- Search results for K08726
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40 products were found matching "K08726"!
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Item number: CSB-EP007735HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-555aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT TRLMKGEITL SQWIPLMEEN CRKCSETAKV CLPKNFSIKE IFDKAISARK INRPMLQAAL MLRKKGFTTA ILTNTWLDDR...
Keywords: | CEH, SEH, Epoxide hydratase, Soluble epoxide hydrolase, Lipid-phosphate phosphatase, Cytosolic epoxide hydrolase 2,... |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 78.6 kD |
From 213.00€
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Item number: Cay10009134-10
EpETrE metabolites of arachidonic acid such as 11(12-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors...
Keywords: | 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid |
Application: | sEH inhibitor screening |
CAS | 1028430-42-3 |
MW: | 373.4 D |
From 46.00€
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Item number: Cay11120-1
Soluble epoxide hydrolase (sEH) converts epoxides to their corresponding diols. Inhibitors of sEH have anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. TPPU is a potent inhibitor of both human and mouse sEH (IC50 = 3.7 and 2.8 nM, respectively). The pharmacokinetics of this...
Keywords: | N-[1-(1-oxopropyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl)-urea |
Application: | sEH inhibitor |
CAS | 1222780-33-7 |
MW: | 359.3 D |
From 43.00€
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Item number: Cay10642-1
Soluble epoxide hydrolase (sEH) inhibitors have important therapeutic use by increasing the in vivo concentration of EETs and other fatty acid epoxides, resulting in anti-inflammatory, antihypertensive, neuroprotective, and cardioprotective effects. CAY10640 is a 1-aryl-3-(1-acylpiperidin-4-yl)urea analog that...
Keywords: | sEHi, Soluble Epoxide Hydrolase Inhibitor, N-[1-(cyclopropylcarbonyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea |
Application: | Soluble epoxide hydrolase (sEH) inhibitor |
CAS | 1208549-68-1 |
MW: | 371.4 D |
From 73.00€
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Item number: Cay10011669-50
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols. It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase...
Keywords: | CEH, CEH, Epoxide hydratase, Epoxide hydratase, Lipid-phosphate phosphatase, Lipid-phosphate phosphatase, Cytosolic... |
Application: | Enzyme activity |
MW: | 64 kD |
514.00€
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Item number: Cay10007923-5
Epoxyeicosatrienoic acid (EpETrE, EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy eicosatrienoic acids...
Keywords: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
Application: | sEH inhibitor |
CAS | 479413-68-8 |
MW: | 340.5 D |
From 64.00€
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Item number: Cay38938-25
(±)13,14-DiHDoTrE is an oxylipin and a racemic mixture of the (R)/(S) enantiomeric forms biosynthesized from the adrenic acid metabolite (±)13,14-EDT (Cay-38937) by soluble epoxide hydrolase (sEH).Formal Name: 13,14-dihydroxy-7Z,10Z,16Z-docosatrienoic acid. CAS Number: 944908-94-5. Synonyms: (±)13,14-DHDT,...
Keywords: | (±)13,14-DHDT, (±)13,14-Dihydroxydocosatrienoic Acid, 13,14-dihydroxy-7Z,10Z,16Z-docosatrienoic acid |
Application: | Oxylipin |
CAS | 944908-94-5 |
MW: | 366.5 D |
From 145.00€
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Item number: Cay10465-25
Docosahexaenoic acid (DHA, Cay-90310) is the most abundant omega-3 fatty acid in neural tissues, especially in the brain and retina. (±)7(8)-EpDPA is an epoxide derivative of DHA that is generated by the action of cytochrome P450 epoxygenases. It is naturally occurring in plasma and brain and spinal cord tissues and...
Keywords: | (±)7,8-EDP, (±)7,8-EpDPE, (±)7,8-epoxy Docosapentaenoic Acid, (±)7,8-epoxy DPA,... |
Application: | Soluble epoxide hydrolase substrate |
CAS | 895127-66-9 |
MW: | 344.5 D |
From 56.00€
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Item number: Cay10464-25
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid (DHA, Cay-90310) epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred...
Keywords: | (±)13,14-EDP, (±)13,14-EpDPE, (±)13,14-epoxy Docosapentaenoic Acid, (±)13,14-epoxy DPA,... |
Application: | Soluble epoxide hydrolase substrate |
CAS | 895127-64-7 |
MW: | 344.5 D |
From 56.00€
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Item number: Cay10471-25
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA, Cay-90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human...
Keywords: | (±)10,11-EDP, (±)10,11-EpDPE, (±)10,11-epoxy Docosapentaenoic Acid, (±)10,11-epoxy DPA,... |
Application: | Soluble epoxide hydrolase substrate |
CAS | 895127-65-8 |
MW: | 344.5 D |
From 56.00€
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Item number: Cay38934-25
(±)7(S),8(S)-DiHDoTrE is an oxylipin.Formal Name: 7S,8S-dihydroxy-10Z,13Z,16Z-docosatrienoic acid. Synonyms: (±)7(S),8(S)-DHDT. Molecular Formula: C22H38O4. Formula Weight: 366.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO: 10 mg/ml, Ethanol: 10 mg/ml. SMILES:...
Keywords: | (±)7,8-DHDT, (±)-Dihydroxydocosatrienoic Acid, 7,8-dihydroxy-10Z,13Z,16Z-docosatrienoic acid |
Application: | Oxylipin |
MW: | 366.5 D |
From 145.00€
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Item number: Cay600090-480
Mammalian soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold family of enzymes that catalyze the hydrolysis of exogenous and endogenous epoxides to vicinal diols. sEH is a homodimer consisting of two domains. The C-terminal domain is responsible for the epoxide hydrolase activity while the...
Keywords: | Cytosolic Epoxide Hydrolase (CEH), EPHX2, Epoxide Hydrolase 2, sEH |
Application: | Cell based assays |
Species reactivity: | human |
553.00€
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