60 products were found matching "K05361"!
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GPX4 Protein (Sumo Tag) (recombinant human)
Item number: E-PDEH100537.100
Sequence: Lys107-Phe197. Fusion tag: N-Sumo Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 20 kDa. Protein function: Protein function: Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and...
| Keywords: | PHGPx, GPx-4, GSHPx-4, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase GPX4, Recombinant Human... |
| Expressed in: | E.coli |
| Origin: | human |
From 248.00€
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(1S,3R)-RSL3
Item number: Cay19288-5
(1S,3R)-RSL3 is a ferroptosis inducer and is canonically known as an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits GPX4 in a context-dependent manner: (1S,3R)-RSL3 inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3epsilon, an adaptor protein, but does not inhibit recombinant human...
| Keywords: | (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid,... |
| Application: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.9 D |
From 43.00€
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GPX4 16
Item number: Cay40498-1
GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits the proliferation of Nthy-ori-3-1 transformed human thyroid follicular epithelial cells (IC50 = 8.39 µM), as well as MDA-T32 and MDA-T41 human thyroid cancer cells (IC50s = 10.29 and 8.18 µM, respectively). GPX4 16 (10 µM) induces ferroptosis in...
| Keywords: | Glutathione Peroxidase 4 16, 4-[(2E)-3-[2-(2-formylphenoxy)phenyl]-1-oxo-2-propen-1-yl]-benzonitrile |
| Application: | GPX4 inhibitor |
| CAS | 2644044-43-7 |
| MW: | 353.4 D |
From 90.00€
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Phospholipid hydroperoxide glutathione peroxidase (GPX4)...
Item number: CSB-EP009869HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-197aa(U73S). Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: CASRDDWRCA RSMHEFSAKD IDGHMVNLDK YRGFVCIVTN VASQSGKTEV NYTQLVDLHA RYAECGLRIL AFPCNQFGKQ EPGSNEEIKE FAAGYNVKFD MFSKICVNGD DAHPLWKWMK IQPKGKGILG...
| Keywords: | GPx-4, PHGPx, GSHPx-4, EC=1.11.1.12, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 23.4 kD |
From 283.00€
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Phospholipid hydroperoxide glutathione peroxidase (GPX4)...
Item number: CSB-YP009869HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 29-197aa(U73S). Protein Length: Partial. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: CASRDDWRCA RSMHEFSAKD IDGHMVNLDK YRGFVCIVTN VASQSGKTEV NYTQLVDLHA RYAECGLRIL AFPCNQFGKQ EPGSNEEIKE FAAGYNVKFD MFSKICVNGD DAHPLWKWMK IQPKGKGILG...
| Keywords: | GPx-4, PHGPx, GSHPx-4, EC=1.11.1.12, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase,... |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 21.4 kD |
From 395.00€
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Ferroptosis Inducer 24
Item number: Cay41201-1
Ferroptosis inducer 24 is an inducer of ferroptosis. It inhibits glutathione peroxidase 4 (GPX4) by 30-35% when used at a concentration of 50 µM. Ferroptosis inducer 24 (10 µM) increases the levels of heme oxygenase-1 (HO-1) in MDA-MB-231 triple-negative breast cancer cells, as well as increases the levels of...
| Keywords: | 3-phenyl-2-propenoic acid, 2-(1H-indol-3-yl)ethyl ester |
| Application: | Ferroptosis inducer |
| CAS | 28657-88-7 |
| MW: | 291.3 D |
From 47.00€
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Anti-GPX4
Item number: CSB-PA03049A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: GPX4. Antigen Species: Human
| Keywords: | Anti-GPx-4, Anti-PHGPx, Anti-GSHPx-4, EC=1.11.1.12, Anti-Glutathione peroxidase 4, Anti-Phospholipid hydroperoxide... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 163.00€
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NEW
Anti-GPX4 Recombinant Monoclonal, clone 9D4
Item number: CSB-RA188594A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: GPX4. Antigen Species: Human
| Keywords: | Anti-GPx-4, Anti-PHGPx, Anti-GSHPx-4, EC=1.11.1.12, Anti-Glutathione peroxidase 4, Anti-Phospholipid hydroperoxide... |
| Application: | ELISA, IHC, Recommended dilution: IHC:1:50-1:200 |
| Host: | Rabbit |
| Species reactivity: | human |
From 201.00€
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Liproxstatin-1
Item number: Cay17730-5
Liproxstatin-1 is a ferroptosis inhibitor. It inhibits ferroptotic cell death (IC50 = 22 nM) and lipid peroxidation in mouse embryonic fibroblasts (MEFs) with an inducible knockdown of glutathione peroxidase 4 (Gpx4-/- MEFs) when used at a concentration of 50 nM. Liproxstatin-1 also inhibits ferroptosis induced by...
| Keywords: | N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
| Application: | Ferroptosis inhibitor |
| CAS | 950455-15-9 |
| MW: | 340.9 D |
From 75.00€
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N6F11
Item number: Cay39919-25
N6F11 is an inducer of ferroptosis. It increases the thermal stability of the ubiquitin ligase TRIM25 in a cellular thermal shift assay (CETSA) using PANC-1 pancreatic cancer cells when used at a concentration of 10 µM and enhances TRIM25-dependent ubiquitination of glutathione peroxidase 4 (GPX4) in a cell-free...
| Keywords: | 2-(chloromethyl)-6-(4-chlorophenyl)-thieno[3,2-d]pyrimidin-4(3H)-one |
| Application: | Ferroptosis inducer, GPX4 degradation inducer |
| CAS | 851398-76-0 |
| MW: | 313.2 D |
From 47.00€
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Mouse GPX4 (Glutathione Peroxidase 4) ELISA Kit
Item number: ELK-ELK8786.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GPX4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GPX4. Next,...
| Keywords: | PHGPx, GPx-4, GSHPx-4, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase |
| Application: | ELISA |
| Species reactivity: | mouse |
From 365.00€
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Rat GPX4 (Glutathione Peroxidase 4) ELISA Kit
Item number: ELK-ELK0719.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GPX4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GPX4. Next,...
| Keywords: | PHGPx, GPx-4, GSHPx-4, Glutathione peroxidase 4, Phospholipid hydroperoxide glutathione peroxidase |
| Application: | ELISA |
| Species reactivity: | rat |
From 365.00€
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