- Search results for K09093
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108 products were found matching "K09093"!
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Item number: CSB-EP001481HU3.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 220-420aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: FICRLRCLLD NSSGFLAMNF QGKLKYLHGQ KKKGKDGSIL PPQLALFAIA TPLQPPSILE IRTKNFIFRT KHKLDFTPIG CDAKGRIVLG YTEAELCTRG SGYQFIHAAD MLYCAESHIR MIKTGESGMI VFRLLTKNNR...
Keywords: | AhR, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76, Recombinant Human Aryl... |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 29.0 kD |
From 283.00€
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Item number: Cay36939-10
BAY-2416964 is an antagonist of the aryl hydrocarbon receptor (AhR, IC50 = 22 nM in U87 cells). It decreases the mRNA expression of the AhR target genes CYP1A1 and AHRR induced by the AhR agonist kynurenic acid (Cay-16792) in LPS-stimulated isolated human monocytes when used at a concentration of 100 nM. BAY-2416964...
Keywords: | 6-(4-chlorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-4-pyridazinecarboxamide |
Application: | AhR antagonist |
CAS | 2242464-44-2 |
MW: | 387.8 D |
From 80.00€
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Item number: ELK-ELK1891.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AhR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AhR. Next,...
Keywords: | AhR, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: IB-IB06001
INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Keywords: | Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E... |
Application: | Functional activity screening |
From 1,448.00€
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Item number: Cay11305-50
L-Kynurenine is an active metabolite of tryptophan (Cay-29600, Cay-31210). It is formed from tryptophan via tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO). L-Kynurenine binds to the aryl hydrocarbon receptor (AhR, Kd = ~4 µM) and increases the activity of ethoxyresorufin-O-deethylase (EROD) in...
Keywords: | 3-anthraniloyl-Alanine, alphaS,2-diamino-gamma-oxo-benzenebutanoic acid |
Application: | AHR ligand |
CAS | 2922-83-0 |
MW: | 208.2 D |
From 50.00€
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Item number: Cay10625-1
Extending the pluripotency of hematopoietic stem cells (HSC) is of key importance to the application of stem cell therapies in a variety of diseases. Loss of the expression of the cell surface proteins CD34 and CD133 is one marker of HSC differentiation and thus often monitored in assays to test potential compounds...
Keywords: | SR1, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol |
Application: | Aryl hydrocarbon receptor inhibitor |
CAS | 1227633-49-9 |
MW: | 429.5 D |
From 39.00€
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Item number: Cay16924-1
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. alpha-Naphthoflavone is a flavone that modulates xenobiotic metabolism at...
Keywords: | 7,8-Benzoflavone, NSC 407011, 2-phenyl-4H-naphtho[1,2-b]pyran-4-one |
Application: | AhR expression modulator |
CAS | 604-59-1 |
MW: | 272.3 D |
From 39.00€
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Item number: Cay36307-1
L-Kynurenine-d4 is intended for use as an internal standard for the quantification of kynurenine by GC- or LC-MS. L-Kynurenine is an active metabolite of tryptophan (Cay-29600, Cay-31210). It is formed from tryptophan via tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO). L-Kynurenine binds to...
Keywords: | 3-anthraniloyl-Alanine-d4, L-KYN-d4, (S)-2-amino-4-(2-aminophenyl-3,5-d2)-4-oxobutanoic-3,3-d2 acid |
Application: | GC-MS, LC-MS internal standard, quantification, AHR ligand |
CAS | 2672568-86-2 |
MW: | 212.2 D |
From 75.00€
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Item number: Cay16476-1
Biochanin A is a natural isoflavone with diverse biological actions, most notably as a phytoestrogen. It can affect hormone levels by inhibiting 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase or altering aromatase (CYP19A1) activity. Also known as 4'-methyl genistein, biochanin A can be metabolized in vivo...
Keywords: | 4'-methyl Genistein, 5,7-dihydroxy-4'-Methoxyisoflavone, NSC 123538, 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Application: | Phytoestrogen, AHR agonist |
CAS | 491-80-5 |
MW: | 284.3 D |
From 48.00€
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Item number: Cay17558-5
Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein (Cay-10005166). It acts as an agonist of the aryl hydrocarbon receptor with an EC50 value of 0.13 µM. Formononetin has been reported to possess antitumor and antiviral activity.Formal Name:...
Keywords: | Biochanin B, NSC 93360, 7-hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Application: | Aryl hydrocarbon receptor agonist |
CAS | 485-72-3 |
MW: | 268.3 D |
From 43.00€
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Item number: Cay16154-5
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that up-regulates many xenobiotic metabolizing enzymes, particularly in response to planar aromatic hydrocarbons. CH 223191 is a potent and specific antagonist of AhR that blocks activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD,...
Keywords: | 1-methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide |
Application: | Aryl hydrocarbon receptor (AhR) antagonist |
CAS | 301326-22-7 |
MW: | 333.4 D |
From 81.00€
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Item number: Cay19529-1
6-Formylindolo[3,2-b]carbazole (FICZ) is a degradation product of tryptophan upon exposure to visible light that activates the aryl hydrocarbon receptor (AhR, Kd = 70 pM). This endogenous AhR ligand is also a good substrate for cytochromes P450 (CYP) 1A1, 1A2, and 1B1 (Kis = 15.4, 3.9, and 13.3 µM, respectively)....
Keywords: | FICZ, 5,11-dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde |
Application: | AhR agonist |
CAS | 172922-91-7 |
MW: | 284.3 D |
From 84.00€
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