82 products were found matching "K05209"!
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D-AP5
Item number: Cay14539-10
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (Kd = 1.4 µM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (-)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been...
| Keywords: | D-2-Amino-5-Phosphonovaleric Acid, D-APV, 5-phosphono-D-norvaline |
| Application: | NMDA receptor antagonist |
| CAS | 79055-68-8 |
| MW: | 197.1 D |
From 78.00€
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(RS)-(Tetrazol-5-yl)glycine
Item number: TGM-T16801-100mg
Description: (RS)-(Tetrazol-5-yl)glycine (LY 285265) [(D,L-(tetrazol-5-yl)glycine] is an effective and selective N-methyl-D-aspartate receptor agonist with EC50s of 99 nM for GluN1/GluN2D and 1.7 µM for GluN1/GluN2A. Target: NMDAR, iGluR. Smiles: NC(C(O)=O)c1nn[nH]n1. References: Schoepp DD, et al....
| Keywords: | D,L-(tetrazol-5-yl)glycine, LY 285265 |
| Application: | NMDA receptor agonist |
| CAS | 138199-51-6 |
| MW: | 143.1 D |
From 37.00€
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Rapastinel
Item number: TGM-T3407-10mg
Description: Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator. Target: NMDAR, iGluR. Smiles: C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(N)=O. References: Burgdorf J, et al. Neuroscience. 2015 Nov 12,308:202-11.
| Keywords: | GLYX-13, Thr-Pro-Pro-Thr-NH2, TPPT-amide |
| Application: | NMDAR modulator |
| CAS | 117928-94-6 |
| MW: | 413.47 D |
From 42.00€
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TCN 201
Item number: TGM-T7870-100mg
Description: TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit. Target: iGluR, NMDAR. Smiles: Fc1ccc(cc1Cl)S(=O)(=O)NCc1ccc(cc1)C(=O)NNC(=O)c1ccccc1. References: Hansen K B , Ogden K K , Traynelis S . Subunit-selective allosteric inhibition of glycine binding to NMDA receptors[J]....
| Keywords: | TCN-201 |
| Application: | NMDA receptor (NR2A) antagonist |
| CAS | 852918-02-6 |
| MW: | 461.89 D |
From 60.00€
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L-701324
Item number: TGM-T1909-100mg
Description: L-701324 is an NMDA receptor with high affinity and selectivity for the glycine site, used as an orally active and long-acting anticonvulsant. Target: NMDAR, iGluR. Smiles: Oc1c(-c2cccc(Oc3ccccc3)c2)c(=O)[nH]c2cc(Cl)ccc12. References: Wlaz P, Poleszak E. Pharmacol Rep. 2011,63(5):1231-4.
| Keywords: | L701324 |
| Application: | NMDA receptor antagonist |
| CAS | 142326-59-8 |
| MW: | 363.79 D |
From 34.00€
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Glutamate receptor ionotropic, NMDA 2A (GRIN2A),partial,...
Item number: CSB-EP618634HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 23-555aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VYQRAVMAVG SLTINEERSE VVDFSVPFVE TGISVMVSRS NGTVSPSAFL IGKAIWLLWG LVFNNSVPVQ NPKGTTSKIM MHQYMTKFNQ KGVEDALVSL KTGKLDAFIY DAAVLNYKAG RDEGCKLVTI. Purity:...
| Keywords: | NR2A, hNR2A, GRIN2A, GluN2A, NMDAR2A, Glutamate receptor ionotropic, NMDA 2A, N-methyl D-aspartate receptor subtype 2A,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 18.2 kD |
From 219.00€
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Anti-GRIN2A
Item number: CSB-PA14129A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: GRIN2A. Antigen Species: Human
| Keywords: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-GRIN2A
Item number: CSB-PA240091.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRIN2A. Antigen Species: Human
| Keywords: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-GRIN2A
Item number: CSB-PA545861.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRIN2A. Antigen Species: Human
| Keywords: | Anti-NR2A, Anti-hNR2A, Anti-GRIN2A, Anti-GluN2A, Anti-NMDAR2A, Anti-Glutamate receptor ionotropic, NMDA 2A, Anti-N-methyl... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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NMDA
Item number: Cay14581-50
NMDA is a synthetic amino acid derivative that acts as a specific agonist at the NMDA receptor, mimicking the excitatory action of the endogenous ligand glutamate. Signaling through the NMDA receptor influences both neuronal plasticity and neurotoxicity. Repetitive activation of NMDA synapses leads to long-term...
| Keywords: | N-Methyl-D-Aspartic Acid, N-methyl-D-aspartic acid |
| Application: | NMDA receptor agonist |
| CAS | 6384-92-5 |
| MW: | 147.1 D |
From 83.00€
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Memantine (hydrochloride)
Item number: Cay14184-100
Memantine is an NMDA receptor antagonist that blocks NMDA-induced currents in rat retinal ganglion cells by 90% when used at a concentration of 12 µM. It reverses inhibition of dephosphorylation of the synthetic tau phosphopeptide p17 (tau194-207) induced by the endogenous inhibitor of protein phosphatase 2A (PP2A)...
| Keywords: | Akatinol, Axura, Ebix, Namenda, NSC 102290, SUN Y7017, 3,5-dimethyl-tricyclo[3.3.1.13,7]decan-1-amine, monohydrochloride |
| Application: | NMDA open-channel blocker |
| CAS | 41100-52-1 |
| MW: | 215.8 D |
From 36.00€
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1-Aminocyclopropanecarboxylic Acid
Item number: Cay16132-100
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on...
| Keywords: | ACC, ACPC, NSC 98430, 1-amino-cyclopropanecarboxylic acid |
| Application: | Plant hormone precursor, NMDA receptor agonist |
| CAS | 22059-21-8 |
| MW: | 101.1 D |
From 44.00€
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