112 products were found matching "K05121"!
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Razuprotafib
Item number: TGM-T16724-100mg
Description: Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor with an IC50 of 50 nM. It effectively activates Tie-2 and provides protection against acute kidney injury. Target: Phosphatase, Others. Smiles: COC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(NS(O)(=O)=O)cc1)c1csc(n1)-c1cccs1....
| Keywords: | AKB-9778 |
| Application: | Targets endothelial-specific receptor tyrosine kinase [EC:2.7.10.1] (TEK, TIE2, CD202) |
| CAS | 1008510-37-9 |
| MW: | 586.7 D |
From 251.00€
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Tie2 Inhibitor 7
Item number: TGM-T36718-1mg
Description: Tie2 Inhibitor 7 blocks Tie2 kinase activity with a Ki value of 1.3 µM. It has been shown to inhibit angiopoietin 1-induced Tie2 autophosphorylation and downstream signaling with an IC50 value of 0.3 µM. This compound can prevent endothelial cell tube formation and aberrant vessel growth in a rat model...
| Application: | Tie2 inhibitor |
| CAS | 1020412-97-8 |
| MW: | 529.63 D |
From 574.00€
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BAY-826
Item number: TGM-T38930-1mg
Description: BAY-826 is a novel, potent and selective TIE-2 inhibitor that inhibits TIE-2 phosphorylation and can be used to study tumors. Target: Tie-2. Smiles: Cc1cc(C)c(cc1NC(=O)c1cc(cc(c1)S(F)(F)(F)(F)F)C#N)-n1ccn2nc(cc12)-c1cccnc1. References: Schneider H,et al. Novel TIE-2 inhibitor BAY-826 displays in vivo...
| Application: | Tie2 inhibitor |
| CAS | 1448316-08-2 |
| MW: | 558.53 D |
69.00€
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EOC317
Item number: TGM-T4318-100mg
Description: EOC317 (ACTB-1003) is an oral kinase inhibitor with IC50 values of 6 nM, 2 nM, and 4 nM for FGFR1, VEGFR2, and Tie-2, respectively. Target: FGFR, VEGFR, Tie-2. Smiles: COCc1c(CN2CCOCC2)n2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)c(F)c1. References: Patel K, et al. ACTB-1003: An oral kinase...
| Keywords: | ACTB1003, ACTB 1003, ACTB-1003 |
| Application: | Multi-kinase inhibitor |
| CAS | 939805-30-8 |
| MW: | 591.53 D |
From 93.00€
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Pexmetinib
Item number: TGM-T6934-100mg
Description: Pexmetinib (ARRY-614) (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1. Target: Autophagy, p38 MAPK, Tie-2. Smiles: Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C. References: Koch K. 2013 AACR...
| Keywords: | ARRY-614 |
| Application: | Tie2 inhibitor, p38 MAPK inhibitor |
| CAS | 945614-12-0 |
| MW: | 556.63 D |
From 55.00€
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TIE2 Protein, Human, Recombinant (hFc)
Item number: TGM-TMPJ-00642-10ug
Description: TIE2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is Q02763-1.
| Keywords: | soluble TIE2 variant 2, CD202b, TEK tyrosine kinase, endothelial, EC 2.7.10, Tie2, hTIE2, VMCM, p140 TEK, angiopoietin-1... |
| MW: | 150 kD |
From 60.00€
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TIE2 Protein, Human, Recombinant (aa 23-745, His)
Item number: TGM-TMPJ-00643-10ug
Description: TIE2 Protein, Human, Recombinant (aa 23-745, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is Q02763-1.
| Keywords: | EC 2.7.10, EC 2.7.10.1, angiopoietin-1 receptor, Tie-2, soluble TIE2 variant 1, CD202b antigen, VMCM, CD202b, TEK tyrosine... |
| MW: | 120 kD |
From 52.00€
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TIE2 Protein, Rhesus, Recombinant (His)
Item number: TGM-TMPY-05049-100ug
Description: TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
| Keywords: | TEK tyrosine kinase, endothelial |
| MW: | 84.2 kD |
From 599.00€
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TIE2 Protein, Mouse, Recombinant (His), Biotinylated
Item number: TGM-TMPY-06974-100ug
Description: TIE2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.03 kDa and the accession number is Q02858.
| Keywords: | Hyk, Tie-2, Cd202b, TEK tyrosine kinase, endothelial, STK1, Tie2, AA517024 |
| MW: | 82.03 kD |
From 397.00€
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TIE2 Protein, Rat, Recombinant (hFc)
Item number: TGM-TMPY-02508-200ug
Description: TIE2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 108 kDa and the accession number is A6JRG8.
| Keywords: | TEK tyrosine kinase, endothelial |
| MW: | 108 kD |
599.00€
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TIE2 Protein, Human, Recombinant (His & GST)
Item number: TGM-TMPY-04545-50ug
Description: TIE2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is Q02763-1.
| Keywords: | TEK tyrosine kinase, endothelial, VMCM, CD202B, VMCM1, TIE-2, TIE2 |
| MW: | 68.3 kD |
397.00€
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TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
Item number: TGM-TMPY-04575-50ug
Description: TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.2kDa and the accession number is Q02858.
| Keywords: | AA517024, STK1, Cd202b, TEK tyrosine kinase, endothelial, Hyk, Tie2, Tie-2 |
| MW: | 68.2 kD |
397.00€
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