45 products were found matching "K05220"!

Recombinant human P2RX7 protein with N-terminal human Fc tag. hFc(Glu99-Ala330) P2RX7(Ser47-Val334), Protein function: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in...

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The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse P2RX7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse P2RX7. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P2RX7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P2RX7. Next,...

The P2X purinergic receptors are ligand-gated ion channels that are activated by extracellular ATP. BzATP (ammonium salt) is an activator of the P2X receptors that exhibits 5-30-fold greater potency at the P2X7 receptor than ATP. It activates the human, rat, and mouse receptors with EC50 values of 0.7, 3.6, and 285...

A-438079 is a competitive antagonist of the nucleotide receptor P2X7 (pIC50 = 6.9). It inhibits both calcium flux and IL-1beta release mediated by P2X7 while not affecting the activity of other P2X receptors. A-438079 is effective in evaluating the role of P2X7 in nociception, oxidative stress, and apoptosis in...

Brilliant Blue G is a dye which is commonly used in laboratories to stain or quantify proteins. A variety of methods have been developed for using Brilliant Blue G to stain gels with ease and sensitivity. The Bradford assay is a standard, rapid dye-binding assay that uses Brilliant Blue G to quantify the amount of...

A-740003 is a competitive antagonist of the ATP-gated ionotropic P2X7 receptor (IC50s = 40 and 18 nM for human and rat receptors, respectively). It shows weak or no activity at other P2 receptors and other receptors and ion channels. A-740003 blocks agonist-induced IL-1beta release and pore formation in...

Protein function: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. [The UniProt...

Anti-P2RX7 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. P2RX7 antibody is human, mouse, and rat reactive. Multiple isoforms of P2RX7 are known to exist. Protein function: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene. The product of this gene belongs to the family of purnoceptors for ATP. P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization. It is a receptor...