11 products were found matching "K07413"!

(S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19, also known as mephenytoin 4-hydroxylase. CYP2C19 metabolizes a variety of therapeutic agents, including omeprazole, proguanil, diazepam, propranolol, citalopram, imipramine, and certain barbiturates. Genetic defects in CYP2C19 result in...

Description: 6alpha-hydroxy Paclitaxel (6alpha-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic. Target: Drug Metabolite. Smiles:...

Description: cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous component in human urine and blood, produced from oleic acid through enzymic and non-enzymic epoxidation. Target: Endogenous Metabolite. Smiles: CCCCCCCC[C@H]1O[C@H]1CCCCCCCC(O)=O. References: Tsikas D, et al. Gas...

Description: (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsant that serves as a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and is used to analyze cytochrome P450 metabolism. Target: Others. Smiles: CCC1(NC(=O)N(C)C1=O)c1ccccc1

Cytochrome P450 enzymes function to metabolize both endogenous and exogenous compounds. Both the 3A and 2C isoforms are present in human liver of which CYP2C9 seems most highly expressed. Tienilic acid is a specific suicide substrate for CYP2C9 and CYP2C10 whereby its oxidation inactivates the enzyme. The time...

cis-9,10-Epoxyoctadecanoic acid is an epoxy fatty acid. It is an oxidation product of oleic acid formed by the cytochrome P450 (CYP) isoforms CYP2C and CYP3A. It has been found in the fungus P. carinii isolated from the lungs of rats in a model of P. carinii-induced pneumonia. cis-9,10-Epoxyoctadecanoic acid has...

6alpha-hydroxy Paclitaxel is a metabolite of the antimitotic and anticancer agent paclitaxel (Cay-10461). It is formed from paclitaxel by the cytochrome P450 (CYP) isoform CYP2C8.Formal Name:...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....