54 products were found matching "K08865"!
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Anti-PBK
Item number: ABS-KC-3911.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage. [The UniProt...
| Keywords: | Anti-Lymphokine-activated killer T-cell-originated protein kinase, Anti-Cancer/testis antigen 84, Anti-CT84,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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HUMAN PBK Peptide Pool
Item number: PE-LB01750.1
Pool of 78 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Lymphokine-activated killer T-cell-originated protein kinase (UniProtKB - Q96KB5) for T cell assays. One unit allows the stimulation of 2,5 x 10^8 cells.You can find applications and references in our blog post:...
| Keywords: | PBK, SPK, TOPK, CT84, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
| Origin: | human |
312.00€
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OTS514
Item number: TGM-T4134L-10mg
Description: OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment...
| Keywords: | OTS514 Hydrochloride, OTS514 HCl, OTS-514, OTS 514 |
| Application: | TOPK inhibitor |
| CAS | 1338540-63-8 |
| MW: | 364.46 D |
From 88.00€
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OTS964 hydrochloride
Item number: TGM-T4135-100mg
Description: OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity. Target: CDK, Apoptosis, TOPK. Smiles: Cl.C[C@@H](CN(C)C)c1ccc(cc1)-c1c(O)cc(C)c2[nH]c(=O)c3sccc3c12. References: Matsuo Y, et al. TOPK inhibitor induces complete tumor regression in xenograft...
| Keywords: | OTS964 |
| Application: | PBK / TOPK inhibitor |
| CAS | 1338545-07-5 |
| MW: | 428.97 D |
From 40.00€
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PBK/TOPK Protein, Human, Recombinant (His)
Item number: TGM-TMPY-04547-50ug
Description: PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is...
| Keywords: | PDZ binding kinase, SPK, CT84, Nori-3, HEL164, TOPK |
| MW: | 37 kD |
599.00€
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HI-TOPK-032
Item number: TGM-T15481-100mg
Description: HI-TOPK-032 is an effective and specific inhibitor of TOPK. Target: TOPK. Smiles: O=C(Nc1ccn2c(c1)c(C#N)c1nc3ccccc3nc21)c1cccs1. References: Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15,72(12):3060-8.
| Application: | PBK inhibitor |
| CAS | 487020-03-1 |
| MW: | 369.4 D |
From 40.00€
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Lymphokine-activated killer T-cell-originated protein...
Item number: CSB-EP822241HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-322aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MEGISNFKTP SKLSEKKKSV LCSTPTINIP ASPFMQKLGF GTGVNVYLMK RSPRGLSHSP WAVKKINPIC NDHYRSVYQK RLMDEAKILK SLHHPNIVGY RAFTEANDGS LCLAMEYGGE KSLNDLIEER YKASQDPFPA...
| Keywords: | PBK, SPK, CT84, TOPK, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 63.1 kD |
From 219.00€
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Lymphokine-activated killer T-cell-originated protein...
Item number: CSB-EP822241HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-322aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MEGISNFKTP SKLSEKKKSV LCSTPTINIP ASPFMQKLGF GTGVNVYLMK RSPRGLSHSP WAVKKINPIC NDHYRSVYQK RLMDEAKILK SLHHPNIVGY RAFTEANDGS LCLAMEYGGE KSLNDLIEER...
| Keywords: | PBK, SPK, CT84, TOPK, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 42.1 kD |
From 219.00€
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Anti-Phospho-PBK (T9)
Item number: CSB-PA030267.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-phospho-SPK, Anti-phospho-PBK, Anti-phospho-CT84, Anti-phospho-TOPK, Anti-phospho-Nori-3, EC=2.7.12.2,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-PBK
Item number: CSB-PA030268.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-SPK, Anti-PBK, Anti-CT84, Anti-TOPK, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, monkey |
From 126.00€
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OTS964 (hydrochloride)
Item number: Cay17052-5
OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK, IC50 = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.Formal Name:...
| Keywords: | 9-[4-[(1R)-2-(dimethylamino)-1-methylethyl]phenyl]-8-hydroxy-6-methyl-thieno[2,3-c]quinolin-4(5H)-one, monohydrochloride |
| Application: | PBK / TOPK inhibitor |
| CAS | 1338545-07-5 |
| MW: | 429 D |
From 67.00€
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OTS-964
Item number: LKT-O783720.25
inhibitor of T-lymphokine-activated killer cell-originated protein kinase (TOPK).
| Application: | TOPK inhibitor |
| CAS | 1338545-07-5 |
| MW: | 378.49 D |
From 189.00€
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