307 products were found matching "K06067"!
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SAHA
Item number: Cay10009929-100
SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.Formal Name:...
| Keywords: | Suberoylanilide Hydroxamic Acid, Vorinostat, N1-hydroxy-N8-phenyl-octanediamide |
| Application: | HDAC inhibitor |
| CAS | 149647-78-9 |
| MW: | 264.3 D |
From 35.00€
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HDAC-1, active human recombinant protein
Item number: BPS-50051
Active human HDAC1, GenBank Accession No. NM_004964, full length with C-terminal HIS-DDDDK tag (FLAG), MW= 56 kDa, expressed in baculovirus expression system.
| Keywords: | HD1, Histone deacetylase 1, Protein deacetylase HDAC1, Protein decrotonylase HDAC1, |
| Application: | Enzyme kinetics, inhibitor screening |
| MW: | 56 kD |
730.00€
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Trichostatin A
Item number: Cay89730-1
Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the...
| Keywords: | TSA, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide |
| Application: | HDAC inhibitor |
| CAS | 58880-19-6 |
| MW: | 302.4 D |
From 77.00€
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Anti-HDAC1
Item number: ABS-KC-6056.100
Protein function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone...
| Keywords: | Anti-Histone deacetylase 1, Anti-HD1, Anti-Protein deacetylase HDAC1, Anti-Protein decrotonylase HDAC1, HDAC1 Antibody |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human, rat, mouse |
From 206.00€
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Valproic Acid (sodium salt)
Item number: Cay13033-10
Valproic acid is an analog of the natural fatty acid valeric acid that inhibits class I histone deacetylases (HDACs) with an IC50 value of approximately 2 mM. It decreases the number of axon branches in sensory neurons isolated from newborn rat dorsal root ganglia, an effect that is reversed by...
| Keywords: | 2-Propylvaleric Acid, Valproate, VPA, 2-propyl-pentanoic acid, monosodium salt |
| Application: | HDAC inhibitor |
| CAS | 1069-66-5 |
| MW: | 166.2 D |
From 52.00€
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GSK-J1
Item number: TGM-T6847-100mg
Description: GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases. Target: Histone Demethylase. Smiles: OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1....
| Keywords: | GSK J1 |
| Application: | pan-HDAC inhibitor (HDAC1, 2, 4, 10, 11) |
| CAS | 1373422-53-7 |
| MW: | 389.45 D |
From 42.00€
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Quisinostat dihydrochloride
Item number: TGM-T6865-100mg
Description: Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to...
| Keywords: | Quisinostat 2HCl, Quisinostat (JNJ-26481585) 2HCl, JNJ26854165(Quisinostat) 2HCl, JNJ-26481585 2HCl |
| Application: | HDAC inhibitor |
| CAS | 875320-31-3 |
| MW: | 467.39 D |
From 60.00€
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Scriptaid
Item number: TGM-T6980-100mg
Description: Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3. Target: Apoptosis, HDAC, Autophagy, Influenza Virus. Smiles: O=C1C=2C=3C(C(=O)N1CCCCCC(NO)=O)=CC=CC3C=CC2. References: Su GH, et al. Cancer Res, 2000, 60(12), 3137-3142.
| Keywords: | GCK1026, Scriptide |
| Application: | Histone deacetylase inhibitor |
| CAS | 287383-59-9 |
| MW: | 326.35 D |
From 65.00€
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Pyroxamide
Item number: TGM-T7664-100mg
Description: Pyroxamide is an histone deacetylases (HDACs) inhibitor with antineoplastic properties ( HDAC1,IC50: 0.1-0.2 µM). Target: HDAC, Apoptosis. Smiles: ONC(=O)CCCCCCC(=O)Nc1cccnc1. References: Butler L M , Webb Y , Agus D B , et al. Inhibition of transformed cell growth and induction of cellular...
| Application: | Histone deacetylases Inhibitor |
| CAS | 382180-17-8 |
| MW: | 265.31 D |
From 43.00€
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NSC 3852
Item number: TGM-T7691-100mg
Description: NSC 3852 is a potent inhibitor of histone deacetylase. Target: HDAC. Smiles: OC1=C2N=CC=CC2=C(C=C1)N=O. References: Jeannine S. Strobl, Christopher W. Seibert, Yunbo Li, Rana Nagarkatti, Sheila M. Mitchell, Alexa C. Rosypal, Dharmendar Rathore, and David S. Lindsay. Inhibition of Toxoplasma gondii and...
| Application: | HDAC inhibitor |
| CAS | 3565-26-2 |
| MW: | 174.16 D |
From 52.00€
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HDAC-IN-3
Item number: TGM-T8508-100mg
Description: HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders. Target: HDAC. Smiles: ONC(=O)CCc1ccc(CN[C@@H](C2CCCCC2)C(=O)OC2CCCC2)cn1. References: Davidson Alan Hornsby, et al. Preparation of amino acid-based hydroxamic acids as histone...
| Keywords: | GSK3117391A |
| Application: | HDAC inhibitor |
| CAS | 1018673-42-1 |
| MW: | 403.52 D |
From 42.00€
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HDAC1 Protein, Human, Recombinant (His & SUMO)
Item number: TGM-TMPH-01471-100ug
Description: HDAC1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 71.1 kDa and the accession number is Q13547.
| Keywords: | Protein deacetylase HDAC1, Histone deacetylase 1, Protein decrotonylase HDAC1, HDAC1 |
| MW: | 71.1 kD |
From 198.00€
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