190 products were found matching "K10160"!
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Mosedipimod
Item number: TGM-T28087-100mg
Description: Mosedipimod is an immunomodulator. Target: Others. Smiles: C(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COC(CCCCCCCCCC CCCCC)=O)COC(C)=O
| Application: | Targets toll-like receptor 4 (TLR4, CD284) |
| CAS | 221139-79-3 |
| MW: | 634.97 D |
From 1,491.00€
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T-5342126
Item number: TGM-T35864-10mg
Description: T-5342126 is a toll-like receptor 4 (TLR4) antagonist that reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50 = 27.8 µM) and decreases LPS-induced IL-8, TNF-alpha, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 µM, respectively). T-5342126...
| Application: | TLR4 antagonist |
| CAS | 956507-49-6 |
| MW: | 457.99 D |
From 140.00€
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Eritoran Tetrasodium
Item number: TGM-T27281-5mg
Description: Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes. Target: Others. Smiles: [Na].CCCCCCCCCC...
| Keywords: | E 5564, B 1287, B-1287, E5564, E-5564, B1287 |
| Application: | Targets toll-like receptor 4 (TLR4, CD284) |
| CAS | 185954-98-7 |
| MW: | 1336.666 D |
Please request pricing for this article.
CAY10614
Item number: TGM-T38366-10mg
Description: CAY10614 is a TLR4 antagonist. CAY10614 inhibits lipid A-induced activation of TLR4 (IC50=1.675 µM). CAY10614 also improves survival in LPS-induced shock model mice. Target: Others. Smiles: [I-].CCCCCCCCCC CCCCOc1ccc(C[N+](C)(C)C2CCCC2)cc1OCCCCCCCCCCCCCC
| Keywords: | CAY10614 |
| Application: | TLR4 antagonist |
| CAS | 1202208-36-3 |
| MW: | 755.995 D |
From 135.00€
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(R)-3-hydroxy Myristic Acid
Item number: TGM-T38041-100mg
Description: (R)-3-hydroxy Myristic Acid is an antifungal compound from Lactobacillus plantarum MiLAB 14 with antioxidant, anti-elastase, and anti-urease activities and can be used in the study of fungal infections. Target: Antifungal, Serine Protease, Antioxidant. Smiles: C(CCCCCCCCCC)[C@H](CC(O)=O)O. References:...
| Application: | Lipid A component |
| CAS | 28715-21-1 |
| MW: | 244.37 D |
From 70.00€
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L6H21
Item number: TGM-T69626-10mg
Description: L6H21 is an inhibitor of the interaction and signaling transduction of LPS-TLR4/MD-2 (myeloid differentiation 2). Target: Others. Smiles: O(C)C1=C(/C=C/C(=O)C2=CC=C(OC)C=C2)C=CC=C1OC
| Application: | MD-2 - TLR4 interaction inhibitor |
| CAS | 24533-47-9 |
| MW: | 298.33 D |
From 77.00€
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MD2-TLR4-IN-1
Item number: TGM-T7672-100mg
Description: MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor. Target: TLR. Smiles: Clc1cccc(Cl)c1C(=O)Nc1ccc2[nH]nc(-c3ccc4[nH]ccc4c3)c2c1. References: Zhiguo, Liu, Lingfeng, et al. Discovery of 3-(Indol-5-yl)-indazole Derivatives as Novel Myeloid...
| Application: | TLR4 antagonist |
| CAS | 2249801-12-3 |
| MW: | 421.28 D |
From 91.00€
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NCI 126224
Item number: TGM-T83895-10mg
Description: NCI 126224, a toll-like receptor 4 (TLR4) antagonist, demonstrates selective inhibition of nitric oxide (NO) production in RAW 264.7 macrophages, triggered by the TLR4 agonist LPS (IC50 = 0.31 µM), as opposed to minimal effects on NO production induced by agonists for TLR7/8 (R-848), TLR1/2 (Pam3CSK4),...
| Keywords: | NSC 126224 |
| Application: | TLR4 antagonist |
| CAS | 65974-52-9 |
| MW: | 265.2 D |
From 86.00€
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TLR4-IN-C34
Item number: TGM-T8503-100mg
Description: TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. Target: TLR. Smiles: CC(C)O[C@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1NC(C)=O. References: Neal MD, et al. Discovery and validation of a new class of small...
| Application: | TLR4 signaling inhibitor |
| CAS | 40592-88-9 |
| MW: | 389.4 D |
From 38.00€
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TLR4 Protein, Human, Recombinant (His)
Item number: TGM-TMPY-02904-100ug
Description: TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize...
| Keywords: | TLR-4, TOLL, TLR4, ARMD10, CD284, toll-like receptor 4 |
| MW: | 70.5 kD |
From 378.00€
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Resatorvid
Item number: TGM-TQ0181-100mg
Description: Resatorvid (TAK-242), a selective Toll-like receptor 4 (TLR4) inhibitor, binds directly to Cys747 to prevent TLR4-TIRAP interaction, thereby blocking downstream signaling. Resatorvid exhibits antitumor, anti-inflammatory, and neuroprotective activities. Target: Autophagy, TLR, Interleukin, TNF....
| Keywords: | TAK-242, CLI-095 |
| Application: | TLR4 adaptor binding inhibitor |
| CAS | 243984-11-4 |
| MW: | 361.82 D |
From 45.00€
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Mifamurtide sodium hydrate
Item number: TGM-TP2332-100mg
Description: Mifamurtide protects mice against herpes simplex virus type 2. It also is a macrophage activator. Smiles: O.[Na+].CCCCCCCCCC CCCCCC(=O)OCC(COP([O-])(=O)OCCN(C(C)C(=O)NC(=O)C(CCC(N)=O)NC(=O)C(C)N)C(=O)C(C)OC1C(O)C(CO)OC(O)C1NC(C)=O)OC(=O)CCCCCCCCCCCCCCC. References: Signorell RD, Luciani P, Brambilla D,...
| Keywords: | L-MTP-PE, Mifamurtide, Muramyl tripeptide |
| Application: | Targets toll-like receptor 4 (TLR4, CD284) |
| CAS | 838853-48-8 |
| MW: | 1277.515 D |
Please request pricing for this article.