103 products were found matching "K06487"!
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alphavbeta5 integrin-IN-1
Item number: TGM-T40243-1mg
Description: alphavbeta5 integrin-IN-1, a potent and selective alphavbeta5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2. Target: Others. Smiles: OC(=O)C[C@H](C(=O)N1CC[C@@H](CCC2=CC=C3CCCN=C3N2)C1)c1cccc(c1)C(F)(F)F , c:20,t:13,15, . References: Lippa RA, et al. Discovery of the...
| Application: | AlphaVbeta5 integrin inhibitor |
| CAS | 2615912-33-7 |
| MW: | 475.512 D |
742.00€
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GLPG0187
Item number: TGM-T4259-100mg
Description: GLPG0187, a broad spectrum integrin receptor antagonist, inhibits alphavbeta1-integrin (IC50: 1.3 nM). Target: Integrin. Smiles: COc1ccc(cc1)S(=O)(=O)N[C@@H](CNc1nc(C)nc(N2CCC(CC2)C2=CC=C3CCCN=C3N2)c1C)C(O)=O. References: van der Horst G, et al. Targeting of alpha(v)-integrins in stem/progenitor cells...
| Application: | ITGAV antagonist |
| CAS | 1320346-97-1 |
| MW: | 595.71 D |
From 40.00€
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CWHM-12
Item number: TGM-TQ0250-100mg
Description: CWHM-12 is a potent inhibitor of alphaV integrins, with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for alphavbeta8, alphavbeta3, alphavbeta6, and alphavbeta1, respectively. Target: Integrin. Smiles: CC(C)(C)c1cc(Br)cc(c1)[C@H](CC(O)=O)NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1. References: Henderson NC, et...
| Application: | Integrin alpha-V inhibitor |
| CAS | 1564286-55-0 |
| MW: | 590.47 D |
From 34.00€
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Integrin alpha-V (ITGAV), partial, human, recombinant
Item number: CSB-YP011877HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 891-1048aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: DLALSEGDIH TLGCGVAQCL KIVCQVGRLD RGKSAILYVK SLLWTETFMN KENQNHSYSL KSSASFNVIE FPYKNLPIED ITNSTLVTTN VTWGIQPAPM PVPVWVIILA VLAGLLLLAV LVFVMYRMGF FKRVRPPQEE...
| Keywords: | Recombinant Human Integrin alpha-V (ITGAV), partial |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 19.7 kD |
From 242.00€
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Human ITGAV and ITGB1 Heterodimer Protein, His Tag and...
Item number: DIM-PME100861.10
Recombinant heterodimer protein containg both human ITGAV Protein with C-terminal 6×His tag and human ITGB1 protein with C-terminal human Fc tag. ITGAV(Phe31-Val992) 6×His tag - ITGB1(Gln21-Asp728) hFc(Glu99-Ala330), Protein function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin,...
| Keywords: | Integrin alpha V beta 1, ITGAVandITGB1 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 107.1/ kD |
From 172.00€
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Human ITGAV and ITGB6 Heterodimer Protein, His Tag and...
Item number: DIM-PME101386.10
Recombinant human ITGAV protein with C-terminal 6×His tag and human ITGB6 protein with C-terminal human Fc tag. ITGAV(Phe31-Val992) 6×His tag and ITGB6(Gly22-Asn707) hFc(Glu99-Ala330), Protein function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix...
| Keywords: | CD51, MSK8, VNRA, VTNR and AI1H |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 107.1/ kD |
From 113.00€
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Human ITGAV and ITGB5 Heterodimer Protein, His Tag and...
Item number: DIM-PME101467.10
Recombinant human ITGAV protein with C-terminal 6×His tag and human ITGB5 protein with C-terminal human Fc tag. ITGAV(Phe31-Val992) 6×His tag and ITGB5(Gly24-Asn719) hFc(Glu99-Ala330), Protein function: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix...
| Keywords: | CD51, MSK8, VNRA, VTNR and ITB5, Integrin beta-5 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 107.1/ kD |
From 136.00€
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Anti-ITGAV
Item number: CSB-PA003047.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | antigen identified by monoclonal antibody L230 antibody, CD 51 antibody, CD51 antibody, DKFZp686A08142 antibody, Integrin... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 126.00€
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Anti-Cleaved-ITGAV (K889)
Item number: CSB-PA000074.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | antigen identified by monoclonal antibody L230 antibody, CD 51 antibody, CD51 antibody, DKFZp686A08142 antibody, Integrin... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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CWHM12
Item number: Cay19480-5
CWHM12 is an analog of RGD peptide (Cay-14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation. CWHM12 selectively inhibits alphav integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for alphavbeta1, alphavbeta3, alphavbeta5,...
| Keywords: | (3S)-N-[3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-[3-bromo-5-(1,1-dimethylethyl)phen... |
| Application: | Integrin alpha-V inhibitor |
| CAS | 1564286-55-0 |
| MW: | 590.5 D |
From 52.00€
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Cilengitide
Item number: Cay22289-10
Cilengitide is a cyclo-(Arg-Gly-Asp-D-Phe-Val) (cRGDfV) peptide and integrin alphaVbeta3 receptor antagonist. It inhibits adhesion and induces apoptosis of U87MG and U373MG malignant glioma (MG) cells, but not U251MG cells that lack the integrin alphaVbeta3 receptor, in vitro at a concentration of 20 µg/ml....
| Keywords: | EMD 121974, cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl) |
| Application: | Integrin alphaVbeta3 receptor antagonist |
| CAS | 188968-51-6 |
| MW: | 588.7 D |
From 45.00€
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GLPG0187
Item number: Cay21792-5
GLPG0187 is a nonpeptide antagonist of alphanu integrin receptors (IC50s = 1.2-3.7 nM). It inhibits osteoclastogenesis, bone resorption, and angiogenesis in vitro and in vivo in mice, which are all hallmarks of bone marrow invasion in metastatic prostate cancer. GLPG0187 reduces epithelial-mesenchymal transition...
| Keywords: | 3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)s... |
| Application: | ITGAV antagonist |
| CAS | 1320346-97-1 |
| MW: | 595.7 D |
From 67.00€
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