232 products were found matching "K05099"!
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Anti-MET (emibetuzumab biosimilar) mAb
Item number: DIM-BME100245.100
Research use only. ELISA 1:5000-10000, Flow Cyt 1:100. Protein function: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and...
| Keywords: | LA480, LY-2875358, LY2875358, Anti-MET, EC=2.7.10.1, Anti-SF receptor, Anti-HGF receptor, Anti-HGF/SF receptor,... |
| Application: | ELISA, FC |
| Host: | Human |
| Species reactivity: | human |
From 118.00€
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BAY-474
Item number: Cay41451-1
BAY-474 is an inhibitor of c-Met (IC50 = 98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Sparingly soluble: 1-10 mg/ml. SMILES: N#CC1=C(C)NC(C)=C(C1C2=CC3=C(NN=C3C)C=C2)C#N. InChi Code:...
| Keywords: | 1,4-dihydro-2,6-dimethyl-4-(3-methyl-1H-indazol-5-yl)-3,5-pyridinedicarbonitrile |
| Application: | c-Met inhibitor |
| CAS | 1033767-86-0 |
| MW: | 289.3 D |
From 59.00€
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AMG-458
Item number: TGM-T6378-5mg
Description: AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells. Target: c-Met/HGFR. Smiles: COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)nc3)ccnc2c1. References: Liu L, et al. J Med Chem, 2008, 51(13), 3688-3691.
| Keywords: | AMG 458 |
| Application: | c-Met inhibitor |
| CAS | 913376-83-7 |
| MW: | 539.58 D |
From 37.00€
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HGFR/c-Met Protein, Canine, Recombinant (His)
Item number: TGM-TMPY-02068-100ug
Description: HGFR/c-Met Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 103 kDa and the accession number is Q75ZY9.
| Keywords: | MET proto-oncogene, receptor tyrosine kinase |
| MW: | 103 kD |
599.00€
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HGFR/c-Met Protein, Mouse, Recombinant (hFc)
Item number: TGM-TMPY-01895-100ug
Description: HGFR/c-Met Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 128 kDa and the accession number is A4FUV6.
| Keywords: | Par4, HGFR, MET proto-oncogene, receptor tyrosine kinase, HGF, AI838057, c-Met |
| MW: | 128 kD |
From 497.00€
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HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His...
Item number: TGM-TMPY-04379-50ug
Description: HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P08581-1.
| Keywords: | RCCP2, HGFR, c-Met, DFNB97, MET proto-oncogene, receptor tyrosine kinase, AUTS9 |
| MW: | 76.8 kD |
497.00€
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Savolitinib
Item number: TGM-TQ0210-100mg
Description: Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met). Target: c-Met/HGFR. Smiles: C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1. References: Jia H, et al. Discovery of...
| Keywords: | Volitinib, AZD-6094, HMPL-504 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1313725-88-0 |
| MW: | 345.36 D |
From 42.00€
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Capmatinib
Item number: TGM-T1963-100mg
Description: Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. Target: Apoptosis, c-Met/HGFR. Smiles: CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1. References: Liu X, et al, Clin Cancer Res, 2011, 17(227). 7127-7138.
| Keywords: | NVP-INC280, INC-280, INCB28060 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1029712-80-8 |
| MW: | 412.42 D |
From 43.00€
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C-Met inhibitor D9
Item number: TGM-T67859-100mg
Description: C-Met inhibitor D9 is a c-Met kinase inhibitor. Target: c-Met/HGFR. Smiles: N(NC(CCC1=CC=CC=C1)=O)=C2C=3C(NC2=O)=CC=CC3. References: Liang Z, et al. Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase. Bioorg Med Chem Lett. 2011 Jun 15,21(12):3749-54.
| Application: | C-Met inhibitor |
| CAS | 299405-67-7 |
| MW: | 293.32 D |
From 194.00€
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PHA-665752
Item number: TGM-T6128-100mg
Description: PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs. Target: VEGFR, FGFR, Autophagy, Bcr-Abl, c-Met/HGFR, Apoptosis. Smiles:...
| Keywords: | PHA 665752, PHA665752 |
| Application: | ATP-competitive, active-site c-Met kinase inhibitor |
| CAS | 477575-56-7 |
| MW: | 641.61 D |
From 60.00€
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SU11274
Item number: TGM-T6154-100mg
Description: SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRbeta, EGFR or Tie2. Target: Apoptosis, c-Met/HGFR, CDK, Autophagy, VEGFR, FGFR. Smiles: C(=C\1/C=2C(NC1=O)=CC=C(S(N(C)C3=CC(Cl)=CC=C3)(=O)=O)C2)\C4=C(C)C(C(=O)N5CCN(C)CC5)=C(C)N4....
| Keywords: | PKI-SU11274, Met Kinase Inhibitor |
| Application: | c-Met inhibitor |
| CAS | 658084-23-2 |
| MW: | 568.09 D |
From 40.00€
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MK-2461
Item number: TGM-T6094-100mg
Description: MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with an average inhibitory concentration (IC50) of 2.5 nM. Target: c-Met/HGFR. Smiles: CN(C[C@@H]1COCCO1)S(=O)(=O)Nc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1....
| Keywords: | MK2461 |
| Application: | c-MET inhibitor |
| CAS | 917879-39-1 |
| MW: | 495.55 D |
From 48.00€
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