44 products were found matching "K05051"!

Description: Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and MONOAMINE OXIDASE to prolong the actions of adrenergic transmitters. It also...

Description: 3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart...

Description: RO5166017 is an orally active, potent and selective trace amine-associated receptor 1 (TAAR1) agonist for the study of conditioned taste aversion frontal nerve disorders. Target: Others. Smiles: CCN(C[C@H]1COC(N)=N1)c1ccccc1. References: Justin N Siemian, et al. Trace amine-associated receptor 1...

Description: Ralmitaront (RO6889450) is a potent, orally active partial agonist of the trace amine-associated receptor 1 (TAAR1). Target: Others. Smiles: CCc1[nH]nc(C(=O)Nc2ccc(cc2)[C@H]2CNCCO2)c1C. References: Brady LS, Potter WZ, Gordon JA. Redirecting the revolution: new developments in drug development for...

Description: Ro 5212773 (Epptb) is a selective TAAR1 antagonist. Target: Others. Smiles: CCOc1cccc(NC(=O)c2ccc(N3CCCC3)c(c2)C(F)(F)F)c1. References: Bradaia A , Trube G , Stalder H , et al. The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic...

Description: Ractopamine-d3 hydrochloride is a deuterated compound of Ractopamine hydrochloride. Ractopamine hydrochloride has a CAS number of 90274-24-1. Smiles: C(C(NC(CCC1=CC=C(O)C=C1)C)([2H])[2H])(O)(C2=CC=C(O)C=C2)[2H].Cl

Ralmitaront is an agonist of trace amine-associated receptor 1 (TAAR1). It induces cAMP accumulation in HEK293T cells expressing human TAAR1 (EC50 = 17.78 nM).Formal Name: 5-ethyl-4-methyl-N-[4-(2S)-2-morpholinylphenyl]-1H-pyrazole-3-carboxamide. CAS Number: 2133417-13-5. Synonyms: RG-7906, RO6889450. Molecular...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TAAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TAAR2. Next,...

3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and...

Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist. It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively). Tyramine also inhibits the release of norepinephrine and dopamine in isolated rat...

Tyramine-d4 is intended for use as an internal standard for the quantification of tyramine (Cay-18601) by GC- or LC-MS. Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist. It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and...

Not expressed in the pons, thalamus, hypothalamus, hippocampus, caudate, putamen, frontal cortex, basal forebrain, midbrain or liver. Protein function: Orphan receptor. [The UniProt Consortium]