18 products were found matching "K08863"!
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PLK4, GST-tag
Item number: BPS-40236
Human polo-like kinase 4 (PLK4), also known as serine/threonine protein kinase 18 (STK18), SAK, GenBank Accession No. NM_014264, a.a. 1-836 with an N-terminal GST-tag, expressed in a baculovirus-infected Sf9 cell expression system. MW = 140 kDa.
| Keywords: | SAK, PLK-4, Polo-like kinase 4, Serine/threonine-protein kinase 18, Serine/threonine-protein kinase Sak,... |
| Application: | Studying enzyme kinetics, small molecule inhibitor screening |
| Expressed in: | insect cells |
| Origin: | human |
| MW: | 140 kD |
862.00€
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Centrinone
Item number: Cay24684-1
Centrinone is an inhibitor of polo-like kinase 4 (Plk4, Ki = 0.16 nM). It is greater than 1,100- and 2,800-fold selective for Plk4 over Aurora A and Aurora B kinases, respectively, and a panel of 442 kinases at 100 nM. Centrinone (125 nM) depletes centrosomes and induces apoptosis in HeLa cells.Formal Name:...
| Keywords: | LCR-263,... |
| Application: | Plk4 inhibitor |
| CAS | 1798871-30-3 |
| MW: | 633.6 D |
From 44.00€
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Anti-Sak / STK18 / PLK4, N-terminal
Item number: ARG63489.100
Protein function: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, EC=2.7.11.21, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | ELISA, WB |
| Host: | Goat |
| Species reactivity: | human |
736.00€
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CFI-400437
Item number: SYN-1207-M001
CFI-400437 is a potent PLK4 inhibitor (IC50=0.6nM) and selective against other members of the PLK family (>10µM). Against a broad panel of kinases, only a small subset is significantly inhibited. CFI-400437 is a potent inhibitor of MCF-7, MDA-MB-468 and MDA-MB-231 cell growth and very effective in a mouse xenograft...
| Keywords: | (E)-5-Methoxy-3-((3-((E)-2-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one... |
| Application: | Potent PLK4 inhibitor |
| MW: | 565.5 D |
From 250.00€
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Anti-PLK4
Item number: ARG40139.100
Protein function: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
624.00€
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Anti-PLK4
Item number: E-AB-18272.120
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 71.00€
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Anti-PLK4
Item number: ATA-HPA017327.100
Protein function: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 335.00€
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Anti-PLK4
Item number: ATA-HPA043198.100
Protein function: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 335.00€
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Anti-PLK4
Item number: ATA-HPA035026.100
Protein function: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When...
| Keywords: | Anti-SAK, Anti-PLK4, Anti-PLK-4, Anti-Polo-like kinase 4, Anti-Serine/threonine-protein kinase 18,... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 335.00€
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PhosphoSens Kinase Sensor Peptide
Item number: AQT-CSKS-AQT0898B
Bulk Sensor Peptide Substrate recommended for PLK4 PhosphoSens-Kinetic assays and PLK4 PhosphoSens-Red assays
| Keywords: | PLK4 |
3,744.00€
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PhosphoSens Kinase Sensor Peptide
Item number: AQT-CSKS-AQT0898K
PhosphoSens Kinase Assay Kit recommended for PLK4 PhosphoSens-Kinetic assays
| Keywords: | PLK4 |
837.00€
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PhosphoSens Kinase Sensor Peptide
Item number: AQT-CSKS-AQT0898KR
PhosphoSens Kinase Assay Kit recommended for PLK4 PhosphoSens-Red assays
| Keywords: | PLK4 |
837.00€
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