302 products were found matching "K05098"!
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Human VEGF R2/KDR Protein
Item number: KT-VGF-HM2R2-100UG
Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala20-Glu764. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell...
| Keywords: | KDR, FLK1, CD309, FLK-1, VEGFR-2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 109.21 kD |
From 245.00€
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Anti-VEGFR2 (human), Rabbit Monoclonal (RM515)
Item number: REV-31-1407-00-R100
Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vessel growth has not been previously...
| Keywords: | Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor,... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
542.00€
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Anti-KDR
Item number: ATA-HPA073577.100
Polyclonal Antibody against Human KDR, Gene description: kinase insert domain receptor, Alternative Gene Names: CD309, FLK1, VEGFR, VEGFR2, Validated applications: ICC, Uniprot ID: P35968, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Tyrosine-protein...
| Keywords: | Anti-KDR, Anti-FLK1, Anti-CD309, Anti-FLK-1, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
382.00€
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AG-13958
Item number: Cay41352-1
AG-13958 is an antagonist of VEGFR2 (Ki = 0.3 nM). It inhibits VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs, IC50 = 0.31 nM).Formal Name: N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide. CAS Number: 319460-94-1....
| Keywords: | N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide |
| Application: | VEGFR2 antagonist |
| CAS | 319460-94-1 |
| MW: | 467.5 D |
From 88.00€
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JNJ-38158471
Item number: Cay41361-10
JNJ-38158471 is an inhibitor of VEGFR2 (IC50 = 42 nM). It is selective for VEGFR2 over the PDGFR family kinases CSF-1 receptor tyrosine kinase (FMS), PDGFRalpha, FMS-related tyrosine kinase 3 (FLT3), and KIT (IC50s = 624, 1,109, 4,810, and 511 nM, respectively) and VEGFR family kinases VEGFR1 and VEGFR3 (IC50s =...
| Keywords: | N-[4-[[6-amino-5-[(methoxyimino)methyl]-4-pyrimidinyl]oxy]-2-chlorophenyl]-N'-ethyl-urea |
| Application: | VEGFR2 inhibitor |
| CAS | 951151-97-6 |
| MW: | 364.8 D |
From 272.00€
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Altiratinib
Item number: TGM-T2054-100mg
Description: Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor, effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro. Target: c-Met/HGFR, FLT, Tie-2, Trk receptor, VEGFR. Smiles:...
| Keywords: | DCC-2701 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
From 48.00€
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OSI-930
Item number: TGM-T2624-100mg
Description: OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors. Target: Apoptosis, FLT, Raf, c-Fms, Src, CSF-1R, c-Kit, VEGFR. Smiles:...
| Keywords: | OSI 930 |
| Application: | Kit / VEGFR2 dual inhibitor |
| CAS | 728033-96-3 |
| MW: | 443.44 D |
From 46.00€
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Chiauranib
Item number: TGM-T35570-100mg
Description: Chiauranib is a multi-target inhibitor against tumor angiogenesis and exhibits potent anticancer effects. Chiauranib potently inhibits the angiogenesis-related kinases (VEGFR1, VEGFR2, VEGFR3, PDGFRalpha and c-Kit), mitosis-related kinase Aurora B, and chronic inflammation-related kinase CSF1R, with...
| Keywords: | CS2164 |
| Application: | Multi-kinase inhibitor |
| CAS | 1256349-48-0 |
| MW: | 435.47 D |
From 83.00€
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SU5205
Item number: TGM-T3566-1mL
Description: SU5205 is a VEGFR2 inhibitor. Target: VEGFR. Smiles: Fc1ccc(C=C2C(=O)Nc3ccccc23)cc1. References: Tian XF, et al. PACE4 regulates apoptosis in human pancreatic cancer Panc 1 cells via the mitochondrial signaling pathway. Mol Med Rep. 2016 Dec,14(6):5205-5210.
| Keywords: | SU 5205 |
| Application: | VEGFR2 inhibitor |
| CAS | 3476-86-6 |
| MW: | 239.24 D |
30.00€
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4,4'-Bis(4-aminophenoxy)biphenyl
Item number: TGM-T35355-25mg
Description: 4,4'-Bis(4-aminophenoxy)biphenyl is a monomer for polyimide production. Target: Others. Smiles: O(C1=CC=C(C=C1)C2=CC=C(OC3=CC=C(N)C=C3)C=C2)C4=CC=C(N)C=C4
| Application: | VEGFR2 / Met / RET / Axl / Ron / PDGFR / FGFR1 / FLT1/3/4 inhibitor |
| CAS | 13080-85-8 |
| MW: | 368.43 D |
79.00€
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BFH772
Item number: TGM-T3599-100mg
Description: BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM....
| Keywords: | BFH-722 |
| Application: | VEGFR2 inhibitor |
| CAS | 890128-81-1 |
| MW: | 439.39 D |
From 40.00€
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Foretinib
Item number: TGM-T3113-100mg
Description: Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR. Target: Tie-2, c-Met/HGFR, VEGFR. Smiles: COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1. References: Qian F, et al. Inhibition of tumor cell growth,...
| Keywords: | EXEL-2880, GSK1363089, XL880, GSK089 |
| Application: | Targets kinase insert domain protein receptor [EC:2.7.10.1] (KDR, VEGFR2, CD309) |
| CAS | 849217-64-7 |
| MW: | 632.65 D |
From 34.00€
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