204 products were found matching "K08556"!

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Progesterone is one of the central regulators of female reproduction. In breast development, progesterone is involved in the formation of lobular-alveolar structures and also affects differentiation in the breast by modulation of milk protein...

1 mg/ml in 1X PBS, BSA free, sodium azide free. Progesterone is one of the central regulators of female reproduction. In breast development, progesterone is involved in the formation of lobular-alveolar structures and also affects differentiation in the breast by modulation of milk protein synthesis. The cellular...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PGR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PGR. Next,...

Mifepristone is an antagonist of glucocorticoid, progesterone, and androgen receptors (Kis = 0.1, 0.64, and 0.65 nM, respectively). It is selective for these receptors over the mineralocorticoid receptor (MR), estrogen receptor alpha (ERalpha), and ERbeta (Kis = 640, >200, and >750 nM, respectively). In cell-based...

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Delta4,5-isomerase in the outer mitochondrial membrane and smooth...

A progesterone receptor antagonist. It is an effective late post-coital contraceptive. Active against ovarian cancer, and induces apoptosis through modulation of HPV E6/E7 in dexamethasone treated cervical cacinoma cells.

Medroxyprogesterone 17-acetate is a synthetic progestogen.,, It prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation. Medroxyprogesterone 17-acetate reversibly blocks ovulation in rats when injected on the...

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...

Norethindrone is a synthetic progestin. In vivo, norethindrone (0.5 mg/animal per day) inhibits the estrous cycle in female mice. It induces tumor progression and metastasis in a BT474 breast cancer mouse xenograft model. Formulations containing norethindrone have been used as oral contraceptives.Formal Name:...

Danazol is a derivative of testosterone (Cay-15645) and ethisterone that can bind to androgen receptors and sex hormone-binding globulin causing a 3-fold increase in free testosterone. It possesses weak androgenic effects and inhibits the production of gonadotropins. It has been used to address symptoms of...

Drospirenone is a synthetic progestogen that binds to the progesterone, mineralocorticoid, and androgen receptors with binding affinities of 20, 230, and 65% relative to R5020, aldosterone (Cay-15273), and R1881, respectively. In vivo, drospirenone inhibits spontaneous ovulation in rats (ID50s = 0.3-1.0 mg/day) when...

Ulipristal acetate is a selective progesterone receptor modulator (SPRM) that binds to the human progesterone receptors PR-A and PR-B (EC50s = 8.5 and 7.7 nM, respectively), rabbit uterine PR (EC50 = 13.6 nM), and rabbit thymic glucocorticoid receptor (GR, EC50 = 15.4 nM). It is selective for human progesterone...