48 products were found matching "K05186"!

Description: GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude. Also inhibits 5-HT3A receptors via a similar mechanism. Target: GABA Receptor....

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GABRG2. Antigen Species: Human

Lorazepam-d4 (CRM) (Cay-18728) is intended for use as an internal standard for the quantification of lorazepam (Cay-ISO60202, Cay-15891) by GC- or LC-MS. Lorazepam is categorized as a benzodiazepine. It has anxiolytic properties and is a metabolite of diclazepam (Cay-28623, Cay-15554). Formulations containing...

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major...

Picrotoxin is a natural plant-derived poison that acts as a selective GABAA receptor antagonist. It is functional in vivo and is used to study the role of GABAA receptors in the central nervous system as well in the periphery. Picrotoxin induces seizures in adult and immature animals and is used to study...

Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected fromthe following species based on 100% sequence homology: bovine chicken, canine, human, mouse non-human...

Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric modulator of the GABAA receptor, potentiating GABA-activated chloride currents in a dose-dependent and reversible manner. Indiplon is selective for alpha1 subunits (EC50 = 2.6 nM) as compared with alpha2, alpha3, or alpha5 (EC50 = 24,...

4'-chloro Deschloroalprazolam (Cay-36057) is an analytical reference standard categorized as a benzodiazepine. This product is intended for research and forensic applications.Formal Name: 6-(4-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine. CAS Number: 92262-72-1. Molecular Formula: C17H13ClN4....

Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital, these are bound...

Protein function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital, these are bound...

Anti-GABA(A) Receptor gamma 2 Antibody is directed against rat GABA(A) Receptor gamma 2. The antibody was prepared from monospecific neat serum. Expect reactivity with the following species based on 100% sequence homology: bovine, chicken, human, mouse, non-human primates and zebra fish. Protein function: GABA, the...