125 products were found matching "K11647"!
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ACBI1
Item number: Cay36612-1
ACBI1 is a proteolysis-targeting chimera (PROTAC) composed of a ligand for BRM, also known as SMARCA2, BRG1, also known as SMARCA4, and polybromo-1D (PBRM1), which are components of switch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complexes, conjugated to a von Hippel-Lindau (VHL) E3 ligase ligand. It...
| Keywords: | (2S,4R)-N-(2-(2-(4-((4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)phenoxy)ethoxy)-4-(4-methylthiazol... |
| Application: | BRM / BRG1 / PBRM1 degradation driving PROTAC |
| CAS | 2375564-55-7 |
| MW: | 936.1 D |
From 98.00€
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FHD-286
Item number: LKT-F130280.1
FHD-286 is a BRG1/BRM ATPase inhibitor, which is associated with tumor development and progression. SMILES: CC1CN(CC(O1)C)C2=CC=CC(=N2)C3=CSC(=N3)NC(=O)C(COC)NC(=O)C4=CN(C=C4)S(=O)(=O)C
| Keywords: | FHD286,... |
| Application: | BRG1/BRM ATPase inhibitor |
| CAS | 2671128-05-3 |
| MW: | 562.66 D |
From 275.00€
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Probable global transcription activator SNF2L2 (SMARCA2),...
Item number: CSB-MP021799HU4.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1350-1520aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: RNVDKDPAKE DVEKAKKRRG RPPAEKLSPN PPKLTKQMNA IIDTVINYKD RCNVEKVPSN SQLEIEGNSS GRQLSEVFIQ LPSRKELPEY YELIRKPVDF KKIKERIRNH KYRSLGDLEK DVMLLCHNAQ...
| Keywords: | hBRM, BAF190B, EC=3.6.4.-, SNF2-alpha, Protein brahma homolog, BRG1-associated factor 190B, ATP-dependent helicase... |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 47.4 kD |
From 371.00€
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Anti-SMARCA4
Item number: ABS-KC-6076.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Keywords: | Anti-Transcription activator BRG1, Anti-ATP-dependent helicase SMARCA4, Anti-BRG1-associated factor 190A, Anti-BAF190A,... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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Anti-SMARCA4
Item number: ABS-KC-6170.100
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a...
| Keywords: | Anti-Transcription activator BRG1, Anti-ATP-dependent helicase SMARCA4, Anti-BRG1-associated factor 190A, Anti-BAF190A,... |
| Host: | Mouse |
| Species reactivity: | human, mouse |
From 232.00€
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Anti-ABCB5, clone CL13779
Item number: ATA-AMAb91895.25
Monoclonal Antibody against Human SMARCA4, Clone ID: CL13779, Gene description: Swi/snf related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, Alternative Gene Names: BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, Validated applications: ICC, WB, Uniprot...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | WB, ICC |
| Host: | Mouse |
| Species reactivity: | human |
320.00€
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Anti-ABCB5, clone CL13783
Item number: ATA-AMAb91897.25
Monoclonal Antibody against Human SMARCA4, Clone ID: CL13783, Gene description: Swi/snf related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, Alternative Gene Names: BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, Validated applications: IHC, Uniprot ID:...
| Keywords: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
320.00€
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BRM/BRG1 ATP Inhibitor-2
Item number: TGM-T60032-100mg
Description: BRM/BRG1 ATP Inhibitor-2 is a BRG1/BRM ATPase inhibitor, suitable for studies on the treatment of BAF-related disorders. Target: Epigenetic Reader Domain. Smiles: CSCC[C@H](NC(=O)c1cccnc1)C(=O)Nc1nc(cs1)-c1ccccc1. References: Neville John ANTHONY, et al. Compounds and uses thereof. WO2019152437A1.
| Application: | SMARCA2A/SMARCA4 ATPase inhibitor |
| CAS | 2368900-77-8 |
| MW: | 412.53 D |
From 57.00€
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BRM/BRG1 ATP Inhibitor-3
Item number: TGM-T72257-100mg
Description: BRM/BRG1 ATP Inhibitor-3 is a potent inhibitor targeting both BRM and BRG1 components of the BAF complex, with IC50 values of 10.4 nM for BRM and 19.3 nM for BRG1, and holds potential for research in cancer and BAF complex-related disorders. Target: Others. Smiles:...
| Application: | SMARCA2A/SMARCA4 ATPase inhibitor |
| CAS | 2368901-31-7 |
| MW: | 503.64 D |
From 1,520.00€
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BRM/BRG1 ATP Inhibitor-4
Item number: TGM-T72258-100mg
Description: BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders. Target: Others. Smiles: N(C(CNC(=O)C1=CN(C(C)(C)C)C=C1)=O)C2=NC(C=3N=C(C=CC3)N4C[C@@H](C)O[C@@H](C)C4)=CS2
| Application: | SMARCA2A/SMARCA4 ATPase inhibitor |
| CAS | 2422030-94-0 |
| MW: | 496.62 D |
From 1,671.00€
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PFI-3
Item number: TGM-T6939-100mg
Description: PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer. Target: Epigenetic Reader Domain. Smiles: [H][C@@]12CN(c3ccccn3)[C@@]([H])(CN1\C=C\C(=O)c1ccccc1O)C2. References: Structural Genomics Consortium...
| Keywords: | PFI 3 |
| Application: | Bromodomain SMARCA4 / PB1 probe |
| CAS | 1819363-80-8 |
| MW: | 321.37 D |
From 33.00€
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SMARCA4 Protein, Human, Recombinant (His)
Item number: TGM-TMPH-00841-100ug
Description: SMARCA4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.1 kDa and the accession number is P51532.
| Keywords: | BRG1-associated factor 190A, SNF2-beta, ATP-dependent helicase SMARCA4, Mitotic growth and transcription activator,... |
| MW: | 37.1 kD |
From 198.00€
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