- Search results for K05101
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64 products were found matching "K05101"!
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Item number: ABS-PP-511.20
Keywords: | NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase,... |
Expressed in: | E.coli |
Origin: | human |
MW: | 55.5 kD |
From 90.00€
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Item number: TGM-T7435-100mg
Description: Selitrectinib (LOXO-195) is a potent and selective inhibitor of receptor tyrosine kinases TRK (TrkA and TrkC) with IC50 values of 0.6 nM and <2.5 nM, respectively. Target: Trk receptor. Smiles: [H][C@]12CCCN1c1ccn3ncc(C(=O)N[C@H](C)CCc4ncc(F)cc24)c3n1. References: Drilon A , Nagasubramanian R , Blake J...
Keywords: | LOXO-195 |
Application: | TrkA / TrkC inhibitor |
CAS | 2097002-61-2 |
MW: | 380.42 D |
From 34.00€
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Item number: TGM-TMPY-01223-100ug
Description: TrkC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q6VNS1-1.
Keywords: | Ntrk3_tv3, neurotrophic tyrosine kinase, receptor, type 3, AW125844, TrkC |
MW: | 46.1 kD |
599.00€
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Item number: TGM-TMPY-00944-100ug
Description: TrkC Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is Q16288-2.
Keywords: | neurotrophic tyrosine kinase, receptor, type 3, TRKC, gp145(trkC) |
MW: | 72.5 kD |
599.00€
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Item number: TGM-TMPY-00945-100ug
Description: TrkC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.1 kDa and the accession number is Q16288-2.
Keywords: | neurotrophic tyrosine kinase, receptor, type 3, gp145(trkC), TRKC |
MW: | 46.1 kD |
599.00€
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Item number: DIM-PME100566.10
Recombinant human NTRK3 protein with C-terminal human Fc tag. NTRK3(Cys32-Thr429) hFc(Glu99-Ala330), Protein function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling...
Keywords: | gp145(trkC), GP145-TrkC, TRKC |
Expressed in: | Human cells |
Origin: | human |
CAS | 12 |
MW: | 70.9 kD |
From 103.00€
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Item number: CSB-PA005017.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Keywords: | Anti-TRKC, Anti-Trk-C, Anti-NTRK3, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
From 126.00€
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Item number: CSB-PA020175.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Keywords: | Anti-phospho-TRKC, Anti-phospho-Trk-C, Anti-phospho-NTRK3, Anti-phospho-GP145-TrkC, EC=2.7.10.1, Anti-phospho-TrkC... |
Application: | ELISA, WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 126.00€
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Item number: 600-401-993
Protein function: Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. [The UniProt Consortium]
Keywords: | Anti-TrkC, Anti-Ntrk3, Anti-Trk-C, Anti-GP145-TrkC, EC=2.7.10.1, Anti-TrkC tyrosine kinase, Anti-NT-3 growth factor... |
Application: | ELISA, IP, WB |
Host: | Rabbit |
Species reactivity: | mouse |
719.00€
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Item number: Cay27062-1
LOXO-195 is an inhibitor of the receptor tyrosine kinases TrkA and TrkC (IC50s = 0.6 and G595R, TrkAG667C, TrkCG623R, and TrkCG696A (IC50s = 2, 9.8, 2.3, and 50 value of 1.9 nM. It selectively inhibits proliferation of Trk fusion-positive K12, CUTO-3, and MO-91 cell lines (IC50s = =5 nM) over Trk fusion-negative...
Keywords: | Selitrectinib,... |
Application: | TrkA / TrkC inhibitor |
CAS | 2097002-61-2 |
MW: | 380.4 D |
From 35.00€
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Item number: BPS-40282
Human TRKC, also known as NTKR3 (Neurotrophic Tyrosine Kinase Receptor, type 3) or NT-3 Receptor, GenBank Accession No. NM_002530, amino acids 456-825(end), with N-terminal GST-tag, MW=68kDa, expressed in Sf9 cells via a baculovirus expression system.
Keywords: | TRKC, Trk-C, NTRK3, GP145-TrkC, EC=2.7.10.1, TrkC tyrosine kinase, NT-3 growth factor receptor, Neurotrophic tyrosine... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Baculovirus |
Origin: | human |
MW: | 68 kD |
536.00€
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Item number: G-HUFI02675.96
ELISA Type: Sandwich. Detection Range: 0.156-10µg/mL. Sensitivity: 0.094µg/mL. Sample Types: Serum, Plasma. Protein function: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling...
Keywords: | TRKC, NTRK3, Trk-C, GP145-TrkC, EC=2.7.10.1, TrkC tyrosine kinase, NT-3 growth factor receptor, Neurotrophic tyrosine... |
Application: | Sandwich ELISA |
Species reactivity: | human |
641.00€
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