11187), an inhibitor of bromodomain and extra terminal domain (BET) bromodomains, conjugated to RG7388 (Cay-21532), an inhibitor of the MDM2-p53 interaction. It induces the degradation of bromodomain-containing protein 4 (BRD4), decreases...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 150-200aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: AEALEKLFLQ KINELPTEET EIMIVQAKGR GRGRKETGTA KPGVSTVPNT T. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological...

AT-1 is a proteolysis-targeting chimera (PROTAC) that contains the bromodomain and extra terminal (BET) domain-containing protein inhibitor (+)-JQ1 (Cay-11187) conjugated to PROTAC building block VH ligand 032 (Cay-39982). It selectively degrades bromodomain-containing protein 4 (BRD4) over BRD3 and BRD2 in HeLa...

Recombinant human BRD4 protein with C-terminal human Fc tag. BRD4(Met1-Phe1362) hFc(Glu99-Ala330), Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated...

Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: BRD4. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: BRD4. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: BRD4. Antigen Species: Human

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...