48 products were found matching "K05357"!

Description: Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle. Target: Others. Smiles: O=C1C=2C=CC=CC2C(=O)C3(OC13C)CC=C(C)CCCC(C)CCCC(C)CCCC(C)C

Description: Tioclomarol is a coumarin anticoagulant and a vitamin K antagonist. Target: Others. Smiles: C(CC(O)C1=CC=C(Cl)C=C1)(C2=C(O)C=3C(OC2=O)=CC=CC3)C=4SC(Cl)=CC4

Description: Phenprocoumon is an antagonist of vitamin K(IC50:1 µM). Target: Others. Smiles: CCC(c1ccccc1)c1c(O)c2ccccc2oc1=O. References: Martin, Müller, Fabian, et al. Characteristics, treatment and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated...

Description: Warfarin-d5 is a deuterated compound of Warfarin. Smiles: C(CC(C)=O)(C1=C(O)C=2C(OC1=O)=CC=CC2)C3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H]

Description: (S)-Warfarin is a more effective enantiomer of Warfarin. It is used as a vitamin K antagonist, with anticoagulant. Target: Others. Smiles: [C@@H](CC(C)=O)(C1=C(O)C=2C(OC1=O)=CC=CC2)C3=CC=CC=C3. References: Seecheran R, Seecheran V, Persad S, Seecheran NA. Rivaroxaban as an Antithrombotic Agent in a...

Description: Tecarfarin (ATI-5923) is an orally active, potent vitamin K epoxide reductase (VKOR) antagonist and cannabinoid-1 receptor inverse agonist with antithrombotic activity, which attenuates abdominal pain and increases intestinal transit in mice. Target: Others. Smiles:...

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: VKORC1. Antigen Species: Human

(±)-Warfarin (Cay-13566) is a vitamin K antagonist, a coumarin derivative, and a racemic mixture of (+)-warfarin (Cay-13526) and (-)-warfarin (Cay-13531). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting...

Dicoumarol is a competitive inhibitor of NADH:quinone oxidoreductase (NQO1) with IC50 values of 2.6 and 404 nM in the absence and presence of 2 µM BSA, respectively. It has antiproliferative activity against MIA PaCa-2 pancreas and HCT116 colon carcinoma cells (IC50s = 52 and 19 µM, respectively, after a 96 hour...

(-)-Warfarin is a component of (±)-warfarin (Cay-13566). It is an anticoagulant that interferes with interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. In vivo, (-)-warfarin slows formation of the...

Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated in vitro. Acenocoumarol has a single chiral center that gives rise to two different enantiomeric...

Vitamin K is a dietary nutrient essential for the normal biosynthesis of factors that are required for blood clotting. It has also been shown to inhibit cell growth. Vitamin K1 2,3-epoxide is the inactive metabolite of vitamin K1. During clotting, vitamin K1 is converted to this epoxide form and then rapidly reduced...