167 products were found matching "K10160"!
No results were found for the filter!
NEW
Anti-TLR4, recombinant clone 2E10
Item number: CSB-RA023603MA1HU.100
Protein function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:27022195). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9237759, PubMed:10835634, PubMed:27022195). Also...
| Keywords: | Anti-TLR4, Anti-CD284, Anti-hToll, Anti-Toll-like receptor 4, TLR4 Recombinant Monoclonal Antibody |
| Application: | ELISA, FC |
| Host: | Human |
| Species reactivity: | human |
From 186.00€
*
NCI 126224
Item number: TGM-T83895-10mg
Description: NCI 126224, a toll-like receptor 4 (TLR4) antagonist, demonstrates selective inhibition of nitric oxide (NO) production in RAW 264.7 macrophages, triggered by the TLR4 agonist LPS (IC50 = 0.31 µM), as opposed to minimal effects on NO production induced by agonists for TLR7/8 (R-848), TLR1/2 (Pam3CSK4),...
| Keywords: | NSC 126224 |
| Application: | TLR4 antagonist |
| CAS | 65974-52-9 |
| MW: | 265.2 D |
From 88.00€
*
TLR4-IN-C34
Item number: TGM-T8503-100mg
Description: TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. Target: TLR. Smiles: CC(C)O[C@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1NC(C)=O. References: Neal MD, et al. Discovery and validation of a new class of small...
| Application: | TLR4 signaling inhibitor |
| CAS | 40592-88-9 |
| MW: | 389.4 D |
From 40.00€
*
TLR4 Protein, Human, Recombinant (His)
Item number: TGM-TMPY-02904-100ug
Description: TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize...
| Keywords: | TLR-4, TOLL, TLR4, ARMD10, CD284, toll-like receptor 4 |
| MW: | 70.5 kD |
From 385.00€
*
Resatorvid
Item number: TGM-TQ0181-100mg
Description: Resatorvid (TAK-242), a selective Toll-like receptor 4 (TLR4) inhibitor, binds directly to Cys747 to prevent TLR4-TIRAP interaction, thereby blocking downstream signaling. Resatorvid exhibits antitumor, anti-inflammatory, and neuroprotective activities. Target: Autophagy, TLR, Interleukin, TNF....
| Keywords: | TAK-242, CLI-095 |
| Application: | TLR4 adaptor binding inhibitor |
| CAS | 243984-11-4 |
| MW: | 361.82 D |
From 45.00€
*
Mifamurtide sodium hydrate
Item number: TGM-TP2332-100mg
Description: Mifamurtide protects mice against herpes simplex virus type 2. It also is a macrophage activator. Smiles: O.[Na+].CCCCCCCCCC CCCCCC(=O)OCC(COP([O-])(=O)OCCN(C(C)C(=O)NC(=O)C(CCC(N)=O)NC(=O)C(C)N)C(=O)C(C)OC1C(O)C(CO)OC(O)C1NC(C)=O)OC(=O)CCCCCCCCCCCCCCC. References: Signorell RD, Luciani P, Brambilla D,...
| Keywords: | L-MTP-PE, Mifamurtide, Muramyl tripeptide |
| Application: | Targets toll-like receptor 4 (TLR4, CD284) |
| CAS | 838853-48-8 |
| MW: | 1277.515 D |
Please request pricing for this article.
VGX-1027
Item number: TGM-T1813-100mg
Description: VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties. Target: TNF, Interleukin, IL Receptor. Smiles: OC(=O)CC1CC(=NO1)c1ccccc1. References: Stosic-Grujicic S, et al. J Pharmacol Exp Ther. 2007, 320(3), 1038-1049.
| Keywords: | VGX1027, VGX 1027, GIT 27 |
| Application: | Immunomodulatory agent |
| CAS | 6501-72-0 |
| MW: | 205.21 D |
From 42.00€
*
(R)-3-hydroxy Myristic Acid
Item number: TGM-T38041-100mg
Description: (R)-3-hydroxy Myristic Acid is an antifungal compound from Lactobacillus plantarum MiLAB 14 with antioxidant, anti-elastase, and anti-urease activities and can be used in the study of fungal infections. Target: Antifungal, Serine Protease, Antioxidant. Smiles: C(CCCCCCCCCC)[C@H](CC(O)=O)O. References:...
| Application: | Lipid A component |
| CAS | 28715-21-1 |
| MW: | 244.37 D |
From 71.00€
*
Anti-TLR4 (Capture/Detector)
Item number: E-AN000790P.1
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three...
| Keywords: | Anti-TLR4, Anti-CD284, Anti-hToll, Anti-Toll-like receptor 4, TLR4 Polyclonal Antibody(Capture/Detector) |
| Application: | ELISA Capture/Detector |
| Host: | Rabbit |
| Species reactivity: | human |
From 158.00€
*
TLR4 Protein (Fc Tag) (recombinant rat)
Item number: E-PDMR100059.100
Sequence: Asn26-Lys629. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 110-120 kDa. Protein function: TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and...
| Keywords: | Tlr4, CD284, Toll4, Toll-like receptor 4, Recombinant Rat TLR4 Protein(Fc Tag) |
| Expressed in: | Mammalian |
| Origin: | rat |
From 304.00€
*
Mosedipimod
Item number: TGM-T28087-100mg
Description: Mosedipimod is an immunomodulator. Target: Others. Smiles: C(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COC(CCCCCCCCCC CCCCC)=O)COC(C)=O
| Application: | Targets toll-like receptor 4 (TLR4, CD284) |
| CAS | 221139-79-3 |
| MW: | 634.97 D |
From 1,520.00€
*
T-5342126
Item number: TGM-T35864-10mg
Description: T-5342126 is a toll-like receptor 4 (TLR4) antagonist that reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50 = 27.8 µM) and decreases LPS-induced IL-8, TNF-alpha, and IL-6 production in isolated human whole blood (IC50s = 110.5, 315.6, and 318.4 µM, respectively). T-5342126...
| Application: | TLR4 antagonist |
| CAS | 956507-49-6 |
| MW: | 457.99 D |
From 142.00€
*