57 products were found matching "K10684"!
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COH000
Item number: TGM-T5199-100mg
Description: COH000 is a covalent and irreversible inhibitor of small ubiquitin-like modifier (SUMO)-activating enzyme and inhibited SUMOylation (IC50: ~ 0.2 µM in vitro). Target: E1/E2/E3 Enzyme. Smiles: [H][C@]12O[C@@](C=C1)([C@@H](Cc1ccc(C)cc1)Nc1ccccc1)C(C(=O)OC)=C2C(=O)OC. References: Li YJ, et al. Allosteric...
| Application: | SUMO-activating enzyme inhibitor |
| CAS | 1534358-79-6 |
| MW: | 419.47 D |
From 228.00€
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Ginkgolic Acid
Item number: TGM-T6S2123-1mL
Description: Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC. Target: Others, E1/E2/E3 Enzyme. Smiles: CCCCCC\C=C/CCCCCCCc1cccc(O)c1C(O)=O. References: Hua Z , Wu C , Fan G , et al. The antibacterial activity and mechanism of ginkgolic acid C15:1[J]. BMC Biotechnology,...
| Keywords: | Romanicardic acid, Ginkgolic acid C15:1, Ginkgolic acid (15:1), Ginkgolic acid I |
| Application: | SUMOylation inhibitor |
| CAS | 22910-60-7 |
| MW: | 346.5 D |
From 60.00€
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SAE1 Protein, Human, Recombinant (His & GST)
Item number: TGM-TMPY-03062-100ug
Description: SAE1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 66.3 kDa and the accession number is Q9UBE0.
| Keywords: | UBLE1A, SUMO1 activating enzyme subunit 1, AOS1, SUA1, HSPC140 |
| MW: | 66.3 kD |
599.00€
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SAE1 Protein, Human, Recombinant
Item number: TGM-TMPY-03441-100ug
Description: SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
| Keywords: | HSPC140, AOS1, UBLE1A, SUA1, SUMO1 activating enzyme subunit 1 |
| MW: | 38.6 kD |
From 228.00€
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ML-792
Item number: TGM-T16102-100mg
Description: ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 µM and >100 µM, respectively), ML-792 is an effective and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50s of 3 and 11 nM,...
| Application: | SUMO-activating enzyme inhibitor |
| CAS | 1644342-14-2 |
| MW: | 551.41 D |
From 83.00€
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SUMO-activating enzyme subunit 1 (SAE1), human, recombinant
Item number: CSB-EP883359HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-346aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MVEKEEAGGG ISEEEAAQYD RQIRLWGLEA QKRLRASRVL LVGLKGLGAE IAKNLILAGV KGLTMLDHEQ VTPEDPGAQF LIRTGSVGRN RAEASLERAQ NLNPMVDVKV DTEDIEKKPE SFFTQFDAVC LTCCSRDVIV...
| Keywords: | AOS1, SAE1, Recombinant Human SUMO-activating enzyme subunit 1 (SAE1) |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 65.4 kD |
From 219.00€
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Anti-SAE1
Item number: CSB-PA004045.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-AOS1, Anti-SAE1, Activator of SUMO1 antibody, AOS1 antibody, HSPC140 antibody, Sae1 antibody, SAE1_HUMAN antibody,... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-SAE1
Item number: CSB-PA493084.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SAE1. Antigen Species: Human
| Keywords: | Anti-AOS1, Anti-SAE1, Activator of SUMO1 antibody, AOS1 antibody, HSPC140 antibody, Sae1 antibody, SAE1_HUMAN antibody,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-SAE1
Item number: CSB-PA794022.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-AOS1, Anti-SAE1, Activator of SUMO1 antibody, AOS1 antibody, HSPC140 antibody, Sae1 antibody, SAE1_HUMAN antibody,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
283.00€
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Anti-SAE1
Item number: CSB-PA897667.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SAE1. Antigen Species: Human
| Keywords: | Anti-AOS1, Anti-SAE1, Activator of SUMO1 antibody, AOS1 antibody, HSPC140 antibody, Sae1 antibody, SAE1_HUMAN antibody,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anacardic Acid monoene
Item number: Cay18422-1
Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts....
| Keywords: | Anacardic Acid 15:1, Ginkgolic Acid I, Ginkogolic Acid C15:1, 2-hydroxy-6-(8Z)-8-pentadecenyl-benzoic acid |
| Application: | SUMOylation inhibitor |
| CAS | 22910-60-7 |
| MW: | 346.5 D |
From 85.00€
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Anti-phospho-SUMO Activating Enzyme E1 (SAE1) (Ser185)
Item number: 600-401-B24
Protein function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. [The UniProt Consortium]
| Keywords: | Anti-phospho-AOS1, Anti-phospho-SAE1, Anti-phospho-SUMO-activating enzyme subunit 1, Anti-phospho-Ubiquitin-like... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 180.00€
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