402 products were found matching "K07375"!

Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...

Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. Binding of NTN1/Netrin-1 to its receptor UNC5C might...

OG488 Taxol Conjugate is the same compound as Oregon Green(R) 488 paclitaxel (also known as Flutax-2). Taxol, also known as Paclitaxel, is an anticancer agent. Taxol is known to promote tubulin assembly into stable aggregated structures. The green fluorescent OG488 Taxol Conjugate is an effective fluorescent probe...

OG488 Diacetate Taxol Conjugate is the same compound as Oregon GreenTM 488 Taxol, bis-acetate. Taxol, also known as Paclitaxel, is an anticancer agent. Taxol is known to promote tubulin assembly into stable aggregated structures. The OG488 Diacetate Taxol Conjugate is an effective fluorescent probe for studying...

Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]

Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....

In eukaryotes there are six members of the tubulin superfamily. alpha- and beta-tubulins polymerize into microtubules,a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes,including mitosis. Both alpha and beta tubulins have a mass of around 50 kDa. Tubulin was...

In eukaryotes there are six members of the tubulin superfamily. alpha- and beta-tubulins polymerize into microtubules,a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes,including mitosis. Both alpha and beta tubulins have a mass of around 50 kDa. Tubulin was...

In eukaryotes there are six members of the tubulin superfamily. alpha- and beta-tubulins polymerize into microtubules,a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes,including mitosis. Both alpha and beta tubulins have a mass of around 50 kDa. Tubulin was...

In eukaryotes there are six members of the tubulin superfamily. alpha- and beta-tubulins polymerize into microtubules,a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes,including mitosis. Both alpha and beta tubulins have a mass of around 50 kDa. Tubulin was...

In eukaryotes there are six members of the tubulin superfamily. alpha- and beta-tubulins polymerize into microtubules,a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes,including mitosis. Both alpha and beta tubulins have a mass of around 50 kDa. Tubulin was...

7-acetyl Paclitaxel is an inhibitor of microtubule depolymerization. It inhibits calcium-induced microtubule depolymerization when used at a concentration of 10 µM. 7-acetyl Paclitaxel reduces the growth of J774.2 macrophages (IC50 = ~60 nM). It also increases the levels of nitric oxide (NO) and TNF in isolated...