115 products were found matching "K05917"!
No results were found for the filter!
Pramiconazole
Item number: TGM-T25982-100mg
Description: Pramiconazole (R126638) is an orally available antifungal compound.Pramiconazole is a candidate for the treatment of dermatophytes and cutaneous yeast infections in seborrheic dermatitis. Target: Antifungal. Smiles:...
| Keywords: | R 126638, Azoline, R126638, R-126638 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 219923-85-0 |
| MW: | 659.73 D |
From 541.00€
*
Sertaconazole nitrate
Item number: TGM-T6665-100mg
Description: Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections. Target: Antibiotic, Antifungal. Smiles: O[N+]([O-])=O.Clc1ccc(C(Cn2ccnc2)OCc2csc3c(Cl)cccc23)c(Cl)c1. References: Liebel F,...
| Keywords: | Ginedermofix, FI-7045, FI7056, Ertaczo |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 99592-39-9 |
| MW: | 500.78 D |
From 40.00€
*
Sulconazole mononitrate
Item number: TGM-T6686-100mg
Description: Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and...
| Keywords: | Exelderm, Sulconazole Nitrate, RS 44872 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 61318-91-0 |
| MW: | 460.76 D |
From 31.00€
*
Isoconazole nitrate
Item number: TGM-T6550-100mg
Description: Isoconazole nitrate (Fazol) (Travogen) is an azole antifungal reagent. Target: Antibacterial, Antibiotic, Antifungal. Smiles: O[N+](=O)[O-].Clc1cc(Cl)c(cc1)C(Cn1ccnc1)OCc1c(Cl)cccc1Cl. References: Veraldi S.Mycoses. 2013 May,56 Suppl 1:41-3.
| Keywords: | Fazol, Travogyn |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 24168-96-5 |
| MW: | 479.14 D |
From 31.00€
*
Fenticonazole Nitrate
Item number: TGM-T6499-100mg
Description: Fenticonazole Nitrate (Lomexin) is an azole agent with antifungal activity. Target: Antifungal, Antibiotic. Smiles: c1ccc(cc1)Sc1ccc(cc1)COC(Cn1ccnc1)c1c(cc(cc1)Cl)Cl.[N+](=O)(O)[O-]. References: Fernández-Alba J, et al.J Chemother. 2004 Apr,16(2):179-86.
| Keywords: | Lomexin, Falvin, REC 15-1476 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 73151-29-8 |
| MW: | 518.41 D |
From 30.00€
*
Sulconazole
Item number: TGM-T61885-100mg
Description: Sulconazole is an imidazole compound with effective antifungal effect. Sulconazole vs. NF- kappa B/IL-8 signal pathway has blocking effect and inhibiting effect on the formation of cancer stem cells (CSC). Sulconazole has inhibitory effect on tumor growth, which can be used in breast cancer research....
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 61318-90-9 |
| MW: | 397.75 D |
From 1,520.00€
*
Bifonazole
Item number: TGM-T1187-10g
Description: Bifonazole (Bay H-4502) acts to destabilize the fungal cytochrome p450 51 enzyme (also known as Lanosterol 14-alpha-demethylase). It works by inhibiting the production of a substance called ergosterol, which is an essential component of fungal cell membranes. This is vital in the cell membrane structure...
| Keywords: | Bay H-4502 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 60628-96-8 |
| MW: | 310.39 D |
From 31.00€
*
Fluconazole
Item number: TGM-T1388-100mg
Description: Fluconazole (UK-49858) is a triazole antifungal agent used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. Target: Antifungal, Antibiotic, Antifection. Smiles: OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1. References: Uppuluri P, et al. Antimicrob Agents Chemother, 2008, 52(3),...
| Keywords: | UK-49858 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 86386-73-4 |
| MW: | 306.27 D |
From 31.00€
*
Oxiconazole nitrate
Item number: TGM-T1290-100mg
Description: Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This...
| Keywords: | Ro 13-8996 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 64211-46-7 |
| MW: | 492.14 D |
From 37.00€
*
PC945
Item number: TGM-T12376-100mg
Description: PC945 (Opelconazole) is a potent broad-spectrum antifungal compound with inhibitory effect on fumonisinol 14alpha-demethylase (CYP51A/CYP51B), which can be used in the study of fungal infections of the lungs. Target: Others. Smiles:...
| Keywords: | Opelconazole |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 1931946-73-4 |
| MW: | 682.73 D |
From 139.00€
*
Tebuconazole
Item number: TGM-T17022-500mg
Description: Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 µM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively). Target: Antifungal, P450. Smiles: CC(C)(C)C(O)(CCc1ccc(Cl)cc1)Cn1cncn1. References: Warrilow AG, et al. Azole affinity of sterol...
| Application: | Conazole fungicide |
| CAS | 107534-96-3 |
| MW: | 307.82 D |
49.00€
*
Oteseconazole
Item number: TGM-T16412-100mg
Description: Oteseconazole (VT-1161) is an orally active anti-fungal agent. Oteseconazole displays no obvious effect on human CYP51. It also potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM). Target: P450, Antifungal. Smiles: O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(cn1)-c1ccc(OCC(F)(F)F)cc1....
| Keywords: | VT-1161 |
| Application: | Targets sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36] (CYP51) |
| CAS | 1340593-59-0 |
| MW: | 527.39 D |
From 93.00€
*