94 products were found matching "K11126"!
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Anti-Telomerase (hTERT Catalytic Unit)
Item number: 600-401-252
Protein function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Keywords: | Anti-TP2, Anti-TERT, Anti-EST2, Anti-HEST2, EC=2.7.7.49, Anti-Telomerase catalytic subunit, Anti-Telomerase-associated... |
| Application: | ELISA, IHC, IFM, IP, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 180.00€
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TMPyP4 tosylate
Item number: TGM-T13174-100mg
Description: TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and telomerase inhibitor that exhibits antitumor effects in osteosarcoma cell lines. Target: DNA/RNA Synthesis, Telomerase. Smiles:...
| Keywords: | TMP 1363 |
| Application: | G-quadruplex stabilizer, telomerase inhibitor |
| CAS | 36951-72-1 |
| MW: | 1363.6 D |
From 34.00€
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Cyclogalegenin
Item number: TGM-T3333-100mg
Description: Cyclogalegenin (Astramembrangenin) is able to elongate telomeres, resulting in increased lifespan of the animals. Target: Telomerase. Smiles: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O)C3)(C(C)(C)[C@@H](O)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@@]6(C)O[C@@H]([C@@](C)(C)O)CC6)[H])[H]. References: de Jesus...
| Keywords: | Cyclogalegigenin, Astramembrangenin, Cyclogalagenin, Cycloastragenol |
| Application: | Reported telomerase activator |
| CAS | 84605-18-5 |
| MW: | 490.71 D |
From 31.00€
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Costunolide
Item number: TGM-T2902-100mg
Description: Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. Target: Endogenous Metabolite, Apoptosis, Telomerase. Smiles: [H][C@]12OC(=O)C(=C)[C@]1([H])CC\C(C)=C\CC\C(C)=C\2. References: Choi SH, et al, Cancer Lett, 2005, 227(2), 153-162.
| Keywords: | Costunolid, (+)-Costunolide, Costus lactone, NSC 106404 |
| Application: | Apoptosis inducer |
| CAS | 553-21-9 |
| MW: | 232.32 D |
From 51.00€
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beta-Rubromycin
Item number: TGM-T35428-1mg
Description: beta-Rubromycin is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities.1 It inhibits the growth of HMO2, KATO-III, and MCF-7 cells with GI50 values of 0.5, 0.84, and <0.1 µM, respectively. beta-rubromycin inhibits HIV-1 reverse transcriptase activity by...
| Application: | Human telomerase inhibitor, HIV-1 reverse transcriptase inhibitor |
| CAS | 27267-70-5 |
| MW: | 536.445 D |
From 214.00€
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MST-312
Item number: TGM-T41290-10mg
Description: MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM). Target: Telomerase. Smiles: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O. References: Ameri Z, et al....
| Keywords: | Telomerase Inhibitor IX |
| Application: | Telomerase inhibitor |
| CAS | 368449-04-1 |
| MW: | 380.35 D |
From 32.00€
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RHPS4
Item number: TGM-T6967-100mg
Description: RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar. Target: Apoptosis, Telomerase. Smiles: COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23. References: Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33.
| Keywords: | RHPS 4 methosulfate, NSC714187 |
| Application: | Telomerase inhibitor |
| CAS | 390362-78-4 |
| MW: | 458.48 D |
From 40.00€
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TERT Protein, Human, Recombinant (His)
Item number: TGM-TMPH-02186-100ug
Description: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the...
| Keywords: | HEST2, Telomerase-associated protein 2, Telomerase catalytic subunit, TERT, Telomerase reverse transcriptase |
| MW: | 22.7 kD |
From 237.00€
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TRET Protein, Mouse, Recombinant (His & SUMO)
Item number: TGM-TMPH-02926-100ug
Description: TRET Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.1 kDa and the accession number is O70372.
| Keywords: | Tert, Telomerase reverse transcriptase, Telomerase catalytic subunit |
| MW: | 54.1 kD |
From 359.00€
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6-Thio-2'-Deoxyguanosine
Item number: TGM-T6746-100mg
Description: 6-Thio-2'-Deoxyguanosine (beta-TGdR) is a nucleoside analog and telomerase substrate. Target: DNA/RNA Synthesis, Others. Smiles: Nc1nc(=S)c2ncn([C@H]3C[C@H](O)[C@@H](CO)O3)c2[nH]1. References: Mender I, et al. Cancer Discov. 2015, 5(1), 82-95.
| Keywords: | beta-TGdR, 6-Thio-dG |
| Application: | Nucleoside analog, telomeric DNA damage inducer |
| CAS | 789-61-7 |
| MW: | 283.31 D |
From 51.00€
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Telomerase reverse transcriptase (TERT), partial, human,...
Item number: CSB-EP023391HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 281-436aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: EATSLEGALS GTRHSHPSVG RQHHAGPPST SRPPRPWDTP CPPVYAETKH FLYSSGDKEQ LRPSFLLSSL RPSLTGARRL VETIFLGSRP WMPGTPRRLP RLPQRYWQMR PLFLELLGNH AQCPYGVLLK THCPLRAAVT...
| Keywords: | TP2, EST2, TERT, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, Telomerase reverse transcriptase,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 22.7 kD |
From 244.00€
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Telomerase reverse transcriptase (Tert), partial, mouse,...
Item number: CSB-EP023391MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 595-928aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: EVRHHQDTWL AMPICRLRFI PKPNGLRPIV NMSYSMGTRA LGRRKQAQHF TQRLKTLFSM LNYERTKHPH LMGSSVLGMN DIYRTWRAFV LRVRALDQTP RMYFVKADVT GAYDAIPQGK LVEVVANMIR...
| Keywords: | Tert, EC=2.7.7.49, Telomerase catalytic subunit, Telomerase reverse transcriptase, Recombinant Mouse Telomerase reverse... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 54.1 kD |
From 360.00€
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