230 products were found matching "K08530"!
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Rosiglitazone
Item number: Cay71740-10
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
| Keywords: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Application: | PPARgamma agonist |
| CAS | 122320-73-4 |
| MW: | 357.4 D |
From 43.00€
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NEW
FX-909
Item number: Cay41452-1
FX-909 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It inhibits the growth of urothelial cancer cells in vitro.Formal Name: 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile. CAS Number: 2924573-90-8. Molecular Formula: C17H10F2N2O3S. Formula...
| Keywords: | 3-(5,7-difluoro-1,4-dihydro-4-oxo-2-quinolinyl)-4-(methylsulfonyl)-benzonitrile |
| Application: | PPARgamma inverse agonist |
| CAS | 2924573-90-8 |
| MW: | 360.3 D |
From 108.00€
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BAY-0069
Item number: Cay41525-10
BAY-0069 is a peroxisome proliferator-activated receptor gamma (PPARgamma) inverse agonist. It acts as an inverse agonist in a co-repressor reporter assay with a peptide from nuclear receptor co-repressor 2 (NCOR2, EC50 = 9.6 nM). BAY-0069 selectively induces PPARgamma- over PPARalpha- or PPARdelta-mediated gene...
| Keywords: | 2-bromo-N-[2-(4-ethylphenyl)-5-benzoxazolyl]-5-nitro-benzamide |
| Application: | PPARgamma inverse agonist |
| CAS | 420826-65-9 |
| MW: | 466.3 D |
From 90.00€
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GW 9662
Item number: Cay70785-10
The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...
| Keywords: | 2-chloro-5-nitrobenzanilide |
| Application: | Irreversible PPARgamma antagonist |
| CAS | 22978-25-2 |
| MW: | 276.7 D |
From 16.00€
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Pioglitazone potassium
Item number: TGM-T61836-10mg
Description: Pioglitazone potassium (U 72107) is an orally active, selective agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), exhibiting high-affinity binding to the ligand-binding domain of PPARgamma with EC50 values of 0.93 µM for human and 0.99 µM for mouse PPARgamma. It has applications...
| Application: | PPARgamma agonist |
| CAS | 1266523-09-4 |
| MW: | 394.53 D |
From 72.00€
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Rosiglitazone potassium
Item number: TGM-T61848-100mg
Description: Rosiglitazone (BRL 49653) potassium, a potent and selective PPARgamma agonist (EC 50: 60 nM, Kd: 40 nM) administered orally, also acts as an activator of TRPC5 (EC 50: 30 µM) and an inhibitor of TRPM3. Widely used in research, it has shown promise in investigating obesity, diabetes, senescence, and...
| Application: | PPARgamma agonist |
| CAS | 316371-84-3 |
| MW: | 395.52 D |
From 77.00€
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Lobeglitazone
Item number: TGM-T69011-100mg
Description: Lobeglitazone, also known as CKD-501, is an antidiabetic drug in the thiazolidinedione class of drugs. As an agonist for both PPARalpha and PPARgamma, it works as an insulin sensitizer by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Target: Others. Smiles:...
| Application: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 607723-33-1 |
| MW: | 480.54 D |
From 1,491.00€
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Oleuropein
Item number: TGM-T6917-100mg
Description: Oleuropein is an antioxidant polyphenol isolated from olive leaf. Target: ROS, Apoptosis, PPAR, Aromatase. Smiles: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc1ccc(O)c(O)c1. References: Visioli F, et al. Life Sci. 1998,62(6), 541-546.
| Application: | Antioxidant, free radical-scavenger, PPAR gamma antagonist |
| CAS | 32619-42-4 |
| MW: | 540.51 D |
From 43.00€
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Punicic acid
Item number: TGM-T78472-10mg
Description: Punicic acid, a conjugated isomer of alpha-linolenic acid and a omega-5 polyunsaturated fatty acid found in pomegranate seed oil, holds potential for research into various chronic diseases [1]. Target: Others. Smiles: C(C/C=C\C=C\C=C/CCCC)CCCCCC(O)=O
| Keywords: | Trichosanic acid |
| Application: | omega-5 long-chain PUFA, PPARgamma ligand |
| CAS | 544-72-9 |
| MW: | 278.43 D |
From 193.00€
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Mavodelpar
Item number: TGM-T73088-100mg
Description: Mavodelpar (REN001), a selective PPARdelta agonist, effectively suppresses glomerular injury and renal fibrosis. It is utilized in the research of primary mitochondrial myopathies (PMM) and long-chain fatty acid oxidation disorders (LC-FAOD). Target: Others. Smiles:...
| Keywords: | REN001 , HPP593, HPP593, REN001 |
| Application: | Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG) |
| CAS | 1604815-32-8 |
| MW: | 537.55 D |
From 1,638.00€
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NPC 15199
Item number: TGM-T8638-500mg
Description: NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent. Target: Others. Smiles: CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O. References: Jan C R , Yu C C , Huang J K . NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells[J]....
| Keywords: | FMOC-L-Leucine |
| Application: | PPARgamma modulator |
| CAS | 35661-60-0 |
| MW: | 353.41 D |
30.00€
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10,13-epoxy-11-methyl-Octadecadienoic Acid
Item number: TGM-T85012-10mg
Target: Others. Smiles: C(CCCCCCCC(O)=O)C=1OC(CCCCC)=CC1C
| Keywords: | F2 Furan Fatty Acid |
| Application: | Furan fatty acid, PPARG agonist |
| CAS | 57818-39-0 |
| MW: | 308.5 D |
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