- Search results for K10161
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55 products were found matching "K10161"!
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Item number: IAX-200-001-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
Application: | TLR9 activator |
MW: | 6383 D |
From 218.00€
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Item number: TGM-T4068-100mg
Description: E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs, potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM. Target: TLR. Smiles: Cl.Cl.C(COc1ccc(cc1)-c1nc2ccc(OCCCN3CCCC3)cc2o1)CN1CCCC1. References: Lamphier M, et al. Novel small molecule inhibitors of...
Application: | TLR7 / TLR9 antagonist |
CAS | 1345675-25-3 |
MW: | 522.51 D |
From 109.00€
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Item number: DIM-FLP100146.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Keywords: | TLR9, CD289, Toll-like receptor 9, CD289, Human TLR9 full length protein-synthetic nanodisc |
Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Expressed in: | Human cells |
Origin: | human |
MW: | 115.9 kD |
From 1,291.00€
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Item number: IAX-200-004-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Keywords: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
Application: | TLR9 activator |
MW: | 6644 D |
From 218.00€
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Item number: IAX-200-052-M001
Potent sequence of an inhibitory ODN of the poly-G class I targeting TLR9, but without effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Keywords: | Inhibitory ODN (iODN): Class I |
Application: | TLR9 competitor |
MW: | 6735 D |
From 179.00€
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Item number: IAX-200-002-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
Application: | TLR9 activator |
Species reactivity: | mouse, rat |
MW: | 6383 D |
From 218.00€
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Item number: IAX-200-006-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
Keywords: | CpG ODN TLR9 Agonist: B Type (species: human and rodent) |
Application: | TLR9 activator |
MW: | 7720 D |
From 218.00€
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Item number: IAX-200-005-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Keywords: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
Application: | TLR9 activator |
MW: | 6644 D |
From 218.00€
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Item number: Cay13593-1
The toll-like receptors (TLRs) in mammals comprise a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Like their counterparts in Drosophila, TLRs signal through adaptor...
Keywords: | TLR9 |
Application: | WB, FC (intracellular, Cell surface), IHC (frozen/paraffin), ICC |
Host: | Mouse |
Species reactivity: | human |
464.00€
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Item number: IAX-200-003-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2218 (Cat. No.: IAX-200-203). Unmethylated CG dinucleotides within particular sequence contexts are...
Keywords: | CpG ODN TLR9 Agonist: A Type (species: rodent) |
Application: | TLR9 activator |
MW: | 6643 D |
From 218.00€
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Item number: IAX-200-050-3001
3 x 1 mg. Potent sequence of an inhibitory ODN for in vivo use in rodents (50-150 µg per injection): prototype class I, may also affect TLR7 and TLR8 signaling. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Keywords: | Inhibitory ODN (iODN): Class I |
Application: | TLR9 competitor |
MW: | 4887 D |
From 179.00€
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Item number: IAX-200-007-C100
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Keywords: | CpG ODN: C Type (species: human and rodent) |
Application: | TLR9 activator |
MW: | 7068 D |
From 218.00€
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