- Search results for K05658
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142 products were found matching "K05658"!
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NEW
Item number: CSB-EP001046HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 236-297aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: LSSFTDKELL AYAKAGAVAE EVLAAIRTVI AFGGQKKELE RYNKNLEEAK RIGIKKAITA NI. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological...
Keywords: | MDR1, CD243, EC=7.6.2.2, P-glycoprotein 1, Phospholipid transporter ABCB1, Multidrug resistance protein 1, ATP-dependent... |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 10.8 kD |
From 213.00€
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NEW
Item number: CSB-EP001046HU2.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 350-710aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: PSIEAFANAR GAAYEIFKII DNKPSIDSYS KSGHKPDNIK GNLEFRNVHF SYPSRKEVKI LKGLNLKVQS GQTVALVGNS GCGKSTTVQL MQRLYDPTEG MVSVDGQDIR TINVRFLREI IGVVSQEPVL FATTIAENIR...
Keywords: | MDR1, CD243, EC=7.6.2.2, P-glycoprotein 1, Phospholipid transporter ABCB1, Multidrug resistance protein 1, ATP-dependent... |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 44.2 kD |
From 213.00€
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NEW
Item number: DIM-PME100589.10
Recombinant Human MDR-1 with C-terminal human Fc tag. MDR-1(Phe72-Arg113) (Lys213-Thr215) (Thr318-Gln330) (Gly960-Asp973) hFc(Glu99-Ala330), Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the...
Keywords: | ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 |
Expressed in: | Human cells |
Origin: | human |
CAS | 12 |
MW: | 34.2 kD |
From 101.00€
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NEW
Item number: DIM-PME100601.10
Recombinant Human MDR-1(Phe72-Arg113) with C-terminal human Fc tag. MDR-1(Phe72-Arg113) hFc(Glu99-Ala330), Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of...
Keywords: | ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 |
Expressed in: | Human cells |
Origin: | human |
CAS | 12 |
MW: | 30.9 kD |
From 95.00€
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NEW
Item number: DIM-FLP100029.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Keywords: | MDR1, CD243, EC=7.6.2.2, P-glycoprotein 1, Phospholipid transporter ABCB1, Multidrug resistance protein 1, ATP-dependent... |
Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Expressed in: | Human cells |
Origin: | human |
MW: | 141.5 kD |
From 1,260.00€
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Item number: ARG67069.100
Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine,...
Keywords: | Anti-MDR1, Anti-CD243, Anti-CD243, Anti-P-glycoprotein 1, Anti-P-glycoprotein 1, Anti-Multidrug resistance protein 1,... |
Application: | IHC (paraffin) |
Host: | Rabbit |
Species reactivity: | human |
624.00€
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Item number: Cay16672-5
Rhodamine 123 is a membrane-permeable cationic dye that is readily accumulated within living cells. It is a substrate for the efflux pump P-glycoprotein (P-gp, also known as multidrug resistance protein 1 and ABCB1) and is rapidly exported from cells with functional P-gp. As P-gp is expressed on a population of stem...
Keywords: | R-22420, R-302, RH123, 3,6-diamino-9-[2-(methoxycarbonyl)phenyl]-xanthylium, monochloride |
Application: | Membrane-permeable cationic dye, P-glycoprotein substrate, Mitochondrial stain |
CAS | 62669-70-9 |
MW: | 380.8 D |
From 43.00€
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-15 %
Discount Promotion
Item number: A303-625A
Protein function: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. [The UniProt Consortium]
Keywords: | Anti-MDR1, Anti-ABCB1, Anti-CD243, EC=3.6.3.44, Anti-P-glycoprotein 1, Anti-Multidrug resistance protein 1,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
164.00€
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From 139.40€
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Item number: Cay15421-5
Nobiletin is a polymethoxylated flavonoid that has been found in C. unshiu and has diverse biological activities. It reduces LPS- and IFN-gamma-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at concentrations of 25, 50, and 100 µM. Nobiletin...
Keywords: | NSC 618903, NSC 76751, 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one |
Application: | Natural polymethoxylated flavonoid |
CAS | 478-01-3 |
MW: | 402.4 D |
From 48.00€
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Item number: Cay24180-100
Tariquidar is an anthranilic acid derivative that binds to P-glycoprotein (Kd = 5.1 nM) and inhibits transport activity. It inhibits transport of vinblastine (Cay-11762) and paclitaxel (Cay-10461) in multidrug resistant CHrB30 cells, increasing the steady state accumulation to non-P-glycoprotein-expressing multidrug...
Keywords: | XR9576,... |
Application: | P-Glycoprotein inhibitor |
CAS | 206873-63-4 |
MW: | 646.7 D |
From 82.00€
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Item number: Cay21533-5
Zosuquidar is a modulator of P-glycoprotein (P-gp, Ki = 59 nM). It restores the sensitivity of P-gp-expressing cancer cells to vinblastine (Cay-11762), doxorubicin (Cay-15007), etoposide (Cay-12092), and paclitaxel (Cay-10461) when used at 0.1 µM. It less potently inhibits cytochrome P450 (CYP) isoforms CYP3A,...
Keywords: | LY335979, RS 33295-198,... |
Application: | P-glycoprotein modulator |
CAS | 167465-36-3 |
MW: | 637 D |
From 52.00€
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Item number: Cay18603-500
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a Kd value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma...
Keywords: | 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester... |
Application: | MDR1 modulator, Chemosensitizer |
CAS | 174630-04-7 |
MW: | 641.8 D |
From 46.00€
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