101 products were found matching "K05426"!
No results were found for the filter!
Apilimod mesylate
Item number: TGM-T3533-100mg
Description: Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor. Target: Interleukin, PI3K, IL Receptor. Smiles: CS(O)(=O)=O.CS(O)(=O)=O.Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1. References: Wada Y, et al. Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23...
| Keywords: | STA 5326 mesylate |
| Application: | Targets interleukin 23 subunit alpha (IL23A) |
| CAS | 870087-36-8 |
| MW: | 610.7 D |
From 54.00€
*
Guselkumab
Item number: TGM-T38362-100mg
Description: Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab can inhibit the production of cytokines downstream of IL-23 signaling pathway, and can...
| Keywords: | CNTO 1959 |
From 649.00€
*
Risankizumab
Item number: TGM-T76778-10mg
Description: Risankizumab (BI 655066) is a humanized IgG monoclonal antibody (Kd <10 pM) targeting the IL-23 p19 subunit. It inhibits IL-17 production induced by human IL-23 in mouse splenocytes with an IC50 value of 2 pM. Risankizumab is used for the prevention and treatment of immune and inflammatory disorders...
| Keywords: | BI-655066, ABBV 066, Risankizumab rzaa, SKYRIZI |
| Application: | Targets interleukin 23 subunit alpha (IL23A) |
| CAS | 1612838-76-2 |
From 237.00€
*
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi),...
Item number: TGM-TMPK-01169-100ug
Description: The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and...
| Keywords: | IL-23 subunit alpha, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit alpha, Interleukin-23 subunit alpha, IL-23-A,... |
| MW: | 22.60 kD |
From 798.00€
*
IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)
Item number: TGM-TMPH-00779-100ug
Description: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates...
| Keywords: | Interleukin-23 subunit p19, IL23A, Interleukin-23 subunit alpha |
| MW: | 26.2 kD |
From 352.00€
*
IL-23 P19/IL23A Protein, Human, Recombinant (hFc)
Item number: TGM-TMPY-04874-100ug
Description: IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7.
| Keywords: | P19, IL23P19, SGRF, IL-23A, IL-23, interleukin 23, alpha subunit p19, interleukin 23, alpha subunit p19 |
| MW: | 45.4 kD |
From 239.00€
*
IL-23 P19/IL23A Protein, Human, Recombinant (mFc)
Item number: TGM-TMPY-04987-50ug
Description: IL-23 P19/IL23A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9NPF7.
| Keywords: | IL-23, SGRF, interleukin 23, alpha subunit p19, P19, IL-23A, IL23P19, interleukin 23, alpha subunit p19 |
| MW: | 45 kD |
375.00€
*
IL-23A Protein (Fc Tag) (recombinant mouse)
Item number: E-PDMM100097.100
Sequence: Val22-Ala196. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 40-50 kDa. Protein function: Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40...
| Keywords: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha, Recombinant Mouse... |
| Expressed in: | Mammalian |
| Origin: | mouse |
From 248.00€
*
IL23A & IL12B Heterodimer Protein (Active), human,...
Item number: CSB-AP004661HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 20-189aa & 23-328aa. Protein Length: Heterodimer. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG...
| Keywords: | SGRF, IL23A, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha, Recombinant... |
| Application: | Active protein |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 54.4 kD |
From 269.00€
*
Interleukin-23 subunit alpha (Il23a), mouse, recombinant
Item number: CSB-CF863641MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 22-196aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VPRSSSPDWA QCQQLSRNLC MLAWNAHAPA GHMNLLREEE DEETKNNVPR IQCEDGCDPQ GLKDNSQFCL QRIRQGLAFY KHLLDSDIFK...
| Keywords: | Il23a, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha, Recombinant Mouse... |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | mouse |
| MW: | 23.7 kD |
From 775.00€
*
Interleukin-23 subunit alpha (IL23A), swine, recombinant
Item number: CSB-CF873568PI.100
Organism: Sus scrofa (Pig). Source: in vitro E.coli expression system. Expression Region: 23-193aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RAVPEGSSPA WAQGQQLSQQ LCTLAWTAHL PMGHVDLPRE EGDDETTSEV PHIQCGDGCD PQGLRDNSQS...
| Keywords: | SGRF, IL23A, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha, Recombinant... |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | swine |
| MW: | 26.1 kD |
From 775.00€
*
Interleukin-23 subunit alpha (IL23A), guinea pig,...
Item number: CSB-EP757211GU.1
Organism: Cavia porcellus (Guinea pig). Source: E.coli. Expression Region: 20-189aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RAVSGSSNPS WTQCQQLSQK LCTLAWSAHP SVGHVEPPRE EADEETTDYV PHILCGDGCD PQGLKDNSQF CLQRIYQGLV FYQNLLGSDI...
| Keywords: | IL23A, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha, Recombinant... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | Cavia porcellus (Guinea pig) |
| MW: | 26.2 kD |
From 354.00€
*