385 products were found matching "K05489"!

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Elab Fluor(R)700 Anti-Human IL-17A Antibody[BL168]
Elab Fluor(R)700 Anti-Human IL-17A Antibody[BL168]

Item number: E-AB-F1173M1.100

IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial,...
Keywords: Anti-IL-17, Anti-IL17A, Anti-CTLA8, Anti-IL-17A, Anti-CTLA-8, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated...
Application: FC, FCM
Host: Mouse
Species reactivity: human
From 132.00€ *
Review
Elab Fluor(R)700 Anti-Mouse IL-17A Antibody[17F3]
Elab Fluor(R)700 Anti-Mouse IL-17A Antibody[17F3]

Item number: E-AB-F1272M1.100

The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, gammadelta T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and...
Keywords: Anti-IL-17, Anti-Il17a, Anti-Ctla8, Anti-IL-17A, Anti-CTLA-8, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated...
Application: FC, FCM
Host: Mouse
Species reactivity: mouse
From 66.00€ *
Review
Elab Fluor(R)700 Anti-Mouse IL-17A Antibody[17F3]
Elab Fluor(R)700 Anti-Mouse IL-17A Antibody[17F3]

Item number: E-AB-F1272UM1.100

The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, gammadelta T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and...
Keywords: Anti-IL-17, Anti-Il17a, Anti-Ctla8, Anti-IL-17A, Anti-CTLA-8, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated...
Application: FC, FCM
Host: Mouse
Species reactivity: mouse
From 97.00€ *
Review
Interleukin-17A human Peptide Pool
Interleukin-17A human Peptide Pool

Item number: PE-LB01966.1

Pool of 36 overlapping peptides derived from a peptide scan (15mers with 11 aa overlap) through Interleukin-17A human (UniProt ID: Q16552). One unit allows the stimulation of 2,5 x 10^8 cells. Protein function: Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and...
Keywords: CTLA8, IL17A, IL-17, CTLA-8, IL-17A, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8
Origin: human
234.00€ *
Review
Anti-IL-17A
Anti-IL-17A

Item number: E-AN005920L.100

Interleukin-17A (IL-17A), also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F)are encoded by separate genes but adopt a conserved cystine knot fold. Mature rat IL-17A shares 60% and 89% amino acid...
Keywords: Anti-Il17a, Anti-Ctla8, Anti-IL-17, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated...
Application: IHC
Host: Rabbit
Species reactivity: human
From 109.00€ *
Review
Anti-IL-17A
Anti-IL-17A

Item number: E-D-AB-10452L.100

IL17A,also named as IL-17,is a proinflammatory cytokine. IL-17,synthesized only by memory T cells and natural killer cells,has pleiotropic effects,mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can...
Keywords: Anti-CTLA8, Anti-IL17A, Anti-IL-17, Anti-CTLA-8, Anti-IL-17A, Anti-Interleukin-17A, Anti-Cytotoxic T-lymphocyte-associated...
Application: IHC
Host: Rabbit
Species reactivity: human
From 109.00€ *
Review
Ixekizumab
Ixekizumab

Item number: TGM-T38105-10mg

Description: Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM. It blocks the binding of IL-17A to IL-17RA but not to other IL-17 family members. Ixekizumab is used for the treatment of moderate to severe plaque...
Keywords: LY2439821
Application: Targets interleukin 17A (IL17A, CTLA8)
CAS 1143503-69-8
From 134.00€ *
Review
IL-17A inhibitor 2
IL-17A inhibitor 2

Item number: TGM-T40116-5mg

Description: IL-17A inhibitor 2 is a compound used for treating psoriasis, rheumatoid arthritis, and multiple sclerosis by inhibiting IL-17A. Target: Others. Smiles: COC[C@@H](N1CC(NC1=O)C(F)(F)F)c1cnn2cc(nc2c1)[C@@H](NC(=O)c1nonc1C(F)F)C1CCC(F)(F)CC1 , @:10,35, . References: Sabnis RW. Imidazo[1,2-b]pyridazines as...
Application: IL-17A inhibitor
CAS 2452464-77-4
MW: 622.505 D
970.00€ *
Review
IL-17A inhibitor 1
IL-17A inhibitor 1

Item number: TGM-T9448-1mg

Description: IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM. Target: IL Receptor. Smiles: COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)c1cnn2cc(nc2c1)[C@@H](NC(=O)c1nonc1C)C1CCC(F)(F)CC1. References: COATES DAVID ANDREW, et al....
Keywords: LY3509754
Application: IL-17A inhibitor
CAS 2452464-73-0
MW: 586.51 D
From 798.00€ *
Review
IL-17A Protein, Cynomolgus, Recombinant (His)
IL-17A Protein, Cynomolgus, Recombinant (His)

Item number: TGM-TMPJ-01444-10ug

Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is...
Keywords: IL-17A, IL-17, Cytotoxic T-Lymphocyte-Associated Antigen 8, Interleukin-17A, IL17, CTLA-8, CTLA8, IL17A
MW: 25 kD
From 122.00€ *
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IL-17 Protein, Mouse, Recombinant (His)
IL-17 Protein, Mouse, Recombinant (His)

Item number: TGM-TMPJ-01172-10ug

Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties...
Keywords: IL17A, CTLA-8, Cytotoxic T-Lymphocyte-Associated Antigen 8, IL17, IL-17A, CTLA8, IL-17, Interleukin-17A
MW: 26 kD
From 83.00€ *
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IL-17A Protein, Cynomolgus, Recombinant (His & Avi)
IL-17A Protein, Cynomolgus, Recombinant (His & Avi)

Item number: TGM-TMPK-01266-100ug

Description: IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
Keywords: CTLA-8, IL-17CTLA-8, IL17A, IL17, interleukin 17A
MW: 18.2 kD
From 485.00€ *
Review
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