351 products were found matching "K05718"!
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Lifitegrast
Item number: TGM-T3977-100mg
Description: Lifitegrast (SAR 1118) is an antagonist of lymphocyte function-associated antigen-1. Target: Integrin. Smiles: CS(=O)(=O)c1cccc(C[C@H](NC(=O)c2c(Cl)cc3CN(CCc3c2Cl)C(=O)c2ccc3ccoc3c2)C(O)=O)c1. References: Perez VL, et al. Lifitegrast, a Novel Integrin Antagonist for Treatment of Dry Eye Disease. Ocul...
| Keywords: | SHP-606, SAR 1118 |
| Application: | Targets integrin alpha L (ITGAL, CD11a) |
| CAS | 1025967-78-5 |
| MW: | 615.48 D |
From 34.00€
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Integrin alpha-L (ITGAL), partial, human, recombinant
Item number: CSB-EP011875HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 150-336aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: CIKGNVDLVF LFDGSMSLQP DEFQKILDFM KDVMKKLSNT SYQFAAVQFS TSYKTEFDFS DYVKRKDPDA LLKHVKHMLL LTNTFGAINY VATEVFREEL GARPDATKVL IIITDGEATD SGNIDAAKDI IRYIIGIGKH...
| Keywords: | CD11a, CD11A, ITGAL, LFA-1A, Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 28.2 kD |
From 292.00€
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Integrin alpha-L (ITGAL), partial, human, recombinant
Item number: CSB-YP011875HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 150-336aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: CIKGNVDLVF LFDGSMSLQP DEFQKILDFM KDVMKKLSNT SYQFAAVQFS TSYKTEFDFS DYVKRKDPDA LLKHVKHMLL LTNTFGAINY VATEVFREEL GARPDATKVL IIITDGEATD SGNIDAAKDI IRYIIGIGKH...
| Keywords: | CD11a, CD11A, ITGAL, LFA-1A, Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1... |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 22.8 kD |
From 347.00€
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Integrin alpha-L (ITGAL), partial, human, recombinant
Item number: CSB-MP011875HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 150-336aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: CIKGNVDLVF LFDGSMSLQP DEFQKILDFM KDVMKKLSNT SYQFAAVQFS TSYKTEFDFS DYVKRKDPDA LLKHVKHMLL LTNTFGAINY VATEVFREEL GARPDATKVL IIITDGEATD SGNIDAAKDI...
| Keywords: | CD11a, CD11A, ITGAL, LFA-1A, Integrin alpha-L, CD11 antigen-like family member A, Leukocyte adhesion glycoprotein LFA-1... |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 50.2 kD |
From 371.00€
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Anti-ITGAL
Item number: CSB-PA006157.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-ITGAL
Item number: CSB-PA932598.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ITGAL. Antigen Species: Human
| Keywords: | Anti-CD11a, Anti-CD11A, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Lifitegrast (sodium salt)
Item number: Cay40427-10
Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...
| Keywords: | SAR 1118-023,... |
| Application: | LFA-1/ICAM-1 interaction inhibitor |
| CAS | 1119276-80-0 |
| MW: | 637.5 D |
From 90.00€
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Anti-CD11a (bovine), clone HUH73A
Item number: WS0586B-100
The monoclonal antibody was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
| Keywords: | Anti-CD11a, Anti-ITGAL, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A, Anti-Leukocyte... |
| Application: | FC, IHC, Cell Function |
| Host: | Mouse |
| Species reactivity: | bison, bovine, caprine, dog, human, ovine |
343.00€
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Anti-LFA-1
Item number: NSJ-R36394-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Lymphocyte function-associated antigen 1, CD11A, integrin alpha L (ITGAL) Protein function: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety...
| Keywords: | Anti-CD11A, Anti-ITGAL, Anti-CD11a, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | WB, IHC, ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
790.00€
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Lifitegrast
Item number: Cay22588-10
Lifitegrast is an inhibitor of the protein-protein interaction between lymphocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1 (ICAM-1). It binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits the...
| Keywords: | SAR 1118,... |
| Application: | CD11A blocker |
| CAS | 1025967-78-5 |
| MW: | 615.5 D |
From 44.00€
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Anti-CD11a / LFA-1
Item number: NSJ-R32698
0.5mg/ml if reconstituted with 0.2ml sterile DI water. CD11a, also known as ITGAL or LFA-1, is a human gene which functions in the immune system. It is mapped to 16p11.2. CD11a is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab. CD11a encodes the integrin alpha L...
| Keywords: | Anti-ITGAL, Anti-CD11a, Anti-CD11A, Anti-LFA-1A, Anti-Integrin alpha-L, Anti-CD11 antigen-like family member A,... |
| Application: | WB, FC, ICC |
| Host: | Rabbit |
| Species reactivity: | human |
772.00€
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Anti-CD11a / LFA-1 alpha, clone I21/7
Item number: ARG20829.100
| Keywords: | Anti-Integrin alpha-L |
| Application: | FC, IHC (frozen), ICC, IF, IP, BL |
| Host: | Rat |
| Species reactivity: | mouse |
586.00€
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