65 products were found matching "K05917"!

Lanosterol 14-alpha-demethylase, also known as cytochrome P450 (CYP) isoform CYP51A1, is a heme-containing demethylase and member of the CYP450 superfamily that demethylates lanosterol (Cay-19521) to generate sterol precursors in the synthesis of cholesterol (Cay-39088, Cay-9003100). It is ubiquitously expressed...

Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: Baculovirus. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL...

Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: E.coli. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL DQAKAYPFMT PIFGEGVVFD ASPERRKEML...

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). Source: E.coli. Expression Region: 1-20aa. Protein Length: Extracellular Domain. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSATKSIVGE ALEYVNIGLS. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test....

Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh). Source: Yeast. Expression Region: 1-451aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MSAVALPRVS GGHDEHGHLE EFRTDPIGLM QRVRDECGDV GTFQLAGKQV VLLSGSHANE FFFRAGDDDL DQAKAYPFMT...

Ketoconazole is a broad-spectrum triazole antifungal agent that has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans, and A. fumigatus strains (IC50s = 0.031-8 µg/ml). It inhibits the fungal cytochrome P450 (CYP) isoform CYP51, also known as lanosterol...

Difenoconazole-d6 is intended for use as an internal standard for the quantification of difenoconazole (Cay-24053) by GC- or LC-MS. Difenoconazole is a triazole fungicide. It is active against eight F. graminearum isolates (EC50s = 1.69-19.6 mg/L) and A. sonali, F. fulva, B. cinerea, and R. solani (EC50s = 0.131,...

An inhibitor of cytochrome P-450 in steroid biosynthesis, and an inhibitor of lipoxygenase and thromboxane synthase activities. It is classified as antineoplastic, antimetastatic, and antipsoriatic.

Fluconazole is a triazole antifungal agent that is effective against most Candida strains. In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis,...

Posaconazole is a broad-spectrum triazole antifungal agent active against various yeasts and molds, including Aspergillus, Candida, Fusarium, and Zygomycetes. Posaconazole inhibits the growth of fungi by inhibiting the lanosterol 14alpha-demethylase enzyme (IC50s = 7-200 nM), which results in a disruption in the...

Voriconazole-d3 is intended for use as an internal standard for the quantification of voriconazole (Cay-15633) by GC- or LC-MS. Voriconazole is a triazole antifungal agent and a derivative of fluconazole (Cay-11594). It is active against a variety of yeast and fungi, including clinical isolates of A. flavus, A....

Imazalil-d5 (sulfate) is intended for use as an internal standard for the quantification of imazalil (Cay-25815) by GC- or LC-MS. Imazalil is an imidazole fungicide that inhibits ergosterol biosynthesis. Imazalil inhibits the growth of various fungi in vitro including P. italicum, A. niger, U. maydis, B. alii, and...