- Search results for K05096
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169 products were found matching "K05096"!
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Item number: CSB-RA008732MA1HU.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
Keywords: | Anti-FLT, Anti-FLT1, Anti-FLT-1, Anti-VEGFR-1, EC=2.7.10.1, Anti-Fms-like tyrosine kinase 1, Anti-Tyrosine-protein kinase... |
Application: | ELISA, IHC |
Host: | Human |
Species reactivity: | human |
From 186.00€
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Item number: ABS-KC-756.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
Keywords: | Anti-Vascular endothelial growth factor receptor 1, Anti-VEGFR-1, Anti-Fms-like tyrosine kinase 1, Anti-FLT-1,... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
From 206.00€
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Item number: ABS-KC-757.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
Keywords: | Anti-Vascular endothelial growth factor receptor 1, Anti-VEGFR-1, Anti-Fms-like tyrosine kinase 1, Anti-FLT-1,... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
From 206.00€
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Item number: ABS-KC-758.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a...
Keywords: | Anti-Vascular endothelial growth factor receptor 1, Anti-VEGFR-1, Anti-Fms-like tyrosine kinase 1, Anti-FLT-1,... |
Application: | IHC |
Host: | Mouse |
Species reactivity: | human |
From 206.00€
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Item number: TGM-T6720-100mg
Description: Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4. Target: VEGFR, Apoptosis, PDGFR. Smiles: Cl.Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1. References: Wood JM, et al. Cancer Res....
Keywords: | ZK-222584 dihydrochloride, CGP-797870 dihydrochloride, CGP-79787 dihydrochloride, Vatalanib 2HCl, PTK787 dihydrochloride,... |
Application: | VEGFR inhibitor |
CAS | 212141-51-0 |
MW: | 419.73 D |
From 42.00€
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Item number: TGM-T1452-1g
Description: Axitinib (AG-013736) is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.7, 1.6 nM for VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRbeta, respectively. Target: PDGFR, VEGFR, c-Kit. Smiles: C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2. References: Hu-Lowe...
Keywords: | AG-013736 |
Application: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
CAS | 319460-85-0 |
MW: | 386.47 D |
From 34.00€
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Item number: E-AN000160P.1
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA,VEGFB and PGF,and plays an essential role in the development of embryonic vasculature,the regulation of angiogenesis,cell survival,cell migration,macrophage function,chemotaxis,and cancer cell invasion. Acts as a positive regulator of postnatal...
Keywords: | Anti-FLT, Anti-FLT1, Anti-FLT-1, Anti-VEGFR-1, EC=2.7.10.1, Anti-Fms-like tyrosine kinase 1, Anti-Tyrosine-protein kinase... |
Application: | ELISA Capture/Detector |
Host: | Rabbit |
Species reactivity: | human |
From 158.00€
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Item number: TGM-T12925-100mg
Description: Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively.) , shows potent single-agent antitumor...
Keywords: | MG-516 malate, MGCD516 malate |
Application: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
CAS | 2244864-88-6 |
MW: | 763.76 D |
From 1,520.00€
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Item number: TGM-T21593-100mg
Description: AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities. Target: VEGFR. Smiles:...
Application: | VEGF receptor inhibitor |
CAS | 269390-77-4 |
MW: | 371.36 D |
From 40.00€
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Item number: TGM-T4349-100mg
Description: Sitravatinib (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRalpha/beta, PDGFR, and Axl. Target: VEGFR, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor, FLT, Discoidin Domain Receptor (DDR). Smiles:...
Keywords: | MG516, MGCD516 |
Application: | Targets AXL receptor tyrosine kinase [EC:2.7.10.1] (AXL, UFO) |
CAS | 1123837-84-2 |
MW: | 629.68 D |
From 46.00€
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Item number: TGM-T7493-100mg
Description: AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration. Target: VEGFR. Smiles: Cc1cnn(C)c1C(=O)Nc1cc(Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)ccc1F. References: Barakat M R , Kaiser P . VEGF inhibitors for the treatment of neovascular...
Keywords: | AG-013958 |
Application: | FLT/TYK receptor inhibitor |
CAS | 319460-94-1 |
MW: | 467.5 D |
From 98.00€
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Item number: TGM-T7611-100mg
Description: ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Target: VEGFR, FGFR. Smiles: Cn1cc(cn1)-c1ccc2n(cnc2c1)-c1cc(NS(=O)(=O)C2CC2)cc(c1)-c1ccc(F)cc1F. References: Tim H Holmström , Anu-Maarit Moilanen , Tarja Ikonen,et al.ODM-203, a...
Application: | VEGFR / FGFR dual inhibitor |
CAS | 1430723-35-5 |
MW: | 505.54 D |
From 37.00€
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