41 products were found matching "K05051"!

Ralmitaront is an agonist of trace amine-associated receptor 1 (TAAR1). It induces cAMP accumulation in HEK293T cells expressing human TAAR1 (EC50 = 17.78 nM).Formal Name: 5-ethyl-4-methyl-N-[4-(2S)-2-morpholinylphenyl]-1H-pyrazole-3-carboxamide. CAS Number: 2133417-13-5. Synonyms: RG-7906, RO6889450. Molecular...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TAAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TAAR2. Next,...

3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G protein-coupled receptor known as trace amine-associated receptor 1 at nanomolar concentrations whereupon it rapidly influences thyroid hormone actions including body temperature, heart rate, and...

Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist. It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively). Tyramine also inhibits the release of norepinephrine and dopamine in isolated rat...

Tyramine-d4 is intended for use as an internal standard for the quantification of tyramine (Cay-18601) by GC- or LC-MS. Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist. It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and...

Not expressed in the pons, thalamus, hypothalamus, hippocampus, caudate, putamen, frontal cortex, basal forebrain, midbrain or liver. Protein function: Orphan receptor. [The UniProt Consortium]

RO5166017 is an agonist of trace amine-associated receptor 1 (TAAR1). It binds to TAAR1 (Kis = 31, 24, 1.9, and 2.7 nM in HEK293 cells expressing the recombinant human, cynomolgus monkey, mouse, or rat receptor, respectively) and is greater than 15-fold selective for TAAR1 over a panel of 123 receptors, ion...

EPPTB is an antagonist of trace amine-associated receptor 1 (TAAR1, Ki = 0.9 nM for the mouse receptor). It selectively inhibits beta-phenylethylamine-induced cAMP production in HEK293 cells expressing mouse TAAR1 over human or rat TAAR1 (IC50s = 27.5, 7,487, and 4,539 nM, respectively). EPPTB (10 nM) reduces...

TAAR5 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human, Rat, Mouse and for use in ELISA, WB, IHC, IF applications. TAAR5 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Olfactory receptor specific for trimethylamine, a trace amine. Also...

Protein function: Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably...

Protein function: Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace...

Ractopamine is a trace amine-associated receptor 1 (TAAR1) agonist. It increases chloride conductance in X. laevis oocytes expressing the human cystic fibrosis transmembrane conductance regulator (CFTR) and mouse TAAR1 (EC50 = 16 µM), an effect that can be blocked by the TAAR1 antagonist EPPTB (Cay-34330). It...