310 products were found matching "K05489"!
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NEW
Anti-IL-17A
Item number: E-AN005920L.100
Interleukin-17A (IL-17A), also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F)are encoded by separate genes but adopt a conserved cystine knot fold. Mature rat IL-17A shares 60% and 89% amino acid...
| Keywords: | Anti-Il17a, Anti-Ctla8, Anti-IL-17, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 109.00€
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NEW
Anti-IL-17A
Item number: E-D-AB-10452L.100
IL17A,also named as IL-17,is a proinflammatory cytokine. IL-17,synthesized only by memory T cells and natural killer cells,has pleiotropic effects,mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can...
| Keywords: | Anti-CTLA8, Anti-IL17A, Anti-IL-17, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 109.00€
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Interleukin-17A human Peptide Pool
Item number: PE-LB01966.1
Pool of 36 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Interleukin-17A human (UniProt ID: Q16552). One unit allows the stimulation of 2,5 x 10^8 cells. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and...
| Keywords: | CTLA8, IL17A, IL-17, CTLA-8, IL-17A, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8 |
| Origin: | human |
234.00€
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Y-320
Item number: TGM-T1846-100mg
Description: Y-320 is a new phenylpyrazoleanilide immunomodulator. Target: Interleukin, Lipase, IL Receptor. Smiles: Cc1c(cnn1-c1ccc(Cl)cc1)C(=O)Nc1ccc(N2CCC(CC2)N2CCOCC2)c(c1)C#N. References: Ushio H, et al. Pharmaceuticals (Basel). 2013, 7(1), 1-17.
| Keywords: | Y320 |
| Application: | Immunomodulatory agent |
| CAS | 288250-47-5 |
| MW: | 505.01 D |
From 41.00€
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Ixekizumab
Item number: TGM-T38105-10mg
Description: Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM. It blocks the binding of IL-17A to IL-17RA but not to other IL-17 family members. Ixekizumab is used for the treatment of moderate to severe plaque...
| Keywords: | LY2439821 |
| Application: | Targets interleukin 17A (IL17A, CTLA8) |
| CAS | 1143503-69-8 |
From 139.00€
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IL-17A inhibitor 2
Item number: TGM-T40116-5mg
Description: IL-17A inhibitor 2 is a compound used for treating psoriasis, rheumatoid arthritis, and multiple sclerosis by inhibiting IL-17A. Target: Others. Smiles: COC[C@@H](N1CC(NC1=O)C(F)(F)F)c1cnn2cc(nc2c1)[C@@H](NC(=O)c1nonc1C(F)F)C1CCC(F)(F)CC1 , @:10,35, . References: Sabnis RW. Imidazo[1,2-b]pyridazines as...
| Application: | IL-17A inhibitor |
| CAS | 2452464-77-4 |
| MW: | 622.505 D |
970.00€
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IL-17A inhibitor 1
Item number: TGM-T9448-1mg
Description: IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM. Target: IL Receptor. Smiles: COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)c1cnn2cc(nc2c1)[C@@H](NC(=O)c1nonc1C)C1CCC(F)(F)CC1. References: COATES DAVID ANDREW, et al....
| Keywords: | LY3509754 |
| Application: | IL-17A inhibitor |
| CAS | 2452464-73-0 |
| MW: | 586.51 D |
From 815.00€
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IL-17A Protein, Cynomolgus, Recombinant (His)
Item number: TGM-TMPJ-01444-10ug
Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is...
| Keywords: | IL-17A, IL-17, Cytotoxic T-Lymphocyte-Associated Antigen 8, Interleukin-17A, IL17, CTLA-8, CTLA8, IL17A |
| MW: | 25 kD |
From 124.00€
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IL-17 Protein, Mouse, Recombinant (His)
Item number: TGM-TMPJ-01172-10ug
Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties...
| Keywords: | IL17A, CTLA-8, Cytotoxic T-Lymphocyte-Associated Antigen 8, IL17, IL-17A, CTLA8, IL-17, Interleukin-17A |
| MW: | 26 kD |
From 83.00€
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IL-17A Protein, Cynomolgus, Recombinant (His & Avi)
Item number: TGM-TMPK-01266-100ug
Description: IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
| Keywords: | CTLA-8, IL-17CTLA-8, IL17A, IL17, interleukin 17A |
| MW: | 18.2 kD |
From 487.00€
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IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
Item number: TGM-TMPK-00975-100ug
Description: IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1.
| Keywords: | interleukin 17A, IL-17CTLA-8, CTLA-8, IL17A, IL17 |
| MW: | 18.2 kD |
From 814.00€
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IL-17A Protein, Mouse, Recombinant (His & Avi)
Item number: TGM-TMPK-01036-100ug
Description: IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
| Keywords: | interleukin 17A, IL-17CTLA-8, IL17, IL17A, CTLA-8 |
| MW: | 18 kD |
From 487.00€
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