- Search results for K08531
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13 products were found matching "K08531"!
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Item number: TGM-T3685-10mg
Description: SR9009 (Stenabolic), a REV-ERB agonist, increases the constitutive repression of genes regulated by REV-ERBalpha/ERBbeta (IC50: 670/800 nM). Through activation of REV-ERB, SR9009 can decrease circadian locomotor activity during the dark phase and alter the expression pattern of core clock genes in the...
Keywords: | REV-ERB Agonist II, Stenabolic |
Application: | REV-ERB agonist |
CAS | 1379686-30-2 |
MW: | 437.94 D |
From 31.00€
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Item number: Cay11929-1
REV-ERBalpha and REV-ERBbeta nuclear receptors are transcriptional repressors that coordinate circadian rhythm and metabolic pathways in a heme-dependent manner. SR9009 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERBalpha and REV-ERBbeta with IC50 values of 670 and 800...
Keywords: | REV-ERB Agonist II, 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-1-pyrrolidinecarboxylic acid... |
Application: | REV-ERB agonist |
CAS | 1379686-30-2 |
MW: | 437.9 D |
From 35.00€
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Item number: Cay11930-5
SR9011 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERBalpha and REV-ERBbeta with IC50 values of 790 and 560 nM, respectively. It has no activity at other nuclear receptors. SR9011 blocks the activity of the suprachiasmatic nucleus (SCN) clock, with reversible inhibition...
Keywords: | 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide |
Application: | REV-ERB agonist |
CAS | 1379686-29-9 |
MW: | 479 D |
From 128.00€
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Item number: ARG57489.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | Anti-RVR, Anti-NR1D2, Anti-EAR-1R, Anti-Rev-erb-beta, Anti-Rev-erb alpha-related receptor, Anti-V-erbA-related protein... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
616.00€
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Item number: ATA-HPA053868.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | Anti-RVR, Anti-NR1D2, Anti-EAR-1R, Anti-Rev-erb-beta, Anti-Rev-erb alpha-related receptor, Anti-V-erbA-related protein... |
Application: | ICC, WB |
Host: | Rabbit |
Species reactivity: | human |
477.00€
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Item number: ATA-HPA054798.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | Anti-RVR, Anti-NR1D2, Anti-EAR-1R, Anti-Rev-erb-beta, Anti-Rev-erb alpha-related receptor, Anti-V-erbA-related protein... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
From 358.00€
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Item number: ELK-ELK6172.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NR1D2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NR1D2. Next,...
Keywords: | EAR4, Rev-erb-beta, Nuclear receptor subfamily 1 group D member 2 |
Application: | ELISA |
Species reactivity: | rat |
From 374.00€
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Item number: ABS-PP-7708.20
Keywords: | Nuclear receptor subfamily 1 group D member 2, Orphan nuclear hormone receptor BD73, Rev-erb alpha-related receptor, RVR,... |
Expressed in: | E.coli |
Origin: | human |
MW: | 16.5 kD |
From 90.00€
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Item number: 039113.200
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described....
Keywords: | Anti-RVR, Anti-NR1D2, Anti-EAR-1R, Anti-Rev-erb-beta, Anti-Rev-erb alpha-related receptor, Anti-V-erbA-related protein... |
Application: | ELISA, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
767.00€
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Item number: ATA-APrEST85751.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | RVR, NR1D2, EAR-1R, Rev-erb-beta, Rev-erb alpha-related receptor, V-erbA-related protein 1-related, Orphan nuclear hormone... |
Application: | Control antigen |
Expressed in: | E.coli |
Origin: | human |
265.00€
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Item number: ATA-APrEST89708.100
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | RVR, NR1D2, EAR-1R, Rev-erb-beta, Rev-erb alpha-related receptor, V-erbA-related protein 1-related, Orphan nuclear hormone... |
Application: | Control antigen |
Expressed in: | E.coli |
Origin: | human |
265.00€
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Item number: G-CAB20447.20
Protein function: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the...
Keywords: | Anti-RVR, Anti-NR1D2, Anti-EAR-1R, Anti-Rev-erb-beta, Anti-Rev-erb alpha-related receptor, Anti-V-erbA-related protein... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
149.00€
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