46 products were found matching "K08362"!
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THRB Protein, Human, Recombinant (His & SUMO)
Item number: TGM-TMPH-02204-100ug
Description: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
| Keywords: | c-erbA-beta, THRB, Thyroid hormone receptor beta, c-erbA-2, Nuclear receptor subfamily 1 group A member 2 |
| MW: | 68.8 kD |
From 198.00€
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Triiodothyronine-13C6 hydrochloridehydrochloride
Item number: TGM-TMID-0105-1mg
Description: 3,3',5-Triiodothyronine-(tyrosine ring-13C6) hydrochloride is the 13C labeled compound of 3,3',5-Triiodothyronine hydrochloride. Smiles: O([13C]1=[13C](I)[13CH]=[13C](C[C@@H](C(O)=O)N)[13CH]=[13C]1I)C2=CC(I)=C(O)C=C2.Cl
| Keywords: | 3,3',5-Triiodothyronine-(tyrosine ring-13C6) |
| Application: | Thyroxine, LC/MS internal standard |
| CAS | 1217473-60-3 |
| MW: | 693.39 D |
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THRB Protein, Human, Recombinant (His)
Item number: TGM-TMPY-06821-50ug
Description: Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and...
| Keywords: | THRB1, GRTH, C-ERBA-2, ERBA2, THR1, THRB2, NR1A2, C-ERBA-BETA, C-ERBA-beta, thyroid hormone receptor, beta, thyroid... |
| MW: | 30.33 kD |
599.00€
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L-Thyroxine sodium salt pentahydrate
Item number: TGM-T15699-1mL
Description: L-Thyroxine sodium salt pentahydrate, also known as Levothyroxine, is a synthetic hormone utilized in the study of hypothyroidism. It is biologically activated into Triiodothyronine (T3) from its original form, L-Thyroxine (T4), through conversion by DIO enzymes. Target: Thyroid hormone receptor(THR)....
| Keywords: | Sodium levothyroxine pentahydrate, Levothyroxine |
| Application: | Thyroid hormone receptor agonist |
| CAS | 6106-07-6 |
| MW: | 888.93 D |
49.00€
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MB-07811
Item number: TGM-T16018-10mg
Description: MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB-07344, known for its cholesterol and triglycerides lowering activity and its function as a liver-targeted THR-beta agonist. Target: Thyroid hormone receptor(THR). Smiles:...
| Keywords: | VK-2809 |
| Application: | Liver-targeted MB-07344 prodrug |
| CAS | 852948-13-1 |
| MW: | 514.98 D |
From 94.00€
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Resmetirom
Item number: TGM-T3595-100mg
Description: Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor beta (THR-beta) agonist. Target: Thyroid hormone receptor(THR). Smiles: CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O. References: Kelly, M., Pietranico-Cole, S., Larigan, J., Haynes, N., Reynolds, C., & Scott, N. et al....
| Keywords: | MGL3196, VIA-3196 |
| Application: | Targets thyroid hormone receptor beta (THRB, NR1A2) |
| CAS | 920509-32-6 |
| MW: | 435.22 D |
From 34.00€
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3,5-Diiodo-L-thyronine
Item number: TGM-T4461-100mg
Description: 3,5-Diiodo-L-thyronine (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis, lipid metabolism and insulin resistance. Target: Thyroid hormone receptor(THR), Endogenous Metabolite. Smiles: N[C@@H](Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)C(O)=O....
| Keywords: | Diiodothyronine |
| Application: | Thyroid hormone metabolite |
| CAS | 1041-01-6 |
| MW: | 525.08 D |
30.00€
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Sobetirome
Item number: TGM-T5313-100mg
Description: Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor beta (TRbeta) and binds selectively to TRbeta-1 (EC50: 0.16 µM). Target: Thyroid hormone receptor(THR). Smiles: CC(C)c1cc(Cc2c(C)cc(OCC(O)=O)cc2C)ccc1O. References: Gierach I, et al. Bacterial biosensors for screening...
| Keywords: | QRX-431, GC 1, GC-1, IACS-010759, GC1 |
| Application: | Targets thyroid hormone receptor beta (THRB, NR1A2) |
| CAS | 211110-63-3 |
| MW: | 328.4 D |
From 42.00€
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Thyroid hormone receptor beta (THRB), human, recombinant
Item number: CSB-EP023514HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-461aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MTPNSMTENG LTAWDKPKHC PDREHDWKLV GMSEACLHRK SHSERRSTLK NEQSSPHLIQ TTWTSSIFHL DHDDVNDQSV SSAQTFQTEE KKCKGYIPSY LDKDELCVVC GDKATGYHYR CITCEGCKGF...
| Keywords: | THRB, ERBA2, c-erbA-2, c-erbA-beta, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 68.8 kD |
From 219.00€
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3,3',5-Triiodo-L-thyronine (sodium salt hydrate)
Item number: Cay16028-100
3,3',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5'-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRalpha and TRbeta (Kis = 2.3 nM for both) that modulates diverse biological properties, including...
| Keywords: | L-3,3',5-Triiodothyronine, Liothyronine, T3, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, monosodium salt, hydrate |
| Application: | Thyroid hormone receptor agonist |
| CAS | 345957-19-9 |
| MW: | 673 D |
From 61.00€
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Tiratricol
Item number: Cay28729-50
Tiratricol is a metabolite of 3,3',5-triiodo-L-thyronine (Cay-16028) and an agonist of the thyroid hormone receptors TRalpha and TRbeta (EC50s = 1.81 and 4.13 nM, respectively, in reporter assays). In vivo, tiratricol (50 or 400 ng/g) stimulates cerebellar Purkinje cell dendritogenesis and cortical myelination in...
| Keywords: | 3,3',5-Triiodothyroacetic acid, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-benzeneacetic acid |
| Application: | Thyroid hormone receptor agonist, T3 metabolite |
| CAS | 51-24-1 |
| MW: | 621.9 D |
From 44.00€
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Anti-Thyroid Hormone Receptor beta, clone 2386
Item number: 209-301-A96
Anti-Thyroid Hormone Receptor beta antibody is directed against human TR?. Thyroid Hormone Receptor beta antibody is purified by Protein G chromatography. This antibody is specific for the human protein. Cross reactivity from other sources has not been determined. Protein function: High affinity receptor for...
| Keywords: | Anti-THRB, Anti-ERBA2, Anti-c-erbA-2, Anti-c-erbA-beta, Anti-Thyroid hormone receptor beta, Anti-Nuclear receptor... |
| Application: | WB |
| Host: | Mouse |
| Species reactivity: | human |
867.00€
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