45 products were found matching "K11204"!

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L-Buthionine-(S,R)-Sulfoximine
L-Buthionine-(S,R)-Sulfoximine

Item number: Cay14484-250

L-Buthionine-(S,R)-sulfoximine is an irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki = 25 µM). It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC50s = 4.9, 18, 8.5, and 26.5 µM, respectively). L-Buthionine-(S,R)-sulfoximine (100µM)...
Keywords: BSO, NSC 326231, 2S-amino-4-(S-butylsulfonimidoyl)-butanoic acid
Application: Oxidative stress inducer
CAS 83730-53-4
MW: 222.3 D
From 111.00€ *
Review
Glutamate--cysteine ligase catalytic subunit (Gclc), recombinant mouse
Glutamate--cysteine ligase catalytic subunit (Gclc),...

Item number: CSB-EP009321MO.1

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-637aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MGLLSQGSPL SWEETQRHAD HVRRHGILQF LHIYHAVKDR HKDVLKWGDE VEYMLVSFDH ENRKVQLLLN GGDVLETLQE KGERTNPNHP TLWRPEYGSY MIEGTPGQPY GGTMSEFNTV EANMRKRRKE...
Keywords: Gclc, Glclc, Gamma-ECS, EC=6.3.2.2, GCS heavy chain, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase...
Application: Activity not tested
Expressed in: E.coli
Origin: mouse
MW: 79.5 kD
From 247.00€ *
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L-BUTHIONINE-(S,R)-SULFOXIMINE
L-BUTHIONINE-(S,R)-SULFOXIMINE

Item number: TGM-T5371-100mg

Description: L-Buthionine-(S,R)-sulfoximine, a cell-permeable and irreversible inhibitor of gamma-glutamylcysteine synthetase (Ki <100 µM), induces oxidative stress in cells by depleting GSH. Target: Ferroptosis, Others. Smiles: CCCCS(=N)(=O)CC[C@H](N)C(O)=O. References: Marengo B, et al. Mechanisms of BSO...
Keywords: L-Butionine sulfoximine
Application: Oxidative stress inducer
CAS 83730-53-4
MW: 222.31 D
From 34.00€ *
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DL-Buthionine-(S,R)-sulfoximine
DL-Buthionine-(S,R)-sulfoximine

Item number: TGM-T7708-25mg

Description: DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of gamma-glutamylcysteine synthetase used for the treatment of solid tumors. Target: Ferroptosis, Others. Smiles: CCCCS(=N)(=O)CCC(N)C(O)=O. References: Arrick, B. A . Inhibition of glutathione synthesis as a chemotherapeutic...
Keywords: Butionine sulfoximine, NSC 381100, D,L-Buthionine-(S,R)-sulfoximine
Application: gamma-glutamylcysteine synthetase inhibitor
CAS 5072-26-4
MW: 222.31 D
From 31.00€ *
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Anti-GCLC
Anti-GCLC

Item number: CSB-PA002665.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Keywords: Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: ELISA, WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 126.00€ *
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D,L-Buthionine-(S,R)-Sulfoximine
D,L-Buthionine-(S,R)-Sulfoximine

Item number: Cay23691-250

D,L-Buthionine-(S,R)-sulfoximine is an inhibitor of gamma-glutamylcysteine synthetase that induces 100% inhibition at a concentration of 10 µM in an enzyme assay. It is selective for gamma-glutamylcysteine synthetase, lacking activity at glutamine synthetase at concentrations up to 500 µM....
Keywords: NSC 381100, 2-amino-4-(S-butylsulfonimidoyl)-butanoic acid
Application: gamma-glutamylcysteine synthetase inhibitor
CAS 5072-26-4
MW: 222.3 D
From 94.00€ *
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Human GCLC ELISA Kit
Human GCLC ELISA Kit

Item number: G-HUFI01282.96

Application: ELISA
Species reactivity: human
641.00€ *
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Anti-GCLC
Anti-GCLC

Item number: NSJ-R30565

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate--cysteine ligase catalytic subunit, is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of...
Keywords: Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: WB, IHC (paraffin)
Host: Rabbit
Species reactivity: human, mouse, rat
772.00€ *
Review
Anti-GCLC
Anti-GCLC

Item number: NSJ-R31614

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate-cysteine ligase catalytic subunit is an enzyme that in humans is encoded by the GCLC gene. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two...
Keywords: Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: WB, IHC (paraffin)
Host: Rabbit
Species reactivity: human, rat
772.00€ *
Review
Anti-GCLC
Anti-GCLC

Item number: NSJ-F41799-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit,...
Keywords: Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: WB, IHC, IF, FC, ELISA
Host: Rabbit
Species reactivity: human
From 350.00€ *
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Anti-GCLC
Anti-GCLC

Item number: ARG58109.100

Keywords: Anti-GLCL, Anti-GCLC, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: WB
Host: Rabbit
Species reactivity: mouse, rat
658.00€ *
Review
Anti-GCLC
Anti-GCLC

Item number: NSJ-F46551-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit,...
Keywords: Anti-GCLC, Anti-GLCL, Anti-Gamma-ECS, EC=6.3.2.2, Anti-GCS heavy chain, Anti-Gamma-glutamylcysteine synthetase,...
Application: WB, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 350.00€ *
Review
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