15 products were found matching "K08428"!
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JNJ-63533054
Item number: TGM-T3119-100mg
Description: JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. Target: GPR. Smiles: C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1. References: Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20,6(9):1015-8.
| Keywords: | JNJ 63533054 |
| Application: | GPR139 agonist |
| CAS | 1802326-66-4 |
| MW: | 316.78 D |
From 31.00€
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TAK-041
Item number: TGM-T9317-100mg
Description: TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist. Target: GPR. Smiles: C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccc(OC(F)(F)F)cc1. References: Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with...
| Keywords: | NBI-1065846 |
| Application: | GPR139 agonist |
| CAS | 1929519-13-0 |
| MW: | 392.33 D |
From 31.00€
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Anti-GPR139
Item number: CSB-PA007021.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
126.00€
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TC-O 9311
Item number: Cay14030-1
TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay). It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 µM) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA, Cay-25330),...
| Keywords: | 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide |
| Application: | Potent GPR139 agonist |
| CAS | 444932-31-4 |
| MW: | 365.4 D |
From 44.00€
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JNJ-63533054
Item number: Cay23450-1
JNJ-63533054 is a potent agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 16 nM in HEK293 cells expressing human GPR139). It is selective for GPR139 over 50 known G protein-coupled receptors, ion channels, and transporters as determined by an external selectivity panel. Tritium-labeled JNJ-63533054...
| Keywords: | 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]-benzamide |
| Application: | GPR139 agonist |
| CAS | 1802326-66-4 |
| MW: | 316.8 D |
From 44.00€
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Anti-GPR139
Item number: E-AB-18037.120
This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript...
| Keywords: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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Anti-GPR139
Item number: ATA-HPA046596.100
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Keywords: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 239.00€
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TAK-041
Item number: Cay36108-1
TAK-041 is an agonist of G protein-coupled receptor 139 (GPR139). It induces calcium mobilization in cells expressing human GPR139 (EC50 = 22 nM). In vivo, TAK-041 (0.3 and 3 mg/kg) increases social interaction in mice.Formal Name:...
| Keywords: | NBI 1065864, 4-oxo-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]-1,2,3-benzotriazine-3(4H)-acetamide |
| Application: | GPR139 agonist |
| CAS | 1929519-13-0 |
| MW: | 392.3 D |
From 44.00€
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GP139 (human) full length protein-synthetic nanodisc
Item number: DIM-FLP100263.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Keywords: | GPRG1, GPR139, G-protein-coupled receptor PGR3, G(q)-coupled orphan receptor GPRg1, Probable G-protein coupled receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 40.7 kD |
From 1,291.00€
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Anti-GPR139 (Probable G-protein Coupled Receptor 139,...
Item number: G8601-43C.100
Orphan receptor. Seems to act through a G(q/11)-mediated pathway. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:4000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid...
| Application: | ELISA |
| Host: | Goat |
| Species reactivity: | human, mouse, rat |
543.00€
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GPR139 PrEST Antigen
Item number: ATA-APrEST77938.100
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Keywords: | GPRG1, GPR139, G-protein-coupled receptor PGR3, G(q)-coupled orphan receptor GPRg1, Probable G-protein coupled receptor 139 |
| Application: | Control antigen |
| Expressed in: | E.coli |
| Origin: | human |
265.00€
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Anti-GPR139
Item number: G-CAB15946.20
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium]
| Keywords: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
149.00€
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