131 products were found matching "K09093"!
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3-Methylindole
Item number: Cay39231-10
An endogenous tryptophan metabolite and fecal odorant, induces AhR transactivation in a reporter assay using Caco-2 cells at 1 mM, induces p38 MAPK activation and apoptosis in Caco-2 cells at 1 mM, intraruminal administration induces respiratory distress in sheep at 0. g/kg, has been found in cigarette smokeInChI:...
| Keywords: | NSC 122024, Skatole, 3-methyl-1H-indole |
| Application: | Endogenous tryptophan metabolite, fecal odorant, AhR activator |
| CAS | 83-34-1 |
| MW: | 131.2 D |
From 40.00€
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BAY-218
Item number: TGM-T5622-100mg
Description: BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist with an IC50 of 39.9 nM in a human cell line. Target: Aryl Hydrocarbon Receptor, AhR. Smiles: C[C@@H](CO)NC(=O)c1cc(nn(-c2cccc(F)c2)c1=O)-c1ccc(Cl)cc1. References: Ilona Gutcher, Christina Kober, Lars Roese,et al.Abstract 1288:...
| Keywords: | AHR antagonist 1 |
| Application: | AhR antagonist |
| CAS | 2162982-11-6 |
| MW: | 401.82 D |
From 34.00€
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Indoxyl Sulfate-d5 potassium salt
Item number: TGM-T70313-100mg
Description: Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of indole, an intermediate generated from tryptophan by intestinal bacteria, by the...
| Application: | GC-MS, LC-MS internal standard, quantification |
| CAS | 1644451-34-2 |
| MW: | 256.3278 D |
From 1,520.00€
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ITE
Item number: TGM-T7202-100mg
Description: ITE is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) (Ki: 3 nM) with immunosuppressive activity. Target: AhR, Aryl Hydrocarbon Receptor. Smiles: COC(=O)c1csc(n1)C(=O)c1c[nH]c2ccccc12. References: Pang L P , Li Y , Zou Q Y , et al. ITE inhibits growth of human pulmonary artery...
| Application: | Endogenous AhR agonist |
| CAS | 448906-42-1 |
| MW: | 286.31 D |
From 34.00€
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SGA360
Item number: TGM-T8980-100mg
Description: SGA360 is a selective aryl hydrocarbon (Ah) receptor modulator. It exhibits anti-inflammatory properties. Target: Aryl Hydrocarbon Receptor. Smiles: C(C=C)N1C=2C(C(=N1)C3=C(OC)C=C(OC)C=C3)=CC=CC2C(F)(F)F. References: Muku G E , Lahoti T S , Murray I A , et al. Ligand-mediated cytoplasmic retention of...
| Application: | AHR modulator |
| CAS | 680611-86-3 |
| MW: | 362.35 D |
From 40.00€
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5-methyl Chrysene
Item number: TGM-T84400-10mg
Description: 5-Methylchrysene, a carcinogenic polycyclic aromatic hydrocarbon with four fused rings, functions as an aryl hydrocarbon receptor agonist. It is generated through the incomplete combustion of organic matter and primarily detected in gasoline exhaust and tobacco smoke. Additionally, 5-Methylchrysene can...
| Keywords: | NSC 407620 |
| Application: | AH receptor agonist |
| CAS | 3697-24-3 |
| MW: | 242.3 D |
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CAY10464
Item number: TGM-T84540-10mg
Description: CAY10464 (AHR antagonist 7) is a potent AHR antagonist with potential antitumor activity that inhibits CYP1A1 mRNA expression and may be used to study cancer and metabolic diseases. Target: AhR. Smiles: C(=C/C1=CC(Cl)=CC(Cl)=C1)\C2=CC=C(OC)C=C2
| Keywords: | AHR antagonist 7 |
| Application: | AhR antagonist |
| CAS | 688348-37-0 |
| MW: | 279.16 D |
From 42.00€
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AHR Protein, Human, Recombinant (His)
Item number: TGM-TMPH-00958-100ug
Description: AHR Protein, Human, Recombinant (His) is expressed in E. coli.
| Keywords: | Class E basic helix-loop-helix protein 76, Aryl hydrocarbon receptor, bHLHe76, Ah receptor |
| MW: | 29.0 kD |
From 281.00€
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L-Kynurenine-d4
Item number: TGM-TMID-0071-1mg
Description: L-Kynurenine-d4 is a deuterated compound of L-Kynurenine. L-Kynurenine has a CAS number of 2922-83-0. L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has...
| Application: | GC-MS, LC-MS internal standard, quantification, AHR ligand |
| CAS | 2672568-86-2 |
| MW: | 212.24 D |
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FICZ
Item number: TGM-TQ0257-1mg
Description: FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM). Target: Aryl Hydrocarbon Receptor. Smiles: O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12. References: Mohammadi-Bardbori A, et al. The highly bioactive molecule and signal substance...
| Keywords: | 6-Formylindolo[3,2-b]carbazole |
| Application: | AhR agonist |
| CAS | 172922-91-7 |
| MW: | 284.31 D |
From 46.00€
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StemRegenin 1
Item number: TGM-T1831-100mg
Description: StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor. Target: AhR, Aryl Hydrocarbon Receptor. Smiles: CC(C)n1cnc2c(NCCc3ccc(O)cc3)nc(nc12)-c1csc2ccccc12. References: Boitano AE, et al. Science, 2010, 329(5997), 1345-1348.
| Keywords: | SR1 |
| Application: | Aryl hydrocarbon receptor inhibitor |
| CAS | 1227633-49-9 |
| MW: | 429.54 D |
From 33.00€
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VAF347
Item number: TGM-T13276-100mg
Description: VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. Target: Aryl Hydrocarbon Receptor. Smiles: FC(F)(F)c1ccc(Nc2nccc(n2)-c2cccc(Cl)c2)cc1. References: Ibabao CN, et al. The AhR agonist VAF347 augments retinoic acid-induced...
| Application: | AhR agonist |
| CAS | 574759-62-9 |
| MW: | 349.74 D |
From 34.00€
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