301 products were found matching "K05098"!
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Vascular endothelial growth factor receptor 2 (KDR),...
Item number: CSB-MP012145HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 20-764aa. Protein Length: Partial. Tag Info: C-terminal hFc-tagged. Target Protein Sequence: ASVGLPSVSL DLPRLSIQKD ILTIKANTTL QITCRGQRDL DWLWPNNQSG SEQRVEVTEC SDGLFCKTLT IPKVIGNDTG AYKCFYRETD LASVIYVYVQ DYRSPFIASV SDQHGVVYIT ENKNKTVVIP...
| Keywords: | KDR, FLK1, CD309, FLK-1, VEGFR-2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor... |
| Application: | Activity not tested |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 112.1 kD |
From 101.00€
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Anti-VEGFR2 (human), Rabbit Monoclonal (RM515)
Item number: REV-31-1407-00-R100
Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vessel growth has not been previously...
| Keywords: | Anti-KDR, Anti-FLK1, Anti-FLK-1, Anti-CD309, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor,... |
| Application: | IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
542.00€
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Anti-KDR
Item number: ATA-HPA073577.100
Polyclonal Antibody against Human KDR, Gene description: kinase insert domain receptor, Alternative Gene Names: CD309, FLK1, VEGFR, VEGFR2, Validated applications: ICC, Uniprot ID: P35968, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Tyrosine-protein...
| Keywords: | Anti-KDR, Anti-FLK1, Anti-CD309, Anti-FLK-1, Anti-VEGFR-2, Anti-Fetal liver kinase 1, Anti-Kinase insert domain receptor,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
382.00€
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Human VEGF R2/KDR Protein
Item number: KT-VGF-HM2R2-100UG
Recombinant Human VEGF R2/KDR Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala20-Glu764. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell...
| Keywords: | KDR, FLK1, CD309, FLK-1, VEGFR-2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 109.21 kD |
From 245.00€
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AG-13958
Item number: Cay41352-1
AG-13958 is an antagonist of VEGFR2 (Ki = 0.3 nM). It inhibits VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs, IC50 = 0.31 nM).Formal Name: N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide. CAS Number: 319460-94-1....
| Keywords: | N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide |
| Application: | VEGFR2 antagonist |
| CAS | 319460-94-1 |
| MW: | 467.5 D |
From 88.00€
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JNJ-38158471
Item number: Cay41361-10
JNJ-38158471 is an inhibitor of VEGFR2 (IC50 = 42 nM). It is selective for VEGFR2 over the PDGFR family kinases CSF-1 receptor tyrosine kinase (FMS), PDGFRalpha, FMS-related tyrosine kinase 3 (FLT3), and KIT (IC50s = 624, 1,109, 4,810, and 511 nM, respectively) and VEGFR family kinases VEGFR1 and VEGFR3 (IC50s =...
| Keywords: | N-[4-[[6-amino-5-[(methoxyimino)methyl]-4-pyrimidinyl]oxy]-2-chlorophenyl]-N'-ethyl-urea |
| Application: | VEGFR2 inhibitor |
| CAS | 951151-97-6 |
| MW: | 364.8 D |
From 272.00€
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Cabozantinib S-malate
Item number: TGM-T1797-100mg
Description: Cabozantinib S-malate (XL184) is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Target: Apoptosis, c-Met/HGFR, VEGFR, TAM Receptor, c-Kit. Smiles:...
| Keywords: | XL184, Cabozantinib Malate, Cabozantinib |
| Application: | Targets kinase insert domain protein receptor [EC:2.7.10.1] (KDR, VEGFR2, CD309) |
| CAS | 1140909-48-3 |
| MW: | 635.59 D |
From 42.00€
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Golvatinib
Item number: TGM-T6517-100mg
Description: Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of...
| Keywords: | E-7050 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 928037-13-2 |
| MW: | 633.69 D |
From 40.00€
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RAF265
Item number: TGM-T6296-100mg
Description: RAF265 (CHIR-265) (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2. Target: VEGFR, Raf, Autophagy, Apoptosis. Smiles:...
| Keywords: | CHIR-265 |
| Application: | B-Raf V600E / VEGFR2 inhibitor |
| CAS | 927880-90-8 |
| MW: | 518.41 D |
From 40.00€
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Dovitinib
Item number: TGM-T6289-100mg
Description: Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to EGFR, InsR, EphA2, c-Met, IGF-1R, Tie2, and HER2. Target: VEGFR, FGFR, c-Kit,...
| Keywords: | CHIR-258, TKI258 |
| Application: | PDGFRB / VEGFR2 / FGFR1 inhibitor |
| CAS | 405169-16-6 |
| MW: | 392.43 D |
From 40.00€
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Altiratinib
Item number: TGM-T2054-100mg
Description: Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor, effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro. Target: c-Met/HGFR, FLT, Tie-2, Trk receptor, VEGFR. Smiles:...
| Keywords: | DCC-2701 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
From 48.00€
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OSI-930
Item number: TGM-T2624-100mg
Description: OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors. Target: Apoptosis, FLT, Raf, c-Fms, Src, CSF-1R, c-Kit, VEGFR. Smiles:...
| Keywords: | OSI 930 |
| Application: | Kit / VEGFR2 dual inhibitor |
| CAS | 728033-96-3 |
| MW: | 443.44 D |
From 46.00€
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